Purinergic signaling in leishmaniasis infection

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Interleukin-1 familyInterleukin-1 familyC3AR1C3AR1:C3aC3aATPATPP2RX4,7ATP:P2RX4,7NTPH+H2OPiNDPAMP,GMP,CMP,UMPADP,GDP,CDP,UDPNMNNRNAMATP:P2X4,7 trimerHSP90AB1SUGT1:HSP90SGT1NLRP3NLRP3:SUGT1:HSP90TXNThioredoxin:TXNIPTXNIPROSADFOxidized thioredoxin:TXNIPNLRP3 geneTXNIP:NLRP3NLRP3 elicitor small moleculesNLRP3 elicitor small molecules:NLRP3NLRP3 elicitors:NLRP3 oligomerNLRP3 elicitors:NLRP3 oligomer:ASCASCNLRP3 elicitors:NLRP3 oligomer:ASC:Procaspase-1CASP1Pyrin trimerPSTPIP1 trimer:Pyrin trimerPSTPIP1 trimerPyrin trimer:ASCCASP1CASP1CASP1CASP1Caspase-1 p10/p20 dimerCaspase-1 tetramerInterleukin-1 family propeptidesInterleukin-1 family N-terminal propeptides
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 17 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O15553 Pyrin
  • MEF
  • MEFV
  • TRIM20
view
O43586 Proline-serine-threonine phosphatase-interacting protein 1
  • CD2BP1
  • PSTPIP1
view
O75356 Nucleoside diphosphate phosphatase ENTPD5
  • CD39L4
  • ENTPD5
  • PCPH
view
P01024 Complement C3
  • C3
  • CPAMD1
view
P01583 Interleukin-1 alpha
  • IL1A
  • IL1F1
view
P08238 Heat shock protein HSP 90-beta
  • HSP90AB1
  • HSP90B
  • HSPC2
  • HSPC3
  • HSPCB
view
P08311 Cathepsin G
  • CTSG
view
P19838 Nuclear factor NF-kappa-B p105 subunit
  • NFKB1
view
P21589 5'-nucleotidase
  • NT5
  • NT5E
  • NTE
view
P49961 Ectonucleoside triphosphate diphosphohydrolase 1
  • CD39
  • ENTPD1
view
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025