GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	November 12, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **435** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Aspartate and asparagine metabolism	Asparagine synthetase [glutamine-hydrolyzing] Aspartate aminotransferase, cytoplasmic Aspartate aminotransferase Glutamate carboxypeptidase 2 homolog N-acetylated-alpha-linked acidic dipeptidase 2 Probable calcium-binding mitochondrial carrier K02F3.2 asparaginase	O16924 P91406 Q17994 Q21153 Q22067 Q93332 Q9U3P0	C27A7.5 K02F3.2 asns-1 gcp-2.1 gcp-2.2 got-1 got-1.2 got-2.2	Caenorhabditis elegans
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Derlin-1 E3 ubiquitin-protein ligase hrd-like protein 1 Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Polyubiquitin-A Probable 26S proteasome regulatory subunit 4 Transitional endoplasmic reticulum ATPase homolog 2 UBX domain-containing protein 1 UV excision repair protein RAD23 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	O16368 P0CG71 P37165 P49632 P54812 P90859 Q23451 Q93561 Q9TW67 Q9TXH9	cdc-48.2 cup-2 der-1 hrdl-1 png-1 rad-23 rpt-2 ubia ubib ubl-1 ubq-1 ubq-2 ubxn-1	Caenorhabditis elegans
Heme degradation	ABC transmembrane type-1 domain-containing protein ABC transporter domain-containing protein ABC transporter family G domain-containing protein Fatty acid-binding protein homolog 5 Fatty acid-binding protein homolog 6 Fatty acid-binding protein homolog 7 Fatty acid-binding protein homolog 8 Multidrug resistance protein mrp-7 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 1 Solute carrier organic anion transporter family member	D7SFK1 G5EFP3 O01812 O01814 O02323 O02324 Q19048 Q19585 Q20943 Q3S1M2 Q93550 Q9U2G5 Q9XW61	CELE_F21G4.1 abcx-1 lbp-5 lbp-6 lbp-7 lbp-8 mrp-1 mrp-2 mrp-3 mrp-4 mrp-7 mrp-8 wht-5	Caenorhabditis elegans
Clathrin-mediated endocytosis	AP complex subunit beta AP complex subunit sigma AP-2 complex subunit alpha AP-2 complex subunit mu Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2 Actin-related protein 3 Amphiphysin Beta-arrestin arr-1 C2 domain-containing protein C2 domain-containing protein C2 domain-containing protein C2 domain-containing protein Clathrin light chain DiSHevelled related DiSHevelled related Dynamin E3 ubiquitin-protein ligase CBL EGF-like domain-containing protein EGF-like domain-containing protein EHS-1 ENTH domain-containing protein Endophilin-A homolog FCH domain only protein 2 Frizzled-4 G-protein coupled receptors family 1 profile domain-containing protein Heat shock protein hsp-1 Hepatocyte growth factor-regulated tyrosine kinase substrate Huntington interacting protein related 1 Intersectin-1 J domain-containing protein Multidrug resistance-associated protein lethal(2)03659 Muscarinic acetylcholine receptor gar-3 NECAP PHear domain-containing protein PIPK domain-containing protein Phosphatidylinositol-binding clathrin assembly protein unc-11 Polyubiquitin-A Probable G-protein coupled receptor