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MIRAGE
Interleukin-10 signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Il10IL10 dimerIL10 dimer:2xIL10RA:JAK1IL10RA:JAK1IL10RB:TYK2IL10 dimer:2xIL10RA:JAK1:2xIL10RB:TYK2ATPIL10 dimer:2xIL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2ADPIL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:STAT3Stat3IL10 dimer:2xp-Y-IL10RA:p-Y-JAK1:2xIL10RB:p-Y-TYK2:p-Y705-STAT3P42227p-Y705-STAT3 dimerp-Y705-STAT3 dimer
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
SPV: a JavaScript Signaling Pathway Visualizer, Bioinformatics, 2018
Displaying all 5 entries
UniProt ID Protein Name Gene Symbol Pathway Viewer
P18893 Interleukin-10
  • Il-10
  • Il10
 view
P42227 Signal transducer and activator of transcription 3
  • Aprf
  • Stat3
 view
P52332 Tyrosine-protein kinase JAK1
  • Jak1
 view
Q61190 Interleukin-10 receptor subunit beta
  • Crfb4
  • Il10rb
 view
Q61727 Interleukin-10 receptor subunit alpha
  • Il10r
  • Il10ra
 view
If you want to check the location of a particular molecule, you can do so by clicking on the "Switching Highlight" button on the page you have navigated to by clicking on "view".
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: February 17, 2025