Neurexins and neuroligins

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
NLGN dimersNRXNs:NLGN dimersNRXNsNRXNs:SYTSYTNRXNs:LIN7:CASK:APBA1LIN7:CASK:APBA1STX1A:MUNC18:MINT1,2,(3)NRXNs:STX1A:MUNC18:MINT1,2,(3)NRXNs:LRRTMsLRRTMsNRXNs:NLGN dimers:PSD-95 membersPSD-95 membersNMDA receptor complexNMDA receptor complex:DLG2,DLG3,DLG4GKAP1-4NRXNs:NLGN dimer:PSD-95:GKAP1-4SHANK1,2,3NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3SIPL1SHARPIN:SHANK1,2,3GRM1,GRM5HOMER1,2,3:GRM1,GRM5HOMER1,2,32xHOMER1,2,3:GRM1,GRM5NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:2xHOMER1,2,3:GRM1,5NRXNs:NLGN dimer:PSD-95:GKAP1-4:SHANK1,2,3:DBNLDBNLNMDA receptor complex:PSD-95:BEGAINBEGAINNMDA receptor complex:DLG2,DLG3,DLG4:SPARSPARNMDA receptor complex:DLG2,DLG3,DLG4:SPAR:PDLIM5PDLIM5CASKCASK:Protein 4.1Protein 4.1NRXNs:NLGN dimers:CASK:Protein 4.1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025