Autodegradation of the E3 ubiquitin ligase COP1

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
COP1p-S387-RFWD2ATPADPp-S387-RFWD2:p-S15-TP53p-S15-TP53 Tetramerp-S387-RFWD2ubiquitinated phospho-COP1(ser-387)Ub
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 21 - 25 of 25 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
Q13200 26S proteasome non-ATPase regulatory subunit 2
  • PSMD2
  • TRAP2
view
Q13315 Serine-protein kinase ATM
  • ATM
view
Q16186 Proteasomal ubiquitin receptor ADRM1
  • ADRM1
  • GP110
view
Q8NHY2 E3 ubiquitin-protein ligase COP1
  • COP1
  • RFWD2
  • RNF200
view
Q99460 26S proteasome non-ATPase regulatory subunit 1
  • PSMD1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025