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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Vibrio cholerae | Cholera toxin | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Escherichia coli | Heat-labile enterotoxin | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Unknown | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Rotavirus | Unknown | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 11160731 | |
| Escherichia coli | Unknown | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Clostridium tetani | Tetanus toxin | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Rotavirus | Unknown | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Clostridium tetani | Unknown | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Helicobacter pylori | 35S-labeled or 125I-labeled proteins | GgO4 (de-N-acylated) | Oligoglycosylceramides | Mouse small intestine | Gal(b1-3)GalNH2(b1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9499377 |
| Pseudomonas aeruginosa | Unknown | unnamed ligand | Oligosaccharides | Respiratory tract | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc | Binding | 16564136 |
| Propionibacterium granulosum | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2452754 |
| Escherichia coli | F1C | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11877427 |
| Neisseria gonorrhoeae | Lectin-like proteins (adhesin) | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gonorrhoeae patients | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2468365 |
| Propionibacterium granulosum | Lectin-like proteins (adhesin) | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human skin | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2468365 |
| Actinomyces viscosus | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 11087711 |
| Helicobacter pylori | Neutrophil-activating proteins (150-kDa) | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 9228091 |
| Shigella dysenteriae | B subunit | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces naeslundii | Unknown | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Human meconium | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Helicobacter mustelae | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter bilis | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter pylori | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter hepaticus | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Helicobacter felis | Lectin-hemagglutinin adhesins | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 12704182 | |
| Vibrio cholerae | Cholera toxin | Lc4Cer (Lactotetraosylceramide) | Oligoglycosylceramides | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 |
