PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
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Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Polyoma virus | SV40 | GM1 | Monosialoglycosphingolipids | (broad range) | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
Staphylococcus aureus | SSL5 | Sialyl Lewis x (SLex) antigen | Oligosaccharides | (broad range) | NeuAc(a2-3)Gal(b1-4) | Binding | 18809496 |
Staphylococcus aureus | SSL11 | Sialyl Lewis x (SLex) antigen | Oligosaccharides | (broad range) | NeuAc(a2-3)Gal(b1-4) | Binding | 18809496 |
Polyoma virus | Capsid VP1 | GD1a-GT1b analog | Sialoglycosphingolipids | (broad range) | Binding | 18809496 | |
Pseudomonas aeruginosa | LecB | alpha-methyl-fucoside | Monosaccharides | A549 cells | Binding | 19237519 | |
Pseudomonas aeruginosa | LecA | Alpha-methyl-galactoside | Monosaccharides | A549 cells | Binding | 19237519 | |
Escherichia coli | PrsG (class III) G adhesins | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Acute cystitis patients | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | |
Escherichia coli | P-fimbriae | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Acute cystitis patients | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | |
Pseudomonas aeruginosa | PA-IIL | Lewis a (Lea) (GSL) | Glycosphingolipids | Airways | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
Influenza virus | Hemagglutinin | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
Influenza virus | Hemagglutinin H1(1934) | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
Paramyxovirus | Hemagglutinin H1(1934) | Human and avian receptors containing sialylated glycoconjugates | Glycoconjugates | Airways | Binding | 18809496 | |
Pseudomonas aeruginosa | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Apical membrane of cystic fibrosis epithelia | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7708767 |
Staphylococcus aureus | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Apical membrane of cystic fibrosis epithelia, Patients with pneumonia | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7708767 |
Influenza virus | Residues 226 (glutamine) and 228 (glycine) | Sialic acid linked to α2,3Galβ1,3GalNAc | Oligosaccharides | Avian/equine isolates | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 7975212 |
Coronavirus | Unknown | MHVR (murine member of the carcinoembryonic antigen family of glycoproteins) | Glycoproteins | BHK-21 cells | Binding | 1318394 | |
Foot-and-mouth disease virus | VP1 protein (RGD motif) | αvβ3 Integrin | Glycoproteins | BHK-21/LLC-MK2/HeLa/BK-LF | Binding | 7533862 | |
Escherichia coli | Type 1-pili | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
Escherichia coli | FimCH-chaperone-adhesin complex | D-Mannose | Monosaccharides | Bladder epithelium | Man | Binding | 12010488 |
Neisseria meningitidis | Type 4-pili | Thyroglobulin containing N-linked complex and hybrid (oligomannosidic) glycans | Glycoproteins | Bovine | Binding | 16177210 | |
Bordetella pertussis | Pertussis toxin | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
Bordetella pertussis | Unknown | Fetuin | Glycoproteins | Bovine | Binding | 14532091 | |
Influenza virus | Unknown | Gangliosides | Sialoglycosphingolipids | Bovine brain | Binding | 1740131 | |
Lactobacillus johnsonii | Unknown | unnamed ligand | Sialoglycosphingolipids | Bovine buttermilk | Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | unnamed ligand | Sialoglycosphingolipids | Bovine buttermilk | Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
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Last updated: December 9, 2024