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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Newcastle disease virus | HN(hemagglutinin-neuraminidase) glycoproteins | Sialic acid | Monosaccharides | Binding | 17205603 | ||
| Sendai virus | "HN (hemagglutinin neuraminidase), F (fusion protein)" | Sialic acid | Monosaccharides | Binding | 8574698 | ||
| Rotavirus | VP8 (galectin) | Sialic acid(2-O-methyl-α-Neu5Ac (Neu5Ac2Me)) | Monosaccharides | Binding | 17306299 | ||
| Rotavirus | VP8 (spike protein) | Sialic acid | Monosaccharides | Binding | 17277447 | ||
| Rotavirus | VP8 | Sialic acid | Monosaccharides | Binding | 18540062 | ||
| Helicobacter pylori | Unknown | Sialic acid | Monosaccharides | Binding | 16088272 | ||
| Rotavirus | TLP (Triple-layered virus particles) | Gangliosides | Sialoglycosphingolipids | Binding | 10659372 | ||
| Borrelia burgdorferi | "OspA, OspB, OspC" | Gangliosides | Sialoglycosphingolipids | Binding | 16299269 | ||
| Influenza virus | Unknown | Neuraminic acid-containing sialoglycosphingolipids | Sialoglycosphingolipids | Binding | 15973004 | ||
| Influenza virus | SNA lectins | Minor NeuAcα6-containing molecules | Glycoconjugates | Human leukocytes | Binding | 11030743 | |
| Escherichia coli | Type 1-fimbriae | Glycoside p-nitrophenyl alpha-D-mannopyranoside | Glycoconjugates | Patient with urinary tract infection | Binding | 6138149 | |
| Pseudomonas aeruginosa | Type 4-pili | Surface-localized glycoconjugates (non-sialylated GSL and glycoproteins) | Glycoconjugates | Human epithelial cells | Binding | 9224879 | |
| Adenovirus | Fibre proteins | HSA glycoconjugates | Glycoproteins | Human corneal epithelial(HEC) cells | Binding | 15678425 | |
| Entamoeba histolytica | Transmembrane heavy subunit (Hgl; 170-kDa) disulfide linked to a GPI-anchored light subunit (Lgl; 31-to 35-kDa). | β-2 and β-7 integrins | Glycoproteins | Intestinal cells | Binding | 15322032 | |
| Sporothrix schenckii | Yeast cells and conidia | Fibronectin | Glycoproteins | Extracellular matrix (ECM) | Binding | 11598061 | |
| Paracoccidioides brasiliensis | Adhesins | Fibronectin | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Paracoccidioides brasiliensis | Adhesins | Fibrinogen | Glycoproteins | Human type II alveolar cells (A549) | Binding | 18083324 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Streptococcus pyogenes | Protein F (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory epithelial cells | Binding | 1385871 | |
| Neisseria meningitidis | Type 4-pili | Agglutinin glycoproteins containing O-/N-linked (poly)lactosamine and hybrid oligosaccharides | Glycoproteins | Human saliva | Binding | 16177210 | |
| Leptospira interrogans | Lsa24 | Laminin | Glycoproteins | Extracellular matrix (ECM) | Binding | 16954400 | |
| Coronavirus | Unknown | MHVR (murine member of the carcinoembryonic antigen family of glycoproteins) | Glycoproteins | BHK-21 cells | Binding | 1318394 | |
| Streptococcus pyogenes | Sfbl (Antigen I/II) | Fibronectin | Glycoproteins | Respiratory endothelial cells | Binding | 10341176 | |
| Mycoplasma pneumoniae | Adhesins | Laminin | Glycoproteins | Murine Engelbreth Holm Swarm tumor, Murine erythrocytes | Binding | 2470754 | |
| Mycoplasma pneumoniae | Adhesins | hCG (human chorionic gonadotropin) | Glycoproteins | Erythrocytes | Binding | 2470754 |
