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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule ▲ | Ligand Name | Ligand Feature | Target Source | Glycan Sequence | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Influenza virus | Unknown | Glycoproteins | Glycoproteins | Rat serum | Binding | 1740131 | |
| Staphylococcus aureus | Unknown | MUC16 mucin | Glycoproteins | Human corneal-limbal epithelial(HCLE) cells | Binding | 17898272 | |
| Reovirus | Unknown | Junctional adhesion molecule A (JAM-A) | Glycoproteins | Most organs including the central nervous system/heart/liver | Binding | 18216114 | |
| Borrelia burgdorferi | Unknown | Heparin (N-desulfated, N-acetylated) | Glycosaminoglycans | Vero cells | Binding | 9826395 | |
| Human immunodeficiency virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human T cells | Binding | 9420059 | |
| Chlamydia trachomatis | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | HeLa cells | Binding | 9420059 | |
| Herpes simplex virus | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human cervical cells | Binding | 9420059 | |
| Neisseria gonorrhoeae | Unknown | NAC-heparin (non-anticoagulant heparin) | Glycosaminoglycans | Human epithelial cells | Binding | 9420059 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Human erythrocytes, Human leukocytes, Human placenta | Binding | 9169796 | |
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Rat small intestine, Wild boar intestine, Monkey intestine | Binding | 9169796 | |
| Actinomyces odontolyticus | Unknown | unknown carbohydrate ligand | Saccharides | Tongue | Binding | 9712794 | |
| Clostridium botulinum | Unknown | Complex of synaptotagmin II and ganglioside GT1b or GD1a | Glycoconjugates | Binding | 9712688 | ||
| Human immunodeficiency virus | Unknown | Cluster of differentiation 4 (CD4) | Glycoproteins | Binding | 15973004 | ||
| Helicobacter pylori | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Binding | 12628483 | ||
| Helicobacter pylori | Unknown | Ganglio glycolipids | Glycosphingolipids | Binding | 16088272 | ||
| Influenza virus | Unknown | PGCs (polyglycosyl ceramides) | Glycosphingolipids | Binding | 12628483 | ||
| Hepatitis virus | Unknown | N-linked glycans | N-glycans | Binding | 11530212 | ||
| Campylobacter upsaliensis | Unknown | Phosphatidylserine (PS) | Non-glycosylated Lipids | Binding | 8926069 | ||
| Semliki forest virus | Unknown | Sphingomyelin | Non-glycosylated Lipids | Binding | 8574698 | ||
| Plasmodium falciparum | Unknown | N-linked oligosaccharides of glycophorins | Oligosaccharides | Binding | 8574698 | ||
| Rotavirus | Unknown | GD2(NeuGc) | Disialoglycosphingolipids | GalNAc(b1-4)[NeuGc(a2-8)NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Clostridium tetani | Unknown | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7527546 | |
| Rotavirus | Unknown | GM1(NeuGc) | Monosialoglycosphingolipids | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11160731 | |
| Influenza virus | Unknown | NeuAc3-Lc4Cer (Sialyl lactotetraosylceramide) | Sialoglycosphingolipids | NeuAc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 7870741 | |
| Norovirus | Unknown | Blood group H antigen | Disaccharides | Saliva | Fuc(a1-2)Gal | Not Binding | 18701592 |
