Interleukin-2 signaling

Summary
Species
Mus musculus
Reactome
PubChem
Click on a node on the pathway to see its details. Glycoproteins are marked with a glycoprotein icon in their name.
Il2raIL2:IL2RAIl2Il2rbIL2RB:JAK1JAK1IL2:IL2RA:IL2RB:JAK1JAK3IL2RG:JAK3Il2rgJAK3:JAK3 inhibitorsJAK3 inhibitorsIL2:IL2R trimer:JAK1:JAK3IL2:IL2R trimer:p-JAK1:JAK3ADPATPIL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:SHCShc1IL2:IL2R trimer p-(Y338,392,510) beta subunit:p-JAK1:JAK3:STAT5STAT5IL2:IL2R trimer p-(Y338,392,510)-beta subunit:p-JAK1:JAK3:p-SHCIL2:IL2R trimer p-(Y338,Y392, Y510) beta subunit:p-JAK1:JAK3:p-STAT5p-STAT5IL2:IL2R trimer:p-JAK1:JAK3:SYKSYKIL2:IL2R trimer:p-JAK1:JAK3:p-SYKPTK2BJAK3:PYK2JAK3:p-PYK2
ProteinProtein familyDNARNAComplexChemical/MoleculePhenotype/StimulusNucleusMitochondriaEndosomeGolgi apparatusLysosomeMembraneUp-regulatesDown-regulatesPhysical interactionUnknownDirectIndirectBindingHighlight
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: February 17, 2025