IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation

Summary
Species
Homo sapiens
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
TRAF6:p-IRAK2p-IRAK2:oligo-TRAF6TRAF6p-IRAK2:K63-linked pUb oligo-TRAF6UbK63polyUbp-IRAK2:K63-linked pUb oligo-TRAF6:free K63 pUb:TAK1 complexTAK1 complexADPATPp-IRAK2:K63-linked pUb oligo-TRAF6:free K63-linked pUb:p-TAK1complex
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024