Downregulation of ERBB4 signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
WWP1/ITCHERBB4/m80/s80:WWP1/ITCHERBB4/ERBB4m80/ERBB4s80UbUb-ERBB4:WWP1/ITCHNedd4ERBB4jmAcyt1s80:NEDD4ERBB4jmAcyt1s80 dimerUb-ERBB4jmAcyt1s80:NEDD4E4ICDERBB4s80:MyrG-p-Y419-SRCP05480
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying all 4 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P05480 Proto-oncogene tyrosine-protein kinase Src
  • Src
view
P0CG49 Polyubiquitin-B
  • Ubb
view
P46935 E3 ubiquitin-protein ligase NEDD4
  • Kiaa0093
  • Nedd-4
  • Nedd4
  • Nedd4-1
  • Nedd4a
  • Rpf1
view
Q61527 Receptor tyrosine-protein kinase erbB-4
  • Erbb4
  • Mer4
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025