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Pathogen Adherence to Carbohydrate Database (PACDB)
PACDB provides the information on pathogens (e.g. bacteria, fungus, toxin and virus) adhering to carbohydrates expressed on the cell surface of host animals or plants.
| Source | Last Updated |
|---|---|
| Pathogen Adherence to Carbohydrate Database (PACDB) | June 1, 2016 |
| Species | Pathogen Adherence Molecule | Ligand Name | Ligand Feature | Target Source | Glycan Sequence ▲ | Binding | PubMed ID |
|---|---|---|---|---|---|---|---|
| Norovirus | Unknown | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 18599458 | |
| Streptococcus pneumoniae | FcsSBP (fucose solute-binding protein) | Blood group B antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal | Binding | 19285508 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Human serum albumin | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 19054801 |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Binding | 18701592 | |
| Norovirus | Unknown | Blood group B antigen (B-tri-HSA) | Glycoproteins | Gal(a1-3)[Fuc(a1-2)]Gal(b)-O-APE | Not Binding | 18701592 | |
| Vibrio cholerae | Cholera toxin | B-GM1 | Monosialoglycosphingolipids | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Vibrio cholerae | Unknown | B-GM1 | Monosialoglycosphingolipids | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1)Cer | Binding | 7527546 | |
| Helicobacter pylori | BabA (blood group antigen binding adhesin) | Blood group B-Lewis b (BLeb) antigen | Oligosaccharides | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc | Binding | 15273394 | |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Various sources | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Various sources | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Lactobacillus johnsonii | Unknown | B6 type 2 glycosphingolipid (B6-2) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 11087711 |
| Shigella dysenteriae | B subunit | B6 type 2 glycosphingolipid (B6-2) | Oligoglycosylceramides | Human erythrocytes | Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 3543013 |
| Actinomyces viscosus | Unknown | unnamed ligand | Oligoglycosylceramides | Various sources | Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Actinomyces naeslundii | Unknown | unnamed ligand | Oligoglycosylceramides | Various sources | Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1)Cer | Not Binding | 2358461 |
| Escherichia coli | PapG | alpha-D-galactopyranosyl-(1-4)-beta-D-galactopyranose | Disaccharides | Uroepithelial cells | Gal(a1-4)Gal | Binding | 2886993 |
| Escherichia coli | P-fimbriae | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Pyelonephritis patients | Gal(a1-4)Gal | Binding | 8574698 |
| Escherichia coli | Verotoxin (1; B-subunit) | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Escherichia coli | Unknown | CD77 (Globotriaosylceramide; Gb3) | Oligoglycosylceramides | Germinal center B lymphocytes, Burkitt's lymphoma cells | Gal(a1-4)Gal | Binding | 7516406 |
| Streptococcus suis | PO | unnamed ligand | Oligosaccharides | human erythrocytes | Gal(a1-4)Gal | Binding | 7499414 |
| Streptococcus suis | PN | unnamed ligand | Oligosaccharides | human erythrocytes | Gal(a1-4)Gal | Binding | 7499414 |
| Pseudomonas aeruginosa | PA-IL (51-kDa) | Galactose-alpha-1,4-galactose | Disaccharides | Gal(a1-4)Gal | Binding | 15049333 | |
| Escherichia coli | PrsG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Escherichia coli | PapG | Gal alpha 1-4 Gal-containing glicolipids | Glycolipids | Gal(a1-4)Gal | Binding | 12640357 | |
| Streptococcus suis | Adhesins | P1 antigen (GSL) | Glycosphingolipids | Gal(a1-4)Gal | Binding | 7961660 |
