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Interleukin-6 receptor subunit beta

Summary

UniProt ID

Q00560

Gene Symbol

Il6st

Organism

Mus musculus (house mouse)

External Links

GlycoProtDB

GPDB0003842

GlyConnect

2412

GlyGen

Q00560

PubChem

Q00560

The O-GlcNAc Database

Q00560

O-GlcNAcAtlas

Q00560

Annotation

Keyword

3D-structure
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Gene Ontology (GO)

Displaying entries **1 - 10** of 18 in total

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GO Term
positive regulation of tyrosine phosphorylation of STAT protein
positive regulation of Notch signaling pathway
positive regulation of T cell proliferation
negative regulation of neuron apoptotic process
positive regulation of osteoblast differentiation
positive regulation of astrocyte differentiation
intestinal epithelial cell development
negative regulation of cytosolic calcium ion concentration
interleukin-27-mediated signaling pathway
interleukin-11-mediated signaling pathway

Displaying **all 10** entries
GO Term
neuronal cell body
receptor complex
cell body
membrane raft
interleukin-6 receptor complex
oncostatin-M receptor complex
external side of plasma membrane
neuronal cell body membrane
ciliary neurotrophic factor receptor complex
dendrite

Displaying entries **1 - 10** of 12 in total

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GO Term
cytokine receptor activity
cytokine binding
protein tyrosine kinase activator activity
identical protein binding
interleukin-6 receptor activity
leukemia inhibitory factor receptor activity
oncostatin-M receptor activity
interleukin-6 binding
ciliary neurotrophic factor receptor binding
interleukin-6 receptor binding

Annotation information from UniProt.

Sequence

MSAPRIWLAQALLFFLTTESIGQLLEPCGYIYPEFPVVQRGSNFTAICVLKEACLQHYYVNASYIVWKTNHAAVPREQVTVINRTTSSVTFTDVVLPSVQLTCNILSFGQIEQNVYGVTMLSGFPPDKPTNLTCIVNEGKNMLCQWDPGRETYLETNYTLKSEWATEKFPDCQSKHGTSCMVSYMPTYYVNIEVWVEAENALGKVSSESINFDPVDKVKPTPPYNLSVTNSEELSSILKLSWVSSGLGGLLDLKSDIQYRTKDASTWIQVPLEDTMSPRTSFTVQDLKPFTEYVFRIRSIKDSGKGYWSDWSEEASGTTYEDRPSRPPSFWYKTNPSHGQEYRSVRLIWKALPLSEANGKILDYEVILTQSKSVSQTYTVTGTELTVNLTNDRYVASLAARNKVGKSAAAVLTIPSPHVTAAYSVVNLKAFPKDNLLWVEWTPPPKPVSKYILEWCVLSENAPCVEDWQQEDATVNRTHLRGRLLESKCYQITVTPVFATGPGGSESLKAYLKQAAPARGPTVRTKKVGKNEAVLAWDQIPVDDQNGFIRNYSISYRTSVGKEMVVHVDSSHTEYTLSSLSSDTLYMVRMAAYTDEGGKDGPEFTFTTPKFAQGEIEAIVVPVCLAFLLTTLLGVLFCFNKRDLIKKHIWPNVPDPSKSHIAQWSPHTPPRHNFNSKDQMYSDGNFTDVSVVEIEANNKKPCPDDLKSVDLFKKEKVSTEGHSSGIGGSSCMSSSRPSISSNEENESAQSTASTVQYSTVVHSGYRHQVPSVQVFSRSESTQPLLDSEERPEDLQLVDSVDGGDEILPRQPYFKQNCSQPEACPEISHFERSNQVLSGNEEDFVRLKQQQVSDHISQPYGSEQRRLFQEGSTADALGTGADGQMERFESVGMETTIDEEIPKSYLPQTVRQGGYMPQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 4** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
43		17406563 22823882 23002422
83		17406563 22823882 23002422
157
225		22823882 23002422

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 6** entries
Pathway Name	Organism
IL-6-type cytokine receptor ligand interactions	Mus musculus
Interleukin-27 signaling	Mus musculus
Interleukin-35 Signalling	Mus musculus
Interleukin-6 signaling	Mus musculus
MAPK1 (ERK2) activation	Mus musculus
MAPK3 (ERK1) activation	Mus musculus

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

All Resources

Other Information

Tools

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Summary

External Links

Annotation

International Collaboration

Acknowledgements