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Lymphocyte antigen 96

Summary

UniProt ID

Q9Y6Y9

Gene Symbol

ESOP1
LY96
MD2

Gene ID

23643

Organism

Homo sapiens (human)

External Links

GlyGen: Q9Y6Y9
PubChem: Q9Y6Y9
The Human Metabolome Database: HMDBP13763
Re-Glyco: Q9Y6Y9

Annotation

Keyword

3D-structure
Alternative splicing
Disulfide bond
Glycoprotein
Inflammatory response
Innate immunity
Reference proteome
Secreted
Signal

Gene Ontology (GO)

Displaying **all 5** entries
GO Term
extracellular region
plasma membrane
lipopolysaccharide receptor complex
receptor complex
endosome membrane

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 11 in total

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GO Term
inflammatory response
cell surface receptor signaling pathway
innate immune response
cellular response to lipopolysaccharide
toll-like receptor 4 signaling pathway
cellular defense response
positive regulation of lipopolysaccharide-mediated signaling pathway
detection of lipopolysaccharide
toll-like receptor signaling pathway
response to lipopolysaccharide

Displaying **all 4** entries
GO Term
coreceptor activity
lipopolysaccharide binding
lipopolysaccharide immune receptor activity
Toll-like receptor 4 binding

Annotation information from UniProt.

Sequence

MLPFLFFSTLFSSIFTEAQKQYWVCNSSDASISYTYCDKMQYPISINVNPCIELKRSKGLLHIFYIPRRDLKQLYFNLYITVNTMNLPKRKEVICRGSDDDYSFCRALKGETVNTTISFSFKGIKFSKGKYKCVVEAISGSPEEMLFCLEFVILHQPNSN

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
26	N-linked (GlcNAc...) asparagine	17569869		UniProt GlyGen
114	N-linked (GlcNAc...) asparagine	17569869		UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying entries **1 - 10** of 17 in total

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Pathway Name	Organism
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE)	Homo sapiens
ER-Phagosome pathway	Homo sapiens
Heme signaling	Homo sapiens
IKK complex recruitment mediated by RIP1	Homo sapiens
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation	Homo sapiens
IRAK4 deficiency (TLR2/4)	Homo sapiens
Ligand-dependent caspase activation	Homo sapiens
MyD88 deficiency (TLR2/4)	Homo sapiens
MyD88-independent TLR4 cascade	Homo sapiens
MyD88:MAL(TIRAP) cascade initiated on plasma membrane	Homo sapiens