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Sodium bicarbonate cotransporter 3

Summary

UniProt ID

Q9Y6M7

Gene Symbol

SLC4A7
BT
NBC2
NBC2B
NBC3
NBCn1
SBC2
SLC4A6

Organism

Homo sapiens (human)

External Links

GlyGen: Q9Y6M7
PubChem: Q9Y6M7
The Human Metabolome Database: HMDBP03231
The O-GlcNAc Database: Q9Y6M7
RaftProt: Q9Y6M7
O-GlcNAcAtlas: Q9Y6M7

Annotation

Keyword

Alternative splicing
Cell membrane
Cell projection
Disulfide bond
Glycoprotein
Phosphoprotein
Reference proteome
Sodium transport
Symport
Transmembrane helix

Gene Ontology (GO)

Displaying **all 8** entries
GO Term
transmembrane transport
auditory receptor cell development
bicarbonate transport
purine nucleotide biosynthetic process
regulation of intracellular pH
cellular response to growth factor stimulus
phagosome acidification
pyrimidine nucleotide biosynthetic process

Displaying **all 5** entries
GO Term
plasma membrane
membrane
basolateral plasma membrane
apical plasma membrane
stereocilium

Displaying **all 3** entries
GO Term
monoatomic anion transmembrane transporter activity
sodium:bicarbonate symporter activity
solute:inorganic anion antiporter activity

Annotation information from UniProt.

Sequence

MERFRLEKKLPGPDEEAVVDLGKTSSTVNTKFEKEELESHRAVYIGVHVPFSKESRRRHRHRGHKHHHRRRKDKESDKEDGRESPSYDTPSQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWSKPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVREALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGEGLSASRHSLRTGLSASNLSLRGESPLSLLLGHLLPSSRAGTPAGSRCTTPVPTPQNSPPSSPSISRLTSRSSQESQRQAPELLVSPASDDIPTVVIHPPEEDLEAALKGEEQKNEENVDLTPGILASPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDFLERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFHDVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTPTLGETPKEAAHHAGPELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASILFLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLVFEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICIIFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSNETLAQWKKDNITAHNISWRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSFLKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWIISPLGDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVMLGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGLSVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWKVHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPESKKKKEDDKKKKEKEEAERMLQDDDDTVHLPFEGGSLLQIPVKALKYSPDKPVSVKISFEDEPRKKYVDAETSL

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 10** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
171	N-linked (GlcNAc...) asparagine			UniProt GlyGen
269	N-linked (GlcNAc...) asparagine		G80920RR	UniProt GlyGen
398	N-linked (GlcNAc...) asparagine			UniProt GlyGen
406	N-linked (GlcNAc...) asparagine			UniProt GlyGen
554			G41840AI	GlyGen
776	N-linked (GlcNAc...) asparagine	19349973		UniProt GlyGen
786	N-linked (GlcNAc...) asparagine	19349973	G80920RR	UniProt GlyGen
791	N-linked (GlcNAc...) asparagine	19349973	G41429FA	UniProt GlyGen
796			G03644CB G40574BA G63041LO G62765YT G28541PG G31852PQ G41247ZX	GlyGen
800			G49108TO	GlyGen The O-GlcNAc Database

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
Bicarbonate transporters	Homo sapiens
RHOD GTPase cycle	Homo sapiens
RHOF GTPase cycle	Homo sapiens
RHOH GTPase cycle	Homo sapiens
RHOJ GTPase cycle	Homo sapiens
RHOQ GTPase cycle	Homo sapiens

Human Protein Atlas

ENSG00000033867

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

Search Tools

Summary

External Links

Annotation

International Collaboration

Acknowledgements