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FERM, ARHGEF and pleckstrin domain-containing protein 1

Summary

UniProt ID

Q9Y4F1

Gene Symbol

CDEP
FARP1
PLEKHC2

Gene ID

10160

Organism

Homo sapiens (human)

External Links

PubChem: Q9Y4F1
The Human Metabolome Database: HMDBP08127
The O-GlcNAc Database: Q9Y4F1
RaftProt: Q9Y4F1
Re-Glyco: Q9Y4F1

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Cell projection
Cytoplasm
Developmental protein
Guanine-nucleotide releasing factor
Phosphoprotein
Reference proteome
Repeat
Synaptosome

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
cytoskeleton
dendrite
cytosol
cytoplasmic side of plasma membrane
filopodium
dendritic spine
glutamatergic synapse
extrinsic component of postsynaptic membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying **all 8** entries
GO Term
dendrite morphogenesis
enzyme-linked receptor protein signaling pathway
synapse assembly
Rac protein signal transduction
retrograde trans-synaptic signaling by trans-synaptic protein complex
postsynaptic actin cytoskeleton organization
positive regulation of skeletal muscle acetylcholine-gated channel clustering
regulation of presynapse assembly

Displaying **all 3** entries
GO Term
guanyl-nucleotide exchange factor activity
cytoskeletal protein binding
small GTPase binding

Annotation information from UniProt.

Sequence

MGEIEQRPTPGSRLGAPENSGISTLERGQKPPPTPSGKLVSIKIQMLDDTQEAFEVPQRAPGKVLLDAVCNHLNLVEGDYFGLEFPDHKKITVWLDLLKPIVKQIRRPKHVVVKFVVKFFPPDHTQLQEELTRYLFALQVKQDLAQGRLTCNDTSAALLISHIVQSEIGDFDEALDREHLAKNKYIPQQDALEDKIVEFHHNHIGQTPAESDFQLLEIARRLEMYGIRLHPAKDREGTKINLAVANTGILVFQGFTKINAFNWAKVRKLSFKRKRFLIKLRPDANSAYQDTLEFLMASRDFCKSFWKICVEHHAFFRLFEEPKPKPKPVLFSRGSSFRFSGRTQKQVLDYVKEGGHKKVQFERKHSKIHSIRSLASQPTELNSEVLEQSQQSTSLTFGEGAESPGGQSCRRGKEPKVSAGEPGSHPSPAPRRSPAGNKQADGAASAPTEEEEEVVKDRTQQSKPQPPQPSTGSLTGSPHLSELSVNSQGGVAPANVTLSPNLSPDTKQASPLISPLLNDQACPRTDDEDEGRRKRFPTDKAYFIAKEVSTTERTYLKDLEVITSWFQSTVSKEDAMPEALKSLIFPNFEPLHKFHTNFLKEIEQRLALWEGRSNAQIRDYQRIGDVMLKNIQGMKHLAAHLWKHSEALEALENGIKSSRRLENFCRDFELQKVCYLPLNTFLLRPLHRLMHYKQVLERLCKHHPPSHADFRDCRAALAEITEMVAQLHGTMIKMENFQKLHELKKDLIGIDNLVVPGREFIRLGSLSKLSGKGLQQRMFFLFNDVLLYTSRGLTASNQFKVHGQLPLYGMTIEESEDEWGVPHCLTLRGQRQSIIVAASSRSEMEKWVEDIQMAIDLAEKSSSPAPEFLASSPPDNKSPDEATAADQESEDDLSASRTSLERQAPHRGNTMVHVCWHRNTSVSMVDFSIAVENQLSGNLLRKFKNSNGWQKLWVVFTNFCLFFYKSHQDNHPLASLPLLGYSLTIPSESENIQKDYVFKLHFKSHVYYFRAESEYTFERWMEVIRSATSSASRPHVLSHKESLVY

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites