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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Neisseria meningitidis | Type 4-pili | Agglutinin glycoproteins containing O-/N-linked (poly)lactosamine and hybrid oligosaccharides | Glycoproteins | Human saliva | Binding | 16177210 | |
| Escherichia coli | Type G-fimbriae | N-Acetylglucosamine | Monosaccharides | GlcNAc | Binding | 2885220 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GD1a | Disialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GD1b | Disialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GM1 | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | GT1b | Trisialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 3804448 | |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | N-Acetylgalactosamine | Monosaccharides | Polymorphonuclear leukocytes (PMNs) | GalNAc | Binding | 7790078 |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | Galactose | Monosaccharides | Polymorphonuclear leukocytes (PMNs) | Gal | Binding | 7790078 |
| Actinomyces naeslundii | Type-2 fimbrial lectins (130-kDa glycoprotein) | unnamed ligand | Oligosaccharides | Polymorphonuclear leukocytes (PMNs) | Gal(b1-3)GalNAc | Binding | 7790078 |
| Actinomyces naeslundii | Unknown | GD1b | Disialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Clostridium tetani | Unknown | GD1b | Disialoglycosphingolipids | Brain membrane | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 6257717 |
| Norovirus | Unknown | Sialylated type 2 chain conjugates (S-type 2-HSA) | Glycoproteins | Human serum albumin | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Norovirus | Unknown | Sialyl Lewis x (SLex-HSA) | Glycoproteins | Human serum albumin | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(c)-APD | Binding | 19054801 |
| Influenza virus | Unknown | GM3(NeuAc) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Influenza virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Sendai virus | Unknown | Sialyl-3-Paragloboside (S-3-PG; α2,3-sialylparagloboside) | Monosialoglycosphingolipids | Granulocytes | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 8823909 |
| Actinomyces naeslundii | Unknown | GM1 | Monosialoglycosphingolipids | Human brain | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 2358461 |
| Helicobacter pylori | Unknown | unnamed ligand | Oligosaccharides | Stomach | NeuAc(a2-3)Gal(b1-4)GlcNAc | Binding | 16564136 |
| Polyoma virus | Unknown | Sialylated oligosaccharides | Oligosaccharides | Erythrocytes | NeuAc(a2-3)Gal(b1-3)GalNAc | Binding | 6316632 |
| Polyoma virus | Unknown | unnamed ligand | Oligosaccharides | Murine small plaque | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc | Binding | 8574698 |
| Reovirus | Unknown | Sialic acid (α2,6) | Saccharides | Most organs including the central nervous system/heart/liver | NeuAc(a2-6) | Binding | 18216114 |
| Mycoplasma pneumoniae | Unknown | Sulfo-lactosylceramide (SM3) | Sulfoglycosphingolipids | Human colon adenocarcinoma cells (WiDr ) | HSO3(-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2470753 |
| Lactobacillus casei | Unknown | Sulfatide (CSE) | Sulfoglycosphingolipids | Intestinal tract | HSO3(-3)Gal(b1-1)Cer | Binding | 8912650 |
