GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **376 - 400** of **499** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	60S ribosomal protein L29 Eukaryotic peptide chain release factor GTP-binding subunit Eukaryotic peptide chain release factor subunit 1 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23B Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5B Large ribosomal subunit protein uL6 MIF4G domain-containing protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Plectin/S10 N-terminal domain-containing protein Polyadenylate-binding protein Regulator of nonsense transcripts 1 Ribosomal Protein, Small subunit Ribosomal protein L37 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS9 Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein	A0A486WX07 G4S0D4 O01504 O01692 O01763 O01802 O01868 O01869 O02056 O02639 O16520 O17218 O17570 O18240 O18650 O44480 O45226 O45499 O45622 O45946 O62388 O76512 P34334 P34662 P37165 P46769 P47991 P48150 P48152 P48154 P48156 P48158 P48166 P49041 P49180 P49181 P49196 P49197 P49405 P50880 P51403 P51404 P52814 P52819 P52821 P61866 P90983 P91053 P91055 P91128 P91374 P91913 P91914 Q09533 Q19162 Q19869 Q19877 Q1XFY9 Q20206 Q20228 Q20647 Q21930 Q22054 Q22716 Q23312 Q27389 Q8WQA8 Q93572 Q93594 Q95Y04 Q95Y90 Q966C6 Q9BKU5 Q9BL19 Q9N3X2 Q9N4I4 Q9NEN6 Q9TXP0 Q9U2A8 Q9U302 Q9U332 Q9XVE9 Q9XVF7 Q9XVP0 Q9XWS4	C16C8.14 C16C8.16 C16C8.20 C37A2.7 CELE_W01D2.1 CELE_Y37E3.8 cbp-20 cbp-80 erfa-1 erfa-3 etf-1 ifg-1 ncbp-1 ncbp-2 pab-1 rla-0 rla-1 rpa-0 rpa-1 rpl-1 rpl-10 rpl-10a rpl-11.2 rpl-12 rpl-13 rpl-14 rpl-15 rpl-16 rpl-17 rpl-18 rpl-19 rpl-2 rpl-20 rpl-21 rpl-22 rpl-23 rpl-24.1 rpl-25.2 rpl-26 rpl-27 rpl-28 rpl-29 rpl-3 rpl-30 rpl-31 rpl-32 rpl-33 rpl-35 rpl-36 rpl-36.A rpl-37a rpl-38 rpl-39 rpl-4 rpl-41 rpl-43 rpl-5 rpl-6 rpl-7 rpl-7A rpl-8 rpl-9 rps-0 rps-1 rps-10 rps-11 rps-12 rps-13 rps-14 rps-15 rps-16 rps-17 rps-18 rps-19 rps-2 rps-20 rps-21 rps-22 rps-23 rps-24 rps-25 rps-26 rps-27 rps-28 rps-29 rps-3 rps-4 rps-5 rps-6 rps-7 rps-8 rps-9 smg-2 ubl-1	Caenorhabditis elegans
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	60S ribosomal protein L29 Eukaryotic peptide chain release factor GTP-binding subunit Eukaryotic peptide chain release factor subunit 1 Large ribosomal subunit protein P1 Large ribosomal subunit protein P2 Large ribosomal subunit protein eL13 Large ribosomal subunit protein eL14 Large ribosomal subunit protein eL15 Large ribosomal subunit protein eL18 Large ribosomal subunit protein eL19 Large ribosomal subunit protein eL20 Large ribosomal subunit protein eL21 Large ribosomal subunit protein eL22 Large ribosomal subunit protein eL24 Large ribosomal subunit protein eL27 Large ribosomal subunit protein eL28 Large ribosomal subunit protein eL30 Large ribosomal subunit protein eL31 Large ribosomal subunit protein eL32 Large ribosomal subunit protein eL33 Large ribosomal subunit protein eL36 Large ribosomal subunit protein eL38 Large ribosomal subunit protein eL39 Large ribosomal subunit protein eL42 Large ribosomal subunit protein eL43 Large ribosomal subunit protein eL6 Large ribosomal subunit protein eL8 Large ribosomal subunit protein uL10 Large ribosomal subunit protein uL11 Large ribosomal subunit protein uL13 Large ribosomal subunit protein uL14 Large ribosomal subunit protein uL15 Large ribosomal subunit protein uL16 Large ribosomal subunit protein uL18 Large ribosomal subunit protein uL1 Large ribosomal subunit protein uL22 Large ribosomal subunit protein uL23B Large ribosomal subunit protein uL24 Large ribosomal subunit protein uL29 Large ribosomal subunit protein uL2 Large ribosomal subunit protein uL30 Large ribosomal subunit protein uL3 Large ribosomal subunit protein uL4 Large ribosomal subunit protein uL5B Large ribosomal subunit protein uL6 MIF4G domain-containing protein MIF4G domain-containing protein Nonsense-mediated mRNA decay factor SMG8 Nonsense-mediated mRNA decay factor SMG9 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PIN domain-containing protein Plectin/S10 N-terminal domain-containing protein Polyadenylate-binding protein Probable serine/threonine-protein phosphatase PP2A regulatory subunit Protein CASC3 Protein mago nashi homolog RNA helicase RNA-binding protein rnp-4 RRM domain-containing protein Regulator of nonsense transcripts 1 Ribosomal Protein, Small subunit Ribosomal protein L37 Serine/threonine-protein kinase smg-1 Serine/threonine-protein phosphatase 2A catalytic subunit Serine/threonine-protein phosphatase 2A regulatory subunit sur-6 Small ribosomal subunit protein eS12 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS9 UPF3 domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like domain-containing protein Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein	A0A486WX07 C2BR97 G4S0D4 G5EDE4 G5EDR3 G5EGK8 O01504 O01510 O01692 O01763 O01802 O01868 O01869 O02056 O02639 O16520 O17218 O17570 O18240 O18650 O44480 O45226 O45499 O45622 O45946 O62301 O62388 O76512 P34334 P34662 P37165 P46769 P47991 P48150 P48152 P48154 P48156 P48158 P48166 P49029 P49041 P49180 P49181 P49196 P49197 P49405 P50880 P51403 P51404 P52814 P52819 P52821 P61866 P90983 P91053 P91055 P91128 P91374 P91913 P91914 Q09533 Q09543 Q19162 Q19869 Q19877 Q1XFY9 Q20206 Q20228 Q20647 Q21155 Q21832 Q21930 Q22054 Q22716 Q23312 Q27389 Q8WQA8 Q8WQF3 Q93572 Q93594 Q95Y04 Q95Y90 Q966C6 Q9BKU5 Q9BL19 Q9BL61 Q9BL68 Q9N3X2 Q9N4I4 Q9NEN6 Q9TXP0 Q9U2A8 Q9U302 Q9U332 Q9XVE9 Q9XVF7 Q9XVP0 Q9XWJ1 Q9XWS4	C16C8.14 C16C8.16 C16C8.20 C37A2.7 CELE_W01D2.1 CELE_Y37E3.8 RBM8 Y14 casc-3 cbp-20 cbp-80 eif-4A3 erfa-1 erfa-3 etf-1 ifg-1 let-92 mag-1 ncbp-1 ncbp-2 paa-1 pab-1 rla-0 rla-1 rnp-4 rnp-5 rpa-0 rpa-1 rpl-1 rpl-10 rpl-10a rpl-11.2 rpl-12 rpl-13 rpl-14 rpl-15 rpl-16 rpl-17 rpl-18 rpl-19 rpl-2 rpl-20 rpl-21 rpl-22 rpl-23 rpl-24.1 rpl-25.2 rpl-26 rpl-27 rpl-28 rpl-29 rpl-3 rpl-30 rpl-31 rpl-32 rpl-33 rpl-35 rpl-36 rpl-36.A rpl-37a rpl-38 rpl-39 rpl-4 rpl-41 rpl-43 rpl-5 rpl-6 rpl-7 rpl-7A rpl-8 rpl-9 rps-0 rps-1 rps-10 rps-11 rps-12 rps-13 rps-14 rps-15 rps-16 rps-17 rps-18 rps-19 rps-2 rps-20 rps-21 rps-22 rps-23 rps-24 rps-25 rps-26 rps-27 rps-28 rps-29 rps-3 rps-4 rps-5 rps-6 rps-7 rps-8 rps-9 smg-1 smg-2 smg-3 smg-4 smg-6 smg-8 smg-9 sur-6 ubl-1	Caenorhabditis elegans
Sphingolipid catabolism	Aldehyde dehydrogenase Aldehyde dehydrogenase Alkaline ceramidase Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Phospholipid phosphatase homolog 1.2 homolog Sphingosine-1-phosphate lyase	A0A486WWU7 H2KZD1 O44555 O45145 Q10022 Q19403 Q9Y194	W02F12.2 alh-4 alh-5 plpp-1.1 plpp-1.2 plpp-1.3 spl-1	Caenorhabditis elegans
Peroxisomal protein import	2-hydroxyacyl-CoA lyase Acyl-coenzyme A oxidase acox-1.1 Acyl-coenzyme A oxidase acox-1.2 Acyl-coenzyme A oxidase acox-1.3 Acyl-coenzyme A oxidase acox-1.4 Acyl-coenzyme A oxidase acox-3 Acyl-coenzyme A oxidase Acyl-coenzyme A thioesterase 1-like Alanine--glyoxylate aminotransferase Alpha-methylacyl-CoA racemase Amine oxidase domain-containing protein BAAT/acyl-CoA thioester hydrolase protein BAAT/acyl-CoA thioester hydrolase protein BAAT_C domain-containing protein Catalase Choline/carnitine acyltransferase domain-containing protein Choline/carnitine acyltransferase domain-containing protein D-amino-acid oxidase D-aspartate oxidase 1 D-aspartate oxidase 2 D-aspartate oxidase 3 Dehydrogenase/reductase SDR family member 4 Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial Dihydroxyacetone phosphate acyltransferase Enoyl-CoA Hydratase FMN hydroxy acid dehydrogenase domain-containing protein Glutathione s-transferase kappa 2 Insulin-degrading enzyme Isocitrate dehydrogenase [NADP] Lon protease homolog 2, peroxisomal Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Malonyl-CoA decarboxylase, mitochondrial MaoC-like domain-containing protein Mpv17-like protein Peroxisomal coenzyme A diphosphatase ndx-8 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisome assembly protein 12 Polyubiquitin-A Probable acyl-coenzyme A oxidase acox-1.5 Putative nudix hydrolase 7 Putative sarcosine oxidase RING-type E3 ubiquitin transferase TPR_REGION domain-containing protein UBA domain-containing protein Ubiquitin-conjugating enzyme E2 2 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized protein B0272.4 hydroxymethylglutaryl-CoA lyase palmitoyl-CoA hydrolase	A0A486WVT5 B1GRK5 B3WFZ3 G5EFP8 G5EG81 G5EGA6 H9G2T4 O01739 O01862 O16249 O17761 O45003 O45307 O62137 O62138 O62139 O62140 O76383 P0CG71 P34355 P35129 P37165 P41942 P49632 P91148 Q17474 Q17499 Q18006 Q18122 Q18355 Q18426 Q18916 Q18973 Q19058 Q19189 Q19564 Q19878 Q19951 Q20048 Q20959 Q20992 Q7YWV6 Q8MYL7 Q93839 Q93930 Q94055 Q95XG9 Q95XN1 Q9BIA9 Q9GYN3 Q9NA25 Q9XW87	B0272.4 B0395.3 C15B12.1 C17C3.1 C24A3.4 C31H5.6 C32D5.11 CELE_F41E6.5 CELE_F44E7.4 CELE_F58A6.1 CELE_K05B2.4 CELE_T05E7.1 CELE_T20B3.1 CELE_T24B8.7 CELE_W03D8.8 CELE_Y71G12B.10 T18D3.9 acl-7 acox-1 acox-1.1 acox-1.2 acox-1.3 acox-1.4 acox-1.5 acox-1.6 acox-2 acox-3 acox-4 acox-5 acox-6 acs-20 acs-22 agxt-1 ctl-3 daao-1 dapat ddo-1 ddo-2 ddo-3 dhrs-4 ech-8 gstk-2 hacl-1 hpo-15 idh-1 let-70 lonp-2 maoc-1 mlcd-1 ndx-7 ndx-8 prx-12 prx-13 prx-14 prx-5 ubc-2 ubia ubib ubl-1 ubq-1 ubq-2	Caenorhabditis elegans
