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MIRAGE
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Borrelia burgdorferi | Unknown | Heparan sulfate (fraction: HS-D) | Glycosaminoglycans | Vero cells | Not Binding | 9826395 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | VP1 (RGD peptide) | Heparan sulfate (independent of expression of αvβ3 Integrin on cell-sulface) | Glycosaminoglycans | Extracellular matrix (ECM) | Binding | 9557639 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate A | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Foot-and-mouth disease virus | Natural ligand of integrin [alpha]v[beta]3 | Chondroitin sulfate C | Glycosaminoglycans | Extracellular matrix (ECM) | Not Binding | 8764038 | |
| Streptococcus pneumoniae | CBPs (choline-binding proteins) | Sialic acid | Monosaccharides | Cytokine-activated cells | Binding | 12640357 | |
| Helicobacter pylori | SabA (sialic acid-binding adhesin) | Sialic acid | Monosaccharides | Human neutrophils | Binding | 15689619 | |
| Rabies virus | Unknown | Sialic acid | Monosaccharides | Chicken embryo related cells | Binding | 3583664 | |
| Parvovirus | Unknown | Sialic acid (both O- and N-linked) | Monosaccharides | Nucleated bovine cells | Binding | 15269359 | |
| Escherichia coli | SfaI-S | Sialic acid | Monosaccharides | Epithelial cells, Extracellular matrix (ECM) | Binding | 10732678 | |
| Streptococcus gordonii | Adhesins | Sialic acid | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Binding | 11035744 | |
| Streptococcus gordonii | Hsa | Sialic acid | Monosaccharides | Human oral cavity (erythrocytes and polymorphonuclear leukocytes) | Binding | 16177339 | |
| Streptococcus pneumoniae | CbpA; SpsA; PbcA; PspC (CBPs) | Sialic acid | Monosaccharides | Cytokine activated epithelial and endothelial cells | Binding | 10341176 | |
| Reovirus | sigma 1 proteins | Sialic acid | Monosaccharides | Murine intestine, Murine spleen, Murine liver, Murine brain, Human cholangiocarcinoma cells | Binding | 12813018 | |
| Bordetella pertussis | Iron-induced surface-exposed proteins | Sialic acid | Monosaccharides | Respiratory epithelial cells (A549) | Binding | 17727651 | |
| Plasmodium falciparum | Unknown | Sialic acid | Monosaccharides | Glycophorins A/B on the erythrocyte membrane | Binding | 3308959 | |
| Rotavirus | Unknown | Sialic acid | Monosaccharides | MA-104 cells | Binding | 10659372 | |
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Epithelial cells of small intestine | Binding | 16511112 | |
| Bordetella pertussis | PT (subunit S3 of B oligomer) | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 | |
| Helicobacter pylori | Adhesins | Gangliosides | Sialoglycosphingolipids | Human leukocytes, Human neutrophils | Binding | 10569742 | |
| Bordetella pertussis | Pertussis toxin | Gangliosides | Sialoglycosphingolipids | Human alveolar macrophages | Binding | 1729677 |
