EGR2 and SOX10-mediated initiation of Schwann cell myelination

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
POU3F1 genePOU3F1EGR2 geneEGR2MAG geneMAGMPZ geneMPZPRX genePRX gene:EGR2:SOX10SOX10UTRNL-PRX:DRP2:dystroglycan:laminin-211:UTRNL-PRX dimer:DRP2:Dystroglycan:Laminin-211SCD5 geneSCD5BRG1POU3F1 gene:SOX10 dimer:HDAC2:SMARCA4HDAC2EGR2 gene:POU3F1:POU3F2:SOX10POU3F2ADGRG6ADGRG6-CTF:ADGRG6-NTFADGRG6-CTF:ADGRG6-NTFMAG gene:EGR2:SOX10MBP gene:EGR2:SOX10MBP geneMBPMPZ gene:EGR2:SOX10:SMARCA4PMP22 gene:EGR2:SOX10:TEAD1:WWTR1,YAP1PMP22 GeneTEAD1:WWTR1,YAP1PMP22GJB11 gene:SOX10:EGR2:NAB1,2NAB1,2GJB1 genePRXDRP2L-PRX dimer:DRP2L-PRXMerosinDystroglycanSREBF2 dimerHMGCR gene:EGR2:SREBF2 dimerHMGCR geneHMGCRSCD5 gene:EGR2:SREBF2 dimerCYP51A1 geneCYP51A1 gene:EGR2:SREBF2 dimerCYP51A1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 2 entries
GlyCosmos Lectin UniProt ID Lectin Name Pathway Viewer
GL_000779 P20916 Myelin-associated glycoprotein view
GL_002357 P25189 Myelin protein P0 view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025