Synthesis of Leukotrienes (LT) and Eoxins (EX)	Aminopeptidase ltah-1.1 Gamma-glutamyltransferase Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Multidrug resistance-associated protein 1	A0A486WVP7 B5BM47 G5EFT4 H2L030 H2L0B7 O18256 Q3S1M2 Q9N5V4	C53D5.5 CELE_H14N18.4 CELE_T03D8.6 CELE_T19H12.6 CELE_Y7A9A.1 CELE_Y97E10AR.2 ltah-1.1 mrp-1	Caenorhabditis elegans
Glutathione synthesis and recycling	5-oxoprolinase GCS light chain Gamma-glutamylcyclotransferase Gamma-glutamyltransferase Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Gamma-glutamyltranspeptidase 1 Glutamate--cysteine ligase Glutathione synthetase Peptidase M20 dimerisation domain-containing protein gamma-glutamylcyclotransferase	A0A486WVP7 A0A9S2 A9CZN9 B5BM47 H2L030 H2L0B7 O18000 O18256 Q18596 Q20117 Q21549 Q9GZE8 Q9N5V4	C44B7.7 C53D5.5 CELE_E01A2.1 CELE_F22F7.7 CELE_H14N18.4 CELE_T03D8.6 CELE_T19H12.6 CELE_Y38F2AR.12 CELE_Y7A9A.1 CELE_Y97E10AR.2 gcs-1 gss-1 pes-9	Caenorhabditis elegans
RHO GTPases Activate WASPs and WAVEs	Actin-1 Actin-2 Actin-3 Actin-4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog Inactive tyrosine-protein kinase kin-32 Membrane-associated protein gex-3 Mitogen-activated protein kinase mpk-1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Probable actin-related protein 2/3 complex subunit 2 Probable actin-related protein 2/3 complex subunit 3 Probable actin-related protein 2/3 complex subunit 4 Protein BRICK1 Ras-related protein ced-10 SH3 domain-containing protein SPIN90/Ldb17 leucine-rich domain-containing protein Sex muscle abnormal protein 5 Tyrosine-protein kinase abl-1 WASH complex subunit homolog 1 Wiskott-Aldrich syndrome protein family member	A0A3P6PCS5 A5Z2X2 O18195 O44518 O61861 P03949 P0DM41 P0DM42 P10984 P10986 P29355 P39745 P53489 P55163 P58798 Q03206 Q05062 Q10929 Q8WTM6 Q95PX0 Q95YD4 Q9N372 Q9N4I0 Q9XVK6 Q9XWV3	CELE_Y55F3AM.5 CELE_Y57G11C.1147 abi-1 abl-1 act-1 act-2 act-3 act-4 arp-2 arx-1 arx-2 arx-3 arx-4 arx-5 arx-6 arx-7 cdc-42 ced-10 ddl-2 gex-2 gex-3 kin-32 mpk-1 nck-1 rac-1 sem-5 sur-1 wve-1	Caenorhabditis elegans
Regulation of actin dynamics for phagocytic cup formation	Actin-1 Actin-2 Actin-3 Actin-4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Cell division control protein 42 homolog Cytoplasmic FMR1-interacting protein homolog FERM domain-containing protein Inactive tyrosine-protein kinase kin-32 Membrane-associated protein gex-3 Mitogen-activated protein kinase mpk-1 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Probable actin-related protein 2/3 complex subunit 2 Probable actin-related protein 2/3 complex subunit 3 Probable actin-related protein 2/3 complex subunit 4 Protein BRICK1 Ras-related protein ced-10 SH3 domain-containing protein SPIN90/Ldb17 leucine-rich domain-containing protein Serine/threonine-protein kinase pak-1 Sex muscle abnormal protein 5 Tyrosine-protein kinase abl-1 WASH complex subunit homolog 1 Wiskott-Aldrich syndrome protein family member	A0A3P6PCS5 A5Z2X2 H2KYX3 O18195 O44518 O61861 P03949 P0DM41 P0DM42 P10984 P10986 P29355 P39745 P53489 P55163 P58798 Q03206 Q05062 Q10929 Q17850 Q8WTM6 Q95PX0 Q95YD4 Q9N372 Q9N4I0 Q9XVK6 Q9XWV3	CELE_Y55F3AM.5 CELE_Y57G11C.1147 abi-1 abl-1 act-1 act-2 act-3 act-4 arp-2 arx-1 arx-2 arx-3 arx-4 arx-5 arx-6 arx-7 cdc-42 ced-10 ddl-2 gex-2 gex-3 kin-32 mpk-1 nck-1 nfm-1 pak-1 rac-1 sem-5 sur-1 wve-1	Caenorhabditis elegans
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor (51.1 kD) (Acr-22) Acetylcholine receptor subunit alpha-type acr-5 Acetylcholine receptor subunit alpha-type deg-3 Acetylcholine receptor subunit alpha-type des-2 Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Betaine receptor acr-23 Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-gated ion channel 4 Neur_chan_LBD domain-containing protein Neur_chan_memb domain-containing protein Neurotransmitter-gated ion-channel ligand binding domain protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Proton-gated ion channel subunit pbo-6	A0A3P6P985 B1Q281 G5EDF1 G5EE87 G5EG88 G5EGR1 H2KML8 O18228 O44452 O61216 O61519 O61520 O76554 P48181 P48182 P54244 P54245 P54246 Q19351 Q23022 Q23355 Q27218 Q65XS8 Q6BEQ0 Q93149 Q93329 Q95Y94 Q9N4M3 Q9N587 V6CJ96	acr-12 acr-2 acr-20 acr-21 acr-22 acr-23 acr-24 acr-25 acr-3 acr-4 acr-5 acr-6 acr-8 deg-3 des-2 lev-1 lev-7 lev-8 lgc-10 lgc-11 lgc-12 lgc-3 lgc-30 lgc-31 lgc-4 lgc-5 lgc-6 lgc-7 lgc-8 lgc-9 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
GABA receptor activation	Gamma-aminobutyric acid receptor exp-1 Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Ligand-Gated ion Channel Ligand-Gated ion Channel Neurotransmitter-gated ion-channel ligand-binding domain-containing protein	A0A3P6NNS2 G5ECD3 G5ECJ0 G5ECN1 O18276 Q6BET0 Q7YTP9 Q9U2E2	exp-1 gab-1 lgc-35 lgc-36 lgc-37 lgc-38 lgc-43 unc-49 unc-49B	Caenorhabditis elegans
