PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
Source | Last Updated |
---|---|
Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
---|---|---|---|---|---|---|---|
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Dermatan sulfate | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-A) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Rabbit fibroma virus | Unknown | Heparan sulfate | Glycosaminoglycans | Mammalian cell surface | Binding | 9445060 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-A) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-A) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Borrelia burgdorferi | Unknown | Chondroitin 6-sulfate (C-6S) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialic acid | Monosaccharides | Human neutrophils | Binding | 15689619 | |
Streptococcus pneumoniae | CBPs (choline-binding proteins) | Sialic acid | Monosaccharides | Cytokine-activated cells | Binding | 12640357 | |
Parvovirus | Unknown | Sialic acid (both O- and N-linked) | Monosaccharides | Nucleated bovine cells | Binding | 15269359 | |
Rabies virus | Unknown | Sialic acid | Monosaccharides | Chicken embryo related cells | Binding | 3583664 | |
Helicobacter pylori | Adhesins | Five-sugar monosialoganglioside | Monosialoglycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
Haemophilus influenzae | HMW2 | Oligosaccharides rich in sialic acid | Oligosaccharides | Human epithelial cells | Binding | 12640357 | |
Haemophilus influenzae | HMW1 | Oligosaccharides rich in sialic acid | Oligosaccharides | Human epithelial cells | Binding | 12640357 | |
Helicobacter pylori | Adhesins | Gangliosides | Sialoglycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
Polyoma virus | Capsid VP1 | GD1a-GT1b analog | Sialoglycosphingolipids | (broad range) | Binding | 18809496 | |
Bordetella pertussis | Pertussis toxin | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
Bordetella pertussis | PT (subunit S3 of B oligomer) | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
Clostridium botulinum | BoNT/B | GT1b (complex with synaptotagmin II) | Trisialoglycosphingolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 | |
Clostridium tetani | Tetanus toxin (Hc fragment) | GT1b analog | Trisialoglycosphingolipids | Synapse | Binding | 18809496 | |
Clostridium botulinum | Botulinum neurotoxin | GT1b (complex with synaptotagmin II) | Trisialoglycosphingolipids | Presynaptic membrane of neuromuscular junction | Binding | 7527117 |
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Last updated: December 9, 2024