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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Legionella pneumophila | Adhesins | GM3(NeuAc) | Monosialoglycosphingolipids | Human epithelial cells (respiratory tract) | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 14687561 |
| Legionella pneumophila | Adhesins | GM1 | Monosialoglycosphingolipids | Human epithelial cells (respiratory tract) | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 14687561 |
| Legionella pneumophila | Adhesins | GM2(NeuAc) | Monosialoglycosphingolipids | Human epithelial cells (respiratory tract) | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 14687561 |
| Helicobacter pylori | Adhesins | GM3(NeuAc) | Monosialoglycosphingolipids | Human gastric mucosa | NeuAc(a2-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2037054 |
| Mycoplasma pneumoniae | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Erythrocytes | HSO3(-3)Gal(b1-1)Cer | Binding | 2470754 |
| Helicobacter pylori | Adhesins | Sulfatide (CSE) | Sulfoglycosphingolipids | Human gastric mucosa | HSO3(-3)Gal(b1-1)Cer | Binding | 2037054 |
| Streptococcus gordonii | Adhesins | PMN (polymorphonuclear leukocytes) surface glycoproteins in the presence of sialic acid | Glycoproteins | Human peripheral blood buffy coat cells | Binding | 11035744 | |
| Streptococcus gordonii | Adhesins | Sialic acid | Monosaccharides | HL-60 promyelocytic leukemia cell line, Leukosialin (CD43) | Binding | 11035744 | |
| Histoplasma capsulatum | Adhesins | Lactosylceramide (Lactocerebroside) | Diosylceramides | Phagocytes | Gal(b1-4)Glc(b1-1)Cer | Binding | 19547878 |
| Neisseria gonorrhoeae | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
| Legionella pneumophila | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | Human epithelial cells (respiratory tract) | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 14687561 |
| Legionella pneumophila | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Human epithelial cells (respiratory tract) | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 14687561 |
| Escherichia coli | Adhesins | Gb4 (Globoside; Globotetraose; P antigen) | Oligoglycosylceramides | Human erythrocytes, Human uroepithelial cells | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 7037645 |
| Neisseria gonorrhoeae | Adhesins | unnamed ligand | Oligosaccharides | Mucos membranes of the genitourinary tract/rectum/oropharynx/conjunctiva | Gal(b1-4)GlcNAc(b1-4)Gal(b1-4)Glc | Binding | 2115881 |
| Legionella pneumophila | Adhesins | unnamed ligand | Oligosaccharides | Human epithelial cells (respiratory tract) | Gal(b1-4)GlcNAc | Binding | 14687561 |
| Pseudomonas aeruginosa | Adhesins | MUC1 mucin | Glycoproteins | Surface of chinese hamster ovary (CHO) cells | Binding | 11133508 | |
| Mycoplasma pneumoniae | Adhesins | Fetuin | Glycoproteins | Bovine erythrocytes | Binding | 2470754 | |
| Mycoplasma pneumoniae | Adhesins | Laminin | Glycoproteins | Murine Engelbreth Holm Swarm tumor, Murine erythrocytes | Binding | 2470754 | |
| Mycoplasma pneumoniae | Adhesins | hCG (human chorionic gonadotropin) | Glycoproteins | Erythrocytes | Binding | 2470754 | |
| Streptococcus gordonii | Adhesins | Fetuin | Glycoproteins | HL-60 promyelocytic leukemia cell line | Binding | 11035744 | |
| Bordetella parapertussis | Adhesins | terminal Gal(3SO4) β1- residues | Sulfoglycosphingolipids | Gal(3SO4)(b | Binding | 1918002 | |
| Pseudomonas aeruginosa | Adhesins | Asialo-GM2 (Gangliotriosylceramide; GgO3) | Oligoglycosylceramides | GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 | |
| Pseudomonas aeruginosa | Adhesins | nLc4Cer (Neolactotetraosylceramide; Paragloboside) | Oligoglycosylceramides | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 | |
| Bordetella parapertussis | Adhesins | Asialo GM1 (Gangliotetraosylceramide; Gg4; GA1) | Oligoglycosylceramides | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1)Cer | Binding | 1918002 | |
| Neisseria gonorrhoeae | Adhesins | Lactotriaosylceramide (Lc3) | Oligoglycosylceramides | GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Binding | 2115881 |