pre-mRNA splicing	ATP-dependent RNA helicase B30.2/SPRY domain-containing protein Beta-catenin-like protein 1 N-terminal domain-containing protein CBF1-interacting co-repressor CIR N-terminal domain-containing protein CID domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein Cell division cycle 5-like protein Chromatin target of PRMT1 protein C-terminal domain-containing protein Coiled-coil domain-containing protein 12 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 G patch domain-containing protein 1 homolog Gastrulation defective protein 1 General transcription factor IIF subunit 2 Heat shock protein hsp-1 Hepatocellular carcinoma-associated antigen 59 Heterogeneous nuclear ribonucleoprotein A1 Heterogeneous nuclear ribonucleoprotein K homolog Intron-binding protein aquarius K Homology domain-containing protein NF-kappa-B-activating protein C-terminal domain-containing protein Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 Nuclear speckle splicing regulatory protein 1 homolog PHD finger-like domain-containing protein 5A PPIase cyclophilin-type domain-containing protein PWI domain-containing protein Peptidyl-prolyl cis-trans isomerase 10 Peptidyl-prolyl cis-trans isomerase 4 Peptidyl-prolyl cis-trans isomerase sig-7 Peptidyl-prolyl cis-trans isomerase Pinin/SDK/MemA protein domain-containing protein Poly(U)-binding-splicing factor rnp-6 Pre-mRNA-processing factor 19 Pre-mRNA-splicing factor 18 Pre-mRNA-splicing factor 8 homolog Pre-mRNA-splicing factor ATP-dependent RNA helicase ddx-15 Pre-mRNA-splicing factor CWC22 homolog Pre-mRNA-splicing factor CWC25 homolog Pre-mRNA-splicing factor RBM22 Pre-mRNA-splicing factor SLU7 Pre-mRNA-splicing factor SPF27 Pre-mRNA-splicing factor SYF1 Pre-mRNA-splicing factor syf-2 Probable ATP-dependent RNA helicase DHX35 homolog Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable U2 small nuclear ribonucleoprotein A' Probable histone deacetylase complex subunit SAP18 Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-1 Probable pre-mRNA-splicing factor ATP-dependent RNA helicase mog-5 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein Sm D1 Probable small nuclear ribonucleoprotein Sm D2 Probable small nuclear ribonucleoprotein-associated protein B Probable splicing factor, arginine/serine-rich 2 Probable splicing factor, arginine/serine-rich 3 Probable splicing factor, arginine/serine-rich 4 Probable splicing factor, arginine/serine-rich 6 Probable splicing factor, arginine/serine-rich 7 Proline-rich protein PRCC Protein BUD31 homolog Protein CASC3 Protein FAM32A Protein FAM50 homolog Protein isy-1 Protein mago nashi homolog Putative RNA-binding protein PTB-1a Putative RNA-binding protein R05D3.8 RNA helicase RNA helicase RNA helicase RNA polymerase Rpb4/RPC9 core domain-containing protein RNA-binding protein 5 RNA-binding protein FUS RNA-binding protein rnp-4 RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein RRM domain-containing protein Replication stress response regulator SDE2 SAP domain-containing protein STING ER exit protein Schlafen-like protein 2 Serrate RNA effector molecule homolog Small nuclear ribonucleoprotein Sm D3 Spliceosome RNA helicase DDX39B homolog Spliceosome-associated protein CWC15 homolog Splicing factor 45 Splicing factor Cactin Splicing factor YJU2 TPR_REGION domain-containing protein Tr-type G domain-containing protein Transcription initiation factor IIF subunit alpha U2 snRNP-associated SURP motif-containing protein U5 small nuclear ribonucleoprotein 200 kDa helicase UPF3 domain-containing protein Uncharacterized protein F37A4.2 Uncharacterized protein T27F2.1 WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein WW domain-containing protein Zinc finger protein 830 mRNA transport homolog 4	A0A3P6MY32 A9D4S6 B9WRU1 D0G911 G5EBT5 G5EBY6 G5EC45 G5ED97 G5EDE4 G5EDH3 G5EDV3 G5EEL2 G5EEW6 G5EFC4 G5EG14 O01159 O01763 O02092 O02097 O16519 O16786 O18219 O44729 O45431 O45766 O62185 O62213 P09446 P16356 P34313 P34369 P34498 P34541 P34659 P41880 P49029 P52012 P52017 P91156 P91175 P91277 P91306 P91398 P91401 P91918 Q09250 Q09252 Q09385 Q09511 Q09530 Q10013 Q10051 Q10578 Q17336 Q17348 Q17558 Q17684 Q18212 Q18265 Q18409 Q18445 Q18535 Q18691 Q18786 Q18999 Q19211 Q19614 Q19826 Q20124 Q20716 Q20875 Q20966 Q21155 Q21278 Q21322 Q21559 Q21827 Q21832 Q22037 Q22139 Q22412 Q22417 Q22836 Q23120 Q23223 Q23463 Q4W5P0 Q8MXR2 Q8MYM8 Q8WQF3 Q93338 Q93594 Q95Q06 Q95QR5 Q95XJ1 Q95Y67 Q95YF1 Q95ZQ5 Q965K2 Q965S0 Q966L5 Q966L6 Q9BIB7 Q9BIC2 Q9BKQ8 Q9BL61 