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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source ▲ | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Lactobacillus casei | Unknown | Gb5 (Forssman glycolipid) | Oligoglycosylceramides | Intestinal tract | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 8912650 |
| Clostridium botulinum | Progenitor toxin (type A) | Lactose | Disaccharides | Intestine-407 cells | Gal(b1-4)Glc | Binding | 15850798 |
| Clostridium botulinum | Progenitor toxin (type A) | N-acetyllactosamine (LacNAc) | Disaccharides | Intestine-407 cells | Gal(b1-4)GlcNAc | Binding | 15850798 |
| Clostridium botulinum | Unknown | Lactose | Disaccharides | Intestine-407 cells | Gal(b1-4)Glc | Binding | 15850798 |
| Clostridium botulinum | Unknown | N-acetyllactosamine (LacNAc) | Disaccharides | Intestine-407 cells | Gal(b1-4)GlcNAc | Binding | 15850798 |
| Escherichia coli | Pyelonephritic adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Kidney | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 18809496 |
| Escherichia coli | S-fimbriae | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
| Escherichia coli | SfaS | NeuAcα3Galβ-containing glycoproteins | Glycoproteins | Lumenal surfaces of the vascular endothelium in the neonatal rat brain | NeuAc(a2-3)Gal(b | Binding | 15973004 |
| Pseudomonas aeruginosa | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Lung | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Pseudomonas cepacia | Unknown | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Lung | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Pseudomonas aeruginosa | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Lung | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Pseudomonas cepacia | Unknown | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Lung | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3124753 |
| Rotavirus | Unknown | Sialic acid | Monosaccharides | MA-104 cells | Binding | 10659372 | |
| Bordetella pertussis | FHA (tail region) | Complement receptor 3 (CR3) integrins | Glycoproteins | Macrophages | Binding | 11348687 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Vaccinia virus | A27L proteins | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Vaccinia virus | A27L proteins | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Vaccinia virus | A27L proteins | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Vaccinia virus | A27L proteins | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Borrelia burgdorferi | BBK32 | Dermatan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 16368999 | |
| Myxoma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
| Myxoma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 |
