Sema3A PAK dependent Axon repulsion

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
HSP90AA1,HSP90AB1pLIMK dimer:HSP-90P53668ATPActive LIMK1ADPSema3A:Nrp-1:pPlexinA:Fyn:Fes:Rac-1-GTPPAK1,2,3Sema3A:Nrp-1:PlexinA:Rac1-GTP:PAKPAK1,2,3 dimerSema3A:Nrp-1:PlexinA:Rac1-GTP:pPAKLIMK1
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
Displaying entries 1 - 10 of 13 in total
UniProt ID Protein Name Gene Symbol Pathway Viewer
O08665 Semaphorin-3A
  • SemD
  • Sema3a
  • Semad
view
O88643 Serine/threonine-protein kinase PAK 1
  • Pak1
  • Paka
view
P07901 Heat shock protein HSP 90-alpha
  • Hsp86
  • Hsp86-1
  • Hsp90aa1
  • Hspca
view
P11499 Heat shock protein HSP 90-beta
  • Hsp84
  • Hsp84-1
  • Hsp90ab1
  • Hspc3
  • Hspcb
view
P16879 Tyrosine-protein kinase Fes/Fps
  • Fes
  • Fps
view
P53668 LIM domain kinase 1
  • Limk
  • Limk1
view
P70206 Plexin-A1
  • Kiaa4053
  • Plxna1
view
P70207 Plexin-A2
  • Kiaa0463
  • Plxna2
view
P70208 Plexin-A3
  • Plxna3
view
P97333 Neuropilin-1
  • Nrp
  • Nrp1
view
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025