Q9BLB6 Q9GR61 Q9N3C9 Q9N3S4 Q9N4G9 Q9N5K1 Q9N5K2 Q9NEW6 Q9NLD1 Q9U1Q3 Q9U1Q7 Q9U2G0 Q9U3I0 Q9XTU6 Q9XTZ2 Q9XUW5 Q9XVH6 Q9XVH9	C16C10.4 C47E8.4 CELE_K01G5.8 CELE_T23G11.4 CELE_Y18H1A.2 CELE_Y57G11A.5 CELE_Y66D12A.8 CELE_ZK616.1 E01A2.2 F37A4.2 K07C5.6 R05D3.8 R07E5.1 RBM8 T27F2.1 Y14 acin-1 aly-3 ama-1 bcas-2 bud-31 cacn-1 casc-3 cbp-20 cbp-80 ccdc-12 ccdc-55 cdc-5L cdc-5l cey-1 cey-2 cey-3 cey-4 ctnb-1 cwc-15 cyn-10 cyn-12 cyn-15 cyn-4 cyp-10 cyp-4 ddx-15 ddx-17 ddx-35 ddx-46 eftu-2 eif-4A3 emb-4 fust-1 gad-1 gtf-2F1 gtf-2F2 gtf-2f1 gtf-2f2 hel-1 hrp-1 hrp-2 hrpf-1 hrpf-2 hrpk-1 hrpl-1 hrpr-1 hrpu-1 hsp-1 hsp70a isy-1 let-504 let-858 mag-1 mog-1 mog-2 mog-3 mog-5 mog-6 mtr-4 ncbp-1 ncbp-2 pes-4 phf-5 plrg-1 pnn-1 pqbp-1.1 prcc-1 prp-17 prp-18 prp-19 prp-8 ptb-1 rbm-17 rbm-22 rbm-5 rbp-1 rnp-2 rnp-4 rnp-5 rnp-6 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 rsp-2 rsp-3 rsp-4 rsp-6 rsp-7 rsp-8 rsr-1 sacy-1 sap-1 sap-140 scaf-6 sde-2 sel-13 sig-7 smg-4 snr-1 snr-2 snr-3 snr-4 snr-5 snr-6 snr-7 snrp-200 snrp-40.1 snrp-40.2 sqd-1 srp-1 srp-2 srp-4 syf-1 syf-2 syf-3 tag-65 tofu-2 yju-2	Caenorhabditis elegans
Sphingolipid de novo biosynthesis	3-dehydrosphinganine reductase ABC transporter domain-containing protein ABC transporter family G domain-containing protein BED-type domain-containing protein Casein kinase I gamma Ceramide synthase hyl-1 Ceramide synthase hyl-2 Cytochrome b5 heme-binding domain-containing protein Cytochrome b5 heme-binding domain-containing protein Fatty acid 2-hydroxylase Glycolipid transfer protein domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Multidrug resistance-associated protein 1 Oxysterol-binding protein Phosphatidylcholine Phosphatidylcholine Probable ceramide synthase lagr-1 Putative phosphatidylcholine Putative sphingolipid delta(4)-desaturase/C4-monooxygenase Putative sphingolipid delta(4)-desaturase Serine/threonine-protein kinase dkf-1 Serine/threonine-protein kinase dkf-2 Sphingomyelin synthase-related 1 Sphingomyelin synthase-related 2 Sphingosine kinase 1	A0A3B1DV80 A0A5K1IBA7 A7DTF2 D7SFK1 G5EC63 G5ED45 O01927 O44186 O45818 Q18425 Q18545 Q19235 Q19585 Q20696 Q20735 Q20976 Q3S1M2 Q7Z139 Q8WQ99 Q93315 Q965Q4 Q9BKS2 Q9TYV2 Q9U3D4 Q9XUJ7 Q9XVS0 Q9XWE9 U4PBL3	CELE_F58B4.2 CELE_Y37E11AM.3 CELE_Y82E9BR.14 F33D4.4 F53B1.2 abcx-1 bed-2 csnk-1 cytb-5.1 dkf-1 dkf-2 fath-1 hyl-1 hyl-2 lagr-1 mrp-1 obr-1 sms-1 sms-2 sms-3 sms-5 sphk-1 spin-1 spin-2 spin-3 spin-4 tag-274 ttm-5 wht-5	Caenorhabditis elegans
RHOD GTPase cycle	Adducin-related protein 1 Adducin-related protein 2 Alpha-actinin, sarcomeric Anion exchange protein C2 domain-containing protein Caveolin-1 Caveolin-2 Cortactin-binding protein-2 N-terminal domain-containing protein EF-hand domain-containing protein ERGIC-53-like protein F-actin-capping protein subunit beta FH2 domain-containing protein GEX Interacting protein GTPase-activating protein pac-1 Golgin subfamily A conserved domain-containing protein Intermediate filament protein ifa-1 Intermediate filament protein ifa-2 Intermediate filament protein ifa-3 Intermediate filament protein ifa-4 Intermediate filament protein ifb-1 Intermediate filament protein ifb-2 Intermediate filament protein ifc-1 Intermediate filament protein ifc-2 Intermediate filament protein ifd-1 Intermediate filament protein ifd-2 Intermediate filament protein ifp-1 Lamin-1 Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Major sperm protein Nicotinic receptor-associated protein 1 Phosphoinositide 3-kinase adapter subunit Plexin-2 Protein let-99 Protein vem-1 Rac GTPase-activating protein 1 Ras-like GTP-binding protein rhoA Ras-related protein Rab-7a Rho GTPase-activating protein 26 Rho GTPase-activating protein 68F Rho-GAP domain-containing protein Rho-GAP domain-containing protein Sema domain-containing protein Serine/threonine-protein kinase VRK1 Serine/threonine-protein kinase pak-2 Synaptobrevin-1 Target of ERK kinase mpk-1 Torsin-1B Vang-like protein WAPL domain-containing protein WW domain-containing protein tag-325	A0A2K5AU23 A0A679L8R0 B3WFV9 G5EDE8 G5EDP9 G5EFU0 H2KY90 H2KZH5 H2KZV6 O01630 O02163 O02365 O02495 O17099 O44782 O45168 O45611 O45657 P34288 P34686 P46941 P90900 P90901 P91330 Q09501 Q10956 Q17955 Q18879 Q19286 Q19289 Q19479 Q19782 Q19848 Q19989 Q20952 Q20981 Q21065 Q21067 Q21341 Q21443 Q22038 Q22622 Q23130 Q23146 Q23158 Q7JP75 Q7K7J0 Q7YZW5 Q86DC6 Q94051 Q95QQ9 Q95XR9 Q9U2A6 Q9U9K0 Q9XUB9 Q9XUS9 U4PRY7	C14A4.8 C49H3.6 CELE_F42G2.5 CELE_F54H5.3 CELE_F58E6.5 CELE_T04C9.1 CELE_T09B4.2 CELE_Y38F2AR.10 CELE_ZC196.2 aap-1 abts-1 add-1 add-2 atn-1 cap-2 cav-1 cav-2 cyk-1 cyk-4 efhd-1 esyt-2 gap gei-18 golg-2 hpo-28 ifa-1 ifa-2 ifa-3 ifa-4 ifb-1 ifb-2 ifc-1 ifc-2 ifd-1 ifd-2 ifp-1 ile-1 inft-2 lam-1 let-99 lmn-1 mua-6 nra-1 osm-10 pac-1 pak-2 plx-1 plx-2 rab-7 rga-1 rga-5 rga-8 rho-1 rhoa snb-1 tag-325 toe-2 vang-1 vem-1 vpr-1 vrk-1	Caenorhabditis elegans
