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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mesothelin
Summary
- UniProt ID
- Q13421
- Gene Symbol
-
- MSLN
- MPF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell adhesion
- Cell membrane
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cell adhesion |
| cell-matrix adhesion |
| GO Term |
|---|
| extracellular region |
| Golgi apparatus |
| plasma membrane |
| membrane |
| endoplasmic reticulum lumen |
| cell surface |
| side of membrane |
Sequence
MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPLDLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTWSVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKTACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLSMQEALSGTPCLLGPGPVLTVLALLLASTLA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:10825 | essential hypertension | |
| DOID:1138 | spinal meningioma | |
| DOID:12265 | chronic salpingo-oophoritis | |
| DOID:12689 | acoustic neuroma | |
| DOID:1324 | lung cancer | |
| DOID:1325 | bronchus cancer | |
| DOID:1380 | endometrial cancer | |
| DOID:13832 | patent ductus arteriosus | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer |
