Heme degradation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
ferrohemeBVH2OFe2+O2COTPNHTPNBILBILALBBIL:ALBBIL:GSTA1, FABP1GSTA1, FABP1BILUDP-GlcAUDPBMGBDGBMG,BDGBMG,BDGATPBMG,BDGPiADPBDGTPNH2OGlcATPNHelectron acceptorelectron acceptorD-UBGNSTBNUBN
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 9 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P02768 Albumin
  • ALB
view
P22309 UDP-glucuronosyltransferase 1A1
  • GNT1
  • UGT1
  • UGT1A1
view
P22310 UDP-glucuronosyltransferase 1A4
  • GNT1
  • UGT1
  • UGT1A4
view
P30519 Heme oxygenase 2
  • HMOX2
  • HO2
view
P33527 Multidrug resistance-associated protein 1
  • ABCC1
  • MRP
  • MRP1
view
Q92887 ATP-binding cassette sub-family C member 2
  • ABCC2
  • CMOAT
  • CMOAT1
  • CMRP
  • MRP2
view
Q9NPD5 Solute carrier organic anion transporter family member 1B3
  • LST2
  • OATP1B3
  • OATP8
  • SLC21A8
  • SLCO1B3
view
Q9UNQ0 Broad substrate specificity ATP-binding cassette transporter ABCG2
  • ABCG2
  • ABCP
  • BCRP
  • BCRP1
  • MXR
view
Q9Y6L6 Solute carrier organic anion transporter family member 1B1
  • LST1
  • OATP1B1
  • OATP2
  • OATPC
  • SLC21A6
  • SLCO1B1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025