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Aldehyde dehydrogenase Aldehyde dehydrogenase Amyloid-beta-like protein Cytochrome b5 heme-binding domain-containing protein E2 ubiquitin-conjugating enzyme Major sperm protein Protein transport protein Sec61 subunit beta Protein transport protein Sec61 subunit gamma Putative syntaxin-5 SGTA homodimerisation domain-containing protein Stress-associated endoplasmic reticulum protein 2 Synaptobrevin-1 Synaptobrevin-like protein 5 Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein	A0A2K5ATR7 A0A486WWU7 G5EBK2 O02495 O16000 O44555 O44782 P34351 Q10651 Q19767 Q19967 Q20797 Q21746 Q93315 Q93838 Q94057 Q95XH1 Q95XS2	alh-4 alh-5 apl-1 cytb-5.1 emo-1 oar-1 sec-61.B sec-61.G sec-61.b serp-1.1 sgt-1 snb-1 snb-2 snb-5 snb-6 snb-7 syn-3 syx-5 ubc-26 unc-64 vamp-7 vpr-1	Caenorhabditis elegans
RET signaling	GDNF/GAS1 domain-containing protein Protein kinase domain-containing protein	A0A2C9C3B4 Q95XG5	CELE_F09G2.1 CELE_Y69A2AR.31	Caenorhabditis elegans
RAB geranylgeranylation	GTP-binding protein Rhes Geranylgeranyl transferase type-2 subunit alpha Probable geranylgeranyl transferase type-2 subunit beta RAB family RAB family RAB family RAB family Rab proteins geranylgeranyltransferase component A 1 Rab27 Rab8 Ras and EF-hand domain-containing protein homolog Ras-related protein Rab-10 Ras-related protein Rab-10 Ras-related protein Rab-14 Ras-related protein Rab-18 Ras-related protein Rab-21 Ras-related protein Rab-2 Ras-related protein Rab-2A Ras-related protein Rab-2A Ras-related protein Rab-30 Ras-related protein Rab-33 Ras-related protein Rab-35 Ras-related protein Rab-3 Ras-related protein Rab-7a Ras-related protein Rab Ras-related protein rab-11.1 Ras-related protein rab-39 Ras-related protein rab-6.1 Ras-related protein rab-6.2 small monomeric GTPase	A0A2C9C2Y0 G5EBF0 G5EBS5 G5EFA6 G5EFC1 O01803 O17788 O17789 P34213 P41992 P91857 Q18969 Q1ZXR4 Q1ZXV0 Q20365 Q21137 Q22045 Q22782 Q22908 Q23146 Q8MXS1 Q93874 Q94148 Q94986 Q9BKQ5 Q9TYY0 Q9U1W9 Q9U2C3 Q9UAQ6 Q9XWZ3	CELE_M57.2 CELE_ZK669.5 aex-6 ggtb-1 glo-1 rab-1 rab-10 rab-11.1 rab-11.2 rab-14 rab-18 rab-19 rab-21 rab-3 rab-30 rab-33 rab-35 rab-37 rab-39 rab-5 rab-6.1 rab-6.2 rab-7 rab-8 rab27 rab8 rabr-1 rabr-3 rabr-4 rep-1 rsef-1 tag-312 unc-108	Caenorhabditis elegans
Activation of AMPA receptors	GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3	A0A1T5HUM0 O01623 P34299 Q10914 Q17697 Q21415 Q8MXV8	glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7	Caenorhabditis elegans
Unblocking of NMDA receptors, glutamate binding and activation	Alpha-actinin, sarcomeric Calcium/calmodulin-dependent protein kinase type II Disks large homolog 1 EF-hand domain-containing protein GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 LITAF domain-containing protein NMDA-type ionotropic glutamate receptor NMR-2 Protein lap1	A0A1T5HUM0 G5ECY0 G5EEH3 G5EGQ9 O01623 O61967 O62305 P34299 Q10914 Q17697 Q18136 Q21415 Q23158 Q8MXV8	atn-1 cal-5 dlg-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 let-413 nmr-1 nmr-2 unc-43	Caenorhabditis elegans
Synaptic adhesion-like molecules	Disks large homolog 1 GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 LITAF domain-containing protein Muscle M-line assembly protein unc-89 NMDA-type ionotropic glutamate receptor NMR-2 Reticulon-like protein Tyrosine-protein phosphatase Lar-like Tyrosine-protein phosphatase domain-containing protein	A0A1T5HUM0 G5ECY0 G5EDI2 G5EEH3 G5EGQ9 O01623 O01761 P34299 Q10914 Q17697 Q21415 Q8MXV8 Q95XL1 Q9BMN8	CELE_Y54F10BM.3 dlg-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 nmr-1 nmr-2 ptp-3 ret-1 unc-89	Caenorhabditis elegans
Cargo concentration in the ER	Cathepsin Z-1 ERGIC-53-like protein Fibronectin type-III domain-containing protein GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 Golgi SNAP receptor complex member 2 homolog memb-1 L-type lectin-like domain-containing protein Protein cornichon homolog 1 Protein transport protein SEC23 Protein transport protein Sec24C Putative syntaxin-5 SERPIN domain-containing protein SERPIN domain-containing protein Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Small COPII coat GTPase SAR1 Vesicle-trafficking protein SEC22b Yeast SEC homolog	A0A1T5HUM0 A9Z1L1 G5ECY2 G5EDE8 G5EE40 G5EFH4 G5EGA4 G5EGP8 O01623 O17365 O45520 P34299 P41941 Q10914 Q17697 Q18287 Q19371 Q19651 Q20797 Q21415 Q22170 Q22361 Q23368 Q23445 Q8MXV8 Q94241 Q9U2Z1 Q9XVQ1	C28G1.2 CELE_F15D3.4 CELE_F44G3.7 cle-1 cni-1 cnih-2 cpz-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 gosr-2.1 ile-1 ile-2 memb-1 sar-1 sec-22 sec-23 sec-24.1 sec-24.2 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 syn-3 syx-5	Caenorhabditis elegans