tkr-1 Probable actin-related protein 2/3 complex subunit 2 Probable actin-related protein 2/3 complex subunit 3 Probable actin-related protein 2/3 complex subunit 4 Probable clathrin heavy chain 1 Protein Wnt-2 Putative stoned B-like protein Receptor tyrosine-protein kinase let-23 Receptor-mediated endocytosis protein 6 Rho-GAP domain-containing protein SH3 domain-containing protein SH3 domain-containing protein Segment polarity protein dishevelled homolog mig-5 Sensory neuron membrane protein 2 Sex muscle abnormal protein 5 Signal transducing adapter molecule 1 Sorting nexin lst-4 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptojanin Synaptotagmin 2 Synaptotagmin-1 Transducer of Cdc42-dependent actin assembly protein 1 homolog Transducer of Cdc42-dependent actin assembly protein 2 homolog Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein Vesicular acetylcholine transporter unc-17 small monomeric GTPase	A0A0K3AS36 A0A0K3AUI8 A0A3P6PCS5 A0A486WXP9 B1V8A0 G5EBK2 G5ECL2 G5EDV1 G5EFK8 K8FE10 O01498 O01759 O02495 O16700 O17590 O18014 O44191 O61861 P09446 P0CG71 P24348 P29355 P34351 P34574 P34693 P34711 P34889 P35603 P37165 P39055 P49632 P51485 P53489 P58798 P90761 P90961 P91493 P91857 Q02328 Q03566 Q17796 Q18239 Q19019 Q19123 Q19136 Q19253 Q19625 Q19767 Q21004 Q22227 Q22601 Q23056 Q6A573 Q6AHQ8 Q8I4E2 Q8WTM6 Q94057 Q95XH1 Q9BI71 Q9BIF4 Q9GYH7 Q9N489 Q9N4F3 Q9N4I0 Q9TXS0 Q9U7D5 Q9XTT3 Q9XUS7 Q9XWV3 Q9XZI6	CELE_F14B4.1 CELE_T27E4.1 amph-1 ap50 apa-2 apb-1 aps-2 apt-10 arp-2 arr-1 arx-1 arx-2 arx-3 arx-4 arx-5 arx-6 arx-7 cdap-2 chc-1 clic-1 cwn-2 dnj-25 dpy-23 dsh-1 dsh-2 dyn-1 ehs-1 epn-1 fcho-1 gar-3 hgrs-1 hipr-1 hsp-1 hsp70a itsn-1 kin-7 let-23 lin-17 lst-4 mig-5 mrp-6 ncap-1 npr-25 ocrl-1 ppk-1 pqn-19 rab-5 rme-2 rme-6 scav-3 sdpn-1 sem-5 sli-1 snb-1 snb-2 snb-5 snb-6 snb-7 snt-1 snt-2 snt-4 snt-5 stam-1 sue-1 tkr-1 toca-1 toca-2 ubia ubib ubl-1 ubq-1 ubq-2 unc-11 unc-17 unc-26 unc-41 unc-57 vamp-7 wnt-2	Caenorhabditis elegans
NCAM signaling for neurite out-growth	Inactive tyrosine-protein kinase kin-32 Mitogen-activated protein kinase mpk-1 Putative ribosomal protein S6 kinase alpha-2 Ras protein let-60 Sex muscle abnormal protein 5 Son of sevenless homolog Spectrin alpha chain Spectrin beta chain Spectrin beta chain Tyrosine protein-kinase src-1 Tyrosine-protein phosphatase Lar-like Uncharacterized protein C50C3.2	E0AHA7 G5EE56 G5EFW3 P22981 P29355 P34367 P39745 Q18846 Q21408 Q95YD4 Q9BMN8 Q9N5D3	C50C3.2/C50C3.3 kin-32 let-341 let-60 lin-34 mpk-1 ptp-3 rskn-2 sem-5 sma-1 sos-1 spc-1 src-1 sur-1 unc-70	Caenorhabditis elegans
GABA receptor activation	Gamma-aminobutyric acid receptor exp-1 Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Gamma-aminobutyric acid receptor subunit beta Ligand-Gated ion Channel Ligand-Gated ion Channel Neurotransmitter-gated ion-channel ligand-binding domain-containing protein	A0A3P6NNS2 G5ECD3 G5ECJ0 G5ECN1 O18276 Q6BET0 Q7YTP9 Q9U2E2	exp-1 gab-1 lgc-35 lgc-36 lgc-37 lgc-38 lgc-43 unc-49 unc-49B	Caenorhabditis elegans
