PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Lactobacillus johnsonii | Unknown | unnamed ligand | Oligoglycosylceramides | Bovine buttermilk | Gal(b1-4)GlcNAc(b1-6)[Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
Mycoplasma pneumoniae | Adhesins | Fetuin | Glycoproteins | Bovine erythrocytes | Binding | 2470754 | |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | I-active Sialyl lactoisooctaosylceramide | Sialoglycosphingolipids | Bovine erythrocytes | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
Escherichia coli | S-fimbriae (SfaA) | Seminolipid (Sulfogalactosylglycerolipid) | Glycolipids | Brain endothelial cells | Gal(3SO4)(b1-1)-alkylacylglycerol | Binding | 8098039 |
Escherichia coli | S-fimbriae (SfaA) | Galactosylceramide (Galactocerebroside) | Monoglycosylceramides | Brain endothelial cells | Gal(b1-1)Cer | Binding | 8098039 |
Escherichia coli | S-fimbriae (SfaA) | Galactosyl sulfatide | Sulfoglycosphingolipids | Brain endothelial cells | Gal(3SO4)(b1-1)Cer | Binding | 8098039 |
Escherichia coli | S-fimbriae (SfaA) | Lactosylceramide (Lactocerebroside) | Diosylceramides | Brain endothelial cells | Gal(b1-4)Glc(b1-1)Cer | Binding | 8098039 |
Clostridium tetani | Tetanus toxin | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
Clostridium tetani | Unknown | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
Clostridium tetani | Tetanus toxin | GT1b | Trisialoglycosphingolipids | Brain membrane | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
Clostridium tetani | Unknown | GT1b | Trisialoglycosphingolipids | Brain membrane | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
Pasteurella haemolytica | 68-kDa proteins | N-Acetylglucosamine | Monosaccharides | Bronchial lavages of sheep with pneumonic pasteurelosis | GlcNAc | Binding | 10570221 |
Pasteurella haemolytica | 68-kDa proteins | N-Acetylneuraminic acid | Monosaccharides | Bronchial lavages of sheep with pneumonic pasteurelosis | NeuAc | Binding | 10570221 |
Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Binding | 9712794 |
Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Binding | 9712794 |
Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:2 | Not Binding | 9712794 |
Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:1 | Binding | 9712794 |
Actinomyces naeslundii | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:1 | Not Binding | 9712794 |
Actinomyces odontolyticus | Type 2-fimbriae | β-linked galactosamine | Saccharides | Buccae | GalNAc(b 2:1 | Not Binding | 9712794 |
Borrelia garinii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
Borrelia garinii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
Borrelia garinii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
Borrelia garinii | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
Borrelia burgdorferi | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 | |
Borrelia burgdorferi | Unknown | Heparan sulfate | Glycosaminoglycans | C6 glioma cells, EA-Hy926 cells | Binding | 10085013 |
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Last updated: August 19, 2024