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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Heparan sulfate glucosamine 3-O-sulfotransferase 4
Summary
- UniProt ID
- Q9Y661
- Gene Symbol
-
- HS3ST4
- 3OST4
- Organism
- Homo sapiens (human)
External Links
- The Human Metabolome Database
- HMDBP00349
Annotation
- Keyword
-
- Disulfide bond
- Glycoprotein
- Golgi apparatus
- Proteomics identification
- Reference proteome
- Signal-anchor
- Transferase
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| heparan sulfate proteoglycan biosynthetic process |
| heparan sulfate proteoglycan metabolic process |
| GO Term |
|---|
| Golgi membrane |
| GO Term |
|---|
| [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity |
Sequence
MARWPAPPPPPPPPPPLAAPPPPGASAKGPPARKLLFMCTLSLSVTYLCYSLLGGSGSLQFPLALQESPGAAAEPPPSPPPPSLLPTPVRLGAPSQPPAPPPLDNASHGEPPEPPEQPAAPGTDGWGLPSGGGGAQDAWLRTPLAPSEMITAQSALPEREAQESSTTDEDLAGRRAANGSSERGGAVSTPDYGEKKLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDRNYEKGLEWYRNVMPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKPEIPTFEVLAFKNRTLGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLIVDPAGEMAKVQDFLGLKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRIDPDVIHRLRKFYKPFNLMFYQMTGQDFQWEQEEGDK
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| HS-GAG biosynthesis | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080147 | lymphoblastic lymphoma | |
| DOID:10871 | age related macular degeneration | |
| DOID:2007 | degeneration of macula and posterior pole | |
| DOID:4448 | macular degeneration | |
| DOID:670 | amphetamine abuse | |
| DOID:9952 | acute lymphoblastic leukemia |
