Pathogen Adherence to Carbohydrate Database (PACDB)

PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.

Source Last Updated
Pathogen Adherence to Carbohydrate Database (PACDB) June 1, 2016
Displaying entries 1 - 25 of 1840 in total
Species Pathogen Adherence Molecule Ligand Name Ligand Feature Target Source ▲ Glycan Sequence Binding PubMed ID
Polyoma virus SV40 GM1 Monosialoglycosphingolipids (broad range) Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer Binding 18809496
Staphylococcus aureus SSL5 Sialyl Lewis x (SLex) antigen Oligosaccharides (broad range) NeuAc(a2-3)Gal(b1-4) Binding 18809496
Staphylococcus aureus SSL11 Sialyl Lewis x (SLex) antigen Oligosaccharides (broad range) NeuAc(a2-3)Gal(b1-4) Binding 18809496
Polyoma virus Capsid VP1 GD1a-GT1b analog Sialoglycosphingolipids (broad range) Binding 18809496
Pseudomonas aeruginosa LecB alpha-methyl-fucoside Monosaccharides A549 cells Binding 19237519
Pseudomonas aeruginosa LecA Alpha-methyl-galactoside Monosaccharides A549 cells Binding 19237519
Escherichia coli PrsG (class III) G adhesins Gb5 (Forssman glycolipid) Oligoglycosylceramides Acute cystitis patients GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer Binding
Escherichia coli P-fimbriae Gb5 (Forssman glycolipid) Oligoglycosylceramides Acute cystitis patients GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer Binding
Pseudomonas aeruginosa PA-IIL Lewis a (Lea) (GSL) Glycosphingolipids Airways Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer Binding 18809496
Influenza virus Hemagglutinin Human and avian receptors containing sialylated glycoconjugates Glycoconjugates Airways Binding 18809496
Influenza virus Hemagglutinin H1(1934) Human and avian receptors containing sialylated glycoconjugates Glycoconjugates Airways Binding 18809496
Paramyxovirus Hemagglutinin H1(1934) Human and avian receptors containing sialylated glycoconjugates Glycoconjugates Airways Binding 18809496
Pseudomonas aeruginosa Unknown Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) Oligoglycosylceramides Apical membrane of cystic fibrosis epithelia Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer Binding 7708767
Staphylococcus aureus Unknown Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) Oligoglycosylceramides Apical membrane of cystic fibrosis epithelia, Patients with pneumonia Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer Binding 7708767
Influenza virus Residues 226 (glutamine) and 228 (glycine) Sialic acid linked to α2,3Galβ1,3GalNAc Oligosaccharides Avian/equine isolates NeuAc(a2-3)Gal(b1-3)GalNAc Binding 7975212
Coronavirus Unknown MHVR (murine member of the carcinoembryonic antigen family of glycoproteins) Glycoproteins BHK-21 cells Binding 1318394
Foot-and-mouth disease virus VP1 protein (RGD motif) αvβ3 Integrin Glycoproteins BHK-21/LLC-MK2/HeLa/BK-LF Binding 7533862
Escherichia coli Type 1-pili D-Mannose Monosaccharides Bladder epithelium Man Binding 12010488
Escherichia coli FimCH-chaperone-adhesin complex D-Mannose Monosaccharides Bladder epithelium Man Binding 12010488
Neisseria meningitidis Type 4-pili Thyroglobulin containing N-linked complex and hybrid (oligomannosidic) glycans Glycoproteins Bovine Binding 16177210
Bordetella pertussis Pertussis toxin Fetuin Glycoproteins Bovine Binding 14532091
Bordetella pertussis Unknown Fetuin Glycoproteins Bovine Binding 14532091
Influenza virus Unknown Gangliosides Sialoglycosphingolipids Bovine brain Binding 1740131
Lactobacillus johnsonii Unknown unnamed ligand Sialoglycosphingolipids Bovine buttermilk Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer Not Binding 11087711
Helicobacter pylori Neutrophil-activating proteins (150-kDa) unnamed ligand Sialoglycosphingolipids Bovine buttermilk Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)Glc(b1-1)Cer Not Binding 9228091

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