COPII-mediated vesicle transport	Alpha-soluble NSF attachment protein BET1 Cathepsin Z-1 DUF727 domain-containing protein ERGIC-53-like protein Fibronectin type-III domain-containing protein GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) GLutamate Receptor family (AMPA) Gamma-soluble NSF attachment protein Glutamate receptor 1 Glutamate receptor 2 Glutamate receptor ionotropic, kainate 2 Glutamate receptor ionotropic, kainate glr-3 Golgi SNAP receptor complex member 2 homolog memb-1 Golgin subfamily A conserved domain-containing protein L-type lectin-like domain-containing protein PDZ GRASP-type domain-containing protein Probable trafficking protein particle complex subunit 2 Protein SEC13 homolog Protein cornichon homolog 1 Protein tfg-1 Protein transport protein SEC23 Protein transport protein Sec24C Protein transport protein sec-16A.1 Protein transport protein sec16 Putative syntaxin-5 RAB family Rab-GAP TBC domain-containing protein SERPIN domain-containing protein SERPIN domain-containing protein Sec1 family domain-containing protein 1 Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Small COPII coat GTPase SAR1 Trafficking protein particle complex subunit 10 Trafficking protein particle complex subunit 2-like protein Trafficking protein particle complex subunit 3 homolog Trafficking protein particle complex subunit 5 Trafficking protein particle complex subunit 6B Trafficking protein particle complex subunit 9 Trafficking protein particle complex subunit Trafficking protein particle complex subunit Uso1_p115_head domain-containing protein Vesicle-fusing ATPase Vesicle-trafficking protein SEC22b WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein YKT6 (Yeast v-SNARE) homolog Yeast SEC homolog	A0A1T5HUM0 A9Z1L1 B1GRL5 B1V899 G4SNB8 G5ECY2 G5EDE8 G5EE40 G5EEU1 G5EFH4 G5EFY6 G5EGA4 G5EGG0 G5EGP8 H2KZQ8 O01623 O02173 O17365 O45520 P34299 P34605 P34643 P41941 Q10914 Q17697 Q18287 Q18921 Q19371 Q19651 Q19989 Q1RPT8 Q20100 Q20364 Q20797 Q21115 Q21415 Q22170 Q22361 Q23368 Q23445 Q8MXV8 Q93330 Q94241 Q94392 Q9N3Y1 Q9N4A7 Q9NA81 Q9NEQ8 Q9TXZ9 Q9U1W1 Q9U2Z1 Q9UAQ6 Q9XU81 Q9XVQ1 Q9XWI2	C28G1.2 CELE_F15D3.4 CELE_F44G3.7 CELE_T10F2.5 CELE_Y42H9AR.1 CELE_Y59A8B.25 CELE_Y59A8B.8 CeSec13R cle-1 cni-1 cnih-2 cpz-1 glr-1 glr-2 glr-3 glr-4 glr-5 glr-6 glr-7 golg-2 gosr-2.1 ile-1 ile-2 memb-1 nbet-1 npp-20 nsf-1 rab-1 sar-1 sec-12 sec-13 sec-16 sec-16A.1 sec-16A.2 sec-16a.2 sec-22 sec-23 sec-24.1 sec-24.2 sec-31 sedl-1 sly-1 snap-1 srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 syn-3 syx-5 tbc-20 tfg-1 trpp-1 trpp-10 trpp-3 trpp-4 trpp-5 trpp-6 trpp-9 uso-1 ykt-6	Caenorhabditis elegans
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 Association with the SNF1 complex (ASC) domain-containing protein Association with the SNF1 complex (ASC) domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein DAF-15 GTP-binding protein Rheb homolog 1 GTP-binding protein Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Protein phosphatase ppm-1.A Ragulator complex protein LAMTOR2 homolog Ras-related GTP-binding protein C Sodium-coupled neutral amino acid transporter 9 homolog Target of rapamycin complex subunit lst8 Target of rapamycin homolog	A0A1T5HUK9 G5EGB3 H2L0K0 O02168 O17268 P34443 P45894 P91040 Q19425 Q19775 Q22743 Q68TI8 Q8I112 Q8WQG5 Q95Q95 Q95ZQ4 Q9N2U6 Q9N501 Q9NAH7 Q9XUY2	CeTor F13H10.3 aak-1 aak-2 aakb-1 aakb-2 aakg-1 aakg-2 aakg-3 aakg-4 aakg-5 daf-15 let-363 lmtr-2 lmtr-3 lmtr-5 mlst-8 ppm-1.A raga-1 ragc-1 rheb-1	Caenorhabditis elegans
Macroautophagy	5'-AMP-activated protein kinase catalytic subunit alpha-1 5'-AMP-activated protein kinase catalytic subunit alpha-2 63 kDa sperm flagellar membrane protein Association with the SNF1 complex (ASC) domain-containing protein Association with the SNF1 complex (ASC) domain-containing protein Autophagic-related protein 16.1 Autophagic-related protein 16.2 Autophagy-related protein 101 Autophagy-related protein 11 C-terminal domain-containing protein Autophagy-related protein 13 homolog Autophagy-related protein 18 Autophagy-related protein 5 Autophagy-related protein 9 Beclin homolog CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4b Charged multivesicular body protein 4b Charged multivesicular body protein 6 Charged multivesicular body protein 7 Cysteine