Sema4D induced cell migration and growth-cone collapse

Summary
Species
Caenorhabditis elegans
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
RHOA/B/C:GTPActivated ROCK:RhoA/B/C:GTPROCK1,ROCK2ROCKiROCK1,ROCK2:ROCKiSEMA4D dimerSEMA4D:ERBB2:p-Y-PLXNB1ATPPlexin-B1:ErbB2ADPrhgf-1SEMA4D:ERBB2:p-Y-PLXNB1:RND1:ARHGEF11,ARHGEF12SEMA4D:ERBB2:p-Y-PLXNB1:RND1GTPGDPRhoA,B,C:GDP
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
O45657 Plexin-2
  • plx-2
view
P24348 Receptor tyrosine-protein kinase let-23
  • kin-7
  • let-23
view
Q17330 Semaphorin-1A
  • sema-1a
  • smp-1
view
Q95XP4 Semaphorin-2A
  • mab-20
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025