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UDP-glucuronosyltransferase 1A4
Summary
- UniProt ID
- P22310
- Gene Symbol
-
- GNT1
- UGT1
- UGT1A4
- Gene ID
- 54657
- Organism
- Homo sapiens (human)
External Links
- GlyConnect
- GlyGen
- P22310
- PubChem
- P22310
- SwissLipids
- The Human Metabolome Database
- HMDBP00478
- Re-Glyco
- P22310
Annotation
- Keyword
-
- Alternative splicing
- Endoplasmic reticulum
- Glycoprotein
- Glycosyltransferase
- Lipid metabolism
- Proteomics identification
- Reference proteome
- Signal
- Transmembrane helix
- Gene Ontology (GO)
| GO Term |
|---|
| endoplasmic reticulum |
| endoplasmic reticulum membrane |
| GO Term |
|---|
| glucuronosyltransferase activity |
| enzyme inhibitor activity |
| enzyme binding |
| protein homodimerization activity |
| protein heterodimerization activity |
Sequence
MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVVLTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNVSLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDLDFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQREVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 119 | N-linked (GlcNAc...) asparagine |
|
||
| 142 | N-linked (GlcNAc...) asparagine |
|
||
| 296 | N-linked (GlcNAc...) asparagine |
|
||
| 348 | N-linked (GlcNAc...) asparagine |
G39188ZX
G14669DU
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Aspirin ADME | Homo sapiens |
| Defective UGT1A4 causes hyperbilirubinemia | Homo sapiens |
| Glucuronidation | Homo sapiens |
| Heme degradation | Homo sapiens |