protease atg-4.1 Cysteine protease atg-4.2 DAF-15 Dynein light chain 1, cytoplasmic Dynein light chain Dynein light chain Dynein light chain Dynein light chain Ectopic P granules protein 6 GTP-binding protein Rheb homolog 1 GTP-binding protein Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 MRG domain-containing protein Phosphatidylinositol 3-kinase catalytic subunit type 3 Probable dynein light chain 2, cytoplasmic Protein lgg-1 Protein lgg-2 Ragulator complex protein LAMTOR2 homolog Ras-related GTP-binding protein C Serine/threonine-protein kinase unc-51 Sodium-coupled neutral amino acid transporter 9 homolog Target of rapamycin complex subunit lst8 Target of rapamycin homolog UV radiation resistance-associated gene protein-like Ubiquitin-like modifier-activating enzyme ATG7 Ubiquitin-like protein atg-12 Ubiquitin-like-conjugating enzyme ATG3 non-specific serine/threonine protein kinase	A0A1T5HUK9 A0AAC1 A7DT33 G5EBK4 G5EBP5 G5EGB3 H2L0K0 K8ESC5 O02168 O02208 O16466 O17268 P34379 P34443 P45894 P91040 Q09406 Q09490 Q10931 Q18886 Q19124 Q19425 Q21557 Q21959 Q22342 Q22592 Q22718 Q22743 Q22799 Q23023 Q23536 Q23669 Q3V5I7 Q65XS9 Q68TI8 Q7YTJ8 Q86MP3 Q8I112 Q8WQG5 Q95Q95 Q95XH2 Q95ZQ4 Q9BL60 Q9GYK4 Q9N2U6 Q9N369 Q9N501 Q9NAH7 Q9TXI7 Q9TXN6 Q9U1N6 Q9U2F6 Q9XUY2 Q9XWA8 Q9XWQ4	C01A2.4 CELE_R12C12.5 CELE_Y34B4A.2 CELE_ZC247.1 CeTor F13H10.3 aak-1 aak-2 aakb-1 aakb-2 aakg-1 aakg-2 aakg-3 aakg-4 aakg-5 atg-11 atg-12 atg-13 atg-16.1 atg-16.2 atg-18 atg-3 atg-4.1 atg-4.2 atg-5 atg-6 atg-7 atg-8.1 atg-9 atgr-18 atgr-5 bec-1 chmp-7 daf-15 dlc-1 dlc-2 dlc-3 dlc-4 dlc-5 dlc-6 epg-1 epg-6 epg-7 epg-8 epg-9 let-363 let-512 lgg-1 lgg-2 lgg-3 lmtr-2 lmtr-3 lmtr-5 mlst-8 raga-1 ragc-1 rheb-1 tag-283 unc-51 vps-15 vps-2 vps-20 vps-24 vps-32.1 vps-34	Caenorhabditis elegans
Deactivation of the beta-catenin transactivating complex	14-3-3-like protein 1 14-3-3-like protein 2 Adenomatous polyposis coli protein-related protein 1 Beta-catenin-like protein hmp-2 C-terminal-binding protein 1 Chromodomain and Helicase Domain protein HMG box domain-containing protein Histone deacetylase Importin N-terminal domain-containing protein Protein pop-1 Transcription factor egl-13 Transcription factor sem-2 Transcription factor sox-2 Transcription factor sox-3 Transcription factor unc-37	A0A1N7SZG1 G5ECH0 O02482 O44326 O61845 P41932 Q10666 Q20201 Q20595 Q20655 Q21227 Q21305 Q23045 Q23089 Q8T3B9	apr-1 chd-7 cog-2 ctbp-1 egl-13 esg ftt-1 ftt-2 hda-3 hmp-2 par-5 pop-1 sem-2 sox-2 sox-3 sox-4 unc-37 xpo-1	Caenorhabditis elegans
Neurotransmitter receptors and postsynaptic signal transmission	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor (51.1 kD) (Acr-22) Acetylcholine receptor subunit alpha-type acr-5 Acetylcholine receptor subunit alpha-type deg-3 Acetylcholine receptor subunit alpha-type des-2 Acetylcholine-gated chloride channel subunit acc-1 Acetylcholine-gated chloride channel subunit acc-2 Acetylcholine-gated chloride channel subunit acc-3 Acetylcholine-gated ion channel acc-4 Betaine receptor acr-23 Glutamate-gated ChLoride channel Glutamate-gated chloride channel alpha Glutamate-gated chloride channel subunit beta Glutamate-gated chloride channel subunit Glycine receptor subunit beta-type 4 Ig-like domain-containing protein Ig-like domain-containing protein Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-Gated ion Channel Ligand-gated ion channel 4 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Ligand-gated ion channel 50 Neur_chan_LBD domain-containing protein Neur_chan_LBD domain-containing protein Neur_chan_memb domain-containing protein Neur_chan_memb domain-containing protein Neurotransmitter-gated ion-channel ligand binding domain protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Probable ligand-gated ion channel 46 Serotonin-gated chloride channel mod-1	A0A1N7SYW0 A0A3P6P985 A0A4V0IK40 A0A4V0IN81 B1Q281 G5EBR3 G5ECH3 G5EDN0 G5EE87 G5EEC1 G5EEX8 G5EEZ3 G5EG88 G5EGR1 H2KML8 H2KYN9 O17041 O17274 O17402 O18228 O44452 O61216 O61519 O61520 O76554 P41849 P54244 P54245 P54246 P90876 P91985 Q09453 Q10052 Q17328 Q18812 Q21005 Q21420 Q22588 Q22741 Q6BEQ0 Q95Q97 Q95QT7 Q95Y52 Q95Y94 Q9GQ00 Q9N517 Q9NA62 Q9U358 V6CJ96 X5LVB0	acc-1 acc-2 acc-3 acc-4 acr-20 acr-21 acr-22 acr-23 acr-24 acr-4 acr-5 avr-14 avr-15 deg-3 des-2 gbr-4 ggr-1 ggr-2 ggr-3 glc-1 glc-2 glc-3 glc-4 lgc-10 lgc-11 lgc-12 lgc-30 lgc-31 lgc-32 lgc-34 lgc-39 lgc-4 lgc-40 lgc-41 lgc-42 lgc-44 lgc-45 lgc-46 lgc-47 lgc-48 lgc-49 lgc-5 lgc-50 lgc-51 lgc-52 lgc-53 lgc-54 lgc-55 lgc-56 lgc-58 lgc-6 lgc-7 lgc-8 lgc-9 mod-1	Caenorhabditis elegans

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