Dopamine Neurotransmitter Release Cycle

Summary
Organism
Homo sapiens (human)
Reactome
R-HSA-212676
PubChem
R-HSA-212676
Description
  • Dopamine neurotransmitter cycle occurs in dopaminergic neurons. Dopamine is synthesized and loaded into the clathrin sculpted monoamine transport vesicles. The vesicles are docked, primed and fused with the plasmamembrane in the synapse to release dopamine into the synaptic cleft.
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Displaying entries 1 - 10 of 15 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O14795 Protein unc-13 homolog B
  • UNC13
  • UNC13B
view
O14936 Peripheral plasma membrane protein CASK
  • CASK
  • LIN2
view
O14994 Synapsin-3
  • SYN3
view
O75145 Liprin-alpha-3
  • KIAA0654
  • PPFIA3
view
O75334 Liprin-alpha-2
  • PPFIA2
view
O75335 Liprin-alpha-4
  • KIAA0897
  • PPFIA4
view
P17600 Synapsin-1
  • SYN1
view
P21579 Synaptotagmin-1
  • SVP65
  • SYT
  • SYT1
view
P60880 Synaptosomal-associated protein 25
  • SNAP
  • SNAP25
view
Q02410 Amyloid-beta A4 precursor protein-binding family A member 1
  • APBA1
  • MINT1
  • X11
view

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 6, 2026