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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Mesothelin
Summary
- UniProt ID
- Q13421
- Gene Symbol
-
- MSLN
- MPF
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell adhesion
- Cell membrane
- Cleavage on pair of basic residues
- Direct protein sequencing
- Disulfide bond
- GPI-anchor
- Golgi apparatus
- Phosphoprotein
- Reference proteome
- Secreted
- Signal
- Gene Ontology (GO)
| GO Term |
|---|
| cell adhesion |
| cell-matrix adhesion |
| GO Term |
|---|
| extracellular region |
| Golgi apparatus |
| plasma membrane |
| membrane |
| endoplasmic reticulum lumen |
| cell surface |
| side of membrane |
Sequence
MALPTARPLLGSCGTPALGSLLFLLFSLGWVQPSRTLAGETGQEAAPLDGVLANPPNISSLSPRQLLGFPCAEVSGLSTERVRELAVALAQKNVKLSTEQLRCLAHRLSEPPEDLDALPLDLLLFLNPDAFSGPQACTRFFSRITKANVDLLPRGAPERQRLLPAALACWGVRGSLLSEADVRALGGLACDLPGRFVAESAEVLLPRLVSCPGPLDQDQQEAARAALQGGGPPYGPPSTWSVSTMDALRGLLPVLGQPIIRSIPQGIVAAWRQRSSRDPSWRQPERTILRPRFRREVEKTACPSGKKAREIDESLIFYKKWELEACVDAALLATQMDRVNAIPFTYEQLDVLKHKLDELYPQGYPESVIQHLGYLFLKMSPEDIRKWNVTSLETLKALLEVNKGHEMSPQAPRRPLPQVATLIDRFVKGRGQLDKDTLDTLTAFYPGYLCSLSPEELSSVPPSSIWAVRPQDLDTCDPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLKALSQQNVSMDLATFMKLRTDAVLPLTVAEVQKLLGPHVEGLKAEERHRPVRDWILRQRQDDLDTLGLGLQGGIPNGYLVLDLSMQEALSGTPCLLGPGPVLTVLALLLASTLA
Glycosylation Sites
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Post-translational modification: synthesis of GPI-anchored proteins | Homo sapiens |
| Post-translational protein phosphorylation | Homo sapiens |
| Regulation of IGF Activity by IGFBP | Homo sapiens |
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:1790 | malignant mesothelioma | |
| DOID:1793 | pancreatic cancer | |
| DOID:1974 | adenosarcoma | |
| DOID:2154 | nephroblastoma | |
| DOID:2394 | ovarian cancer | |
| DOID:2531 | hematologic cancer | |
| DOID:2568 | cervicitis | |
| DOID:2645 | benign mesothelioma | |
| DOID:2871 | endometrial carcinoma | |
| DOID:2893 | cervix carcinoma |
