RAC1 GTPase cycle

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
GTPGDPRAC1:GTPRAC1:GDPH2OPiRAC1:GDP:RAC1 GDIsARHGDIA,ARHGDIBRAC1:GTP:RAC1 effectorsRAC1 effectorsRAC1:GTPRAC1:GTP:RAC1 endoplasmic reticulum effectorsRAC1 endoplasmic reticulum effectors
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 31 - 40 of 123 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
P50402 Emerin
  • EDMD
  • EMD
  • STA
view
P51149 Ras-related protein Rab-7a
  • RAB7
  • RAB7A
view
P52566 Rho GDP-dissociation inhibitor 2
  • ARHGDIB
  • GDIA2
  • GDID4
  • RAP1GN1
view
P52735 Guanine nucleotide exchange factor VAV2
  • VAV2
view
P60953 Cell division control protein 42 homolog
  • CDC42
view
P63000 Ras-related C3 botulinum toxin substrate 1
  • RAC1
  • TC25
view
P78504 Protein jagged-1
  • JAG1
  • JAGL1
view
P98171 Rho GTPase-activating protein 4
  • ARHGAP4
  • KIAA0131
  • RGC1
  • RHOGAP4
view
Q00587 Cdc42 effector protein 1
  • BORG5
  • CDC42EP1
  • CEP1
  • MSE55
view
Q07889 Son of sevenless homolog 1
  • SOS1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: March 31, 2025