Stimuli-sensing channels	Acid-sensing ion channel 1-like Acid-sensing ion channel 1 Amiloride-sensitive sodium channel Amiloride-sensitive sodium channel Anoctamin Band 7 domain-containing protein Cation/H+ exchanger domain-containing protein Cation/H+ exchanger domain-containing protein Cation/H+ exchanger domain-containing protein Chloride channel protein clh-3 Chloride channel protein Chloride channel protein Chloride channel protein Chloride channel protein Coelomocyte uptake defective protein 15 DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Like DEgenerin Linked to Mechanosensation DEgenerin Linked to Mechanosensation Degenerin deg-1 Degenerin del-1 Degenerin mec-10 Degenerin mec-4 Degenerin unc-8 Degenerin-like protein asic-1 Degenerin-like protein asic-2 Degenerin-like protein del-10 Degenerin-like protein unc-105 E3 ubiquitin-protein ligase wwp-1 E3 ubiquitin-protein ligase EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein EGF-like domain-containing protein FLR-1 Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Polyubiquitin-A Protein tweety homolog 1 Raf homolog serine/threonine-protein kinase Serine/threonine-protein kinase sgk-1 Stomatin-1 Stomatin-2 Stomatin-3 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Uncharacterized transporter slc-17.2 Uncharacterized transporter slc-17.3	A0A061ACQ8 G3MU02 G5EC75 G5EFH3 G5EFS0 G5EG93 G5EGI5 G5EGT4 H2KYN8 H2KZQ1 H2L0J1 H2L2L3 O01537 O01635 O01664 O44130 O45402 P0CG71 P24585 P24612 P34272 P34886 P37165 P49632 P91100 P91102 P91103 P91835 Q03567 Q07292 Q09274 Q09322 Q10025 Q10048 Q18077 Q18651 Q19038 Q19200 Q19777 Q19958 Q20273 Q20332 Q20657 Q20852 Q21974 Q22851 Q22970 Q23514 Q23576 Q2PJ68 Q7YZV6 Q8I4F6 Q8MPW0 Q93205 Q93597 Q9BMK9 Q9N2Z7 Q9U1T8 Q9U1T9 Q9XTS9 Q9XU88	C38C10.2 CELE_F41E7.2 CELE_Y92H12A.2 acd-1 acd-2 acd-3 acd-4 acd-5 anoh-2 asic-1 asic-2 cima-1 clc-3 clh-2 clh-3 clh-4 clh-5 clh-6 cup-15 deg-1 degt-1 del-1 del-10 del-3 del-4 del-5 del-6 del-7 del-8 del-9 delm-1 delm-2 egas-1 egas-2 egas-3 egas-4 flr-1 lin-45 mec-10 mec-13 mec-4 raf-1 sgk-1 slc-17.1 slc-17.3 slc-17.4 slc-17.5 slc-17.6 slc-17.7 slc-17.8 slc-17.9 slc-9B.1 slc-9B.2 slc-9b.1 slc-9b.2 sto-1 sto-2 sto-3 sto-5 ttyh-1 ubia ubib ubl-1 ubq-1 ubq-2 unc-105 unc-8 wwp-1	Caenorhabditis elegans
Regulation of TLR by endogenous ligand	BPI1 domain-containing protein BPI2 domain-containing protein BPI2 domain-containing protein BPI2 domain-containing protein High mobility group protein 1.2 Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Lipid-binding serum glycoprotein C-terminal domain-containing protein Nose resistant to fluoxetine protein 5 Uncharacterized protein T19C3.5	A8WFJ7 H9G2Z8 O17768 Q09390 Q10011 Q17654 Q17738 Q18869 Q20380 Q23365 Q93796	C05C9.1 C06E8.5 C06G1.1 C55C3.1 CELE_F01G10.10 CELE_F10D11.6 CELE_F44A2.3 CELE_ZC513.2 T19C3.5 hmg-1.2 nrf-5	Caenorhabditis elegans
trans-Golgi Network Vesicle Budding	ADP-ribosylation factor 1-like 1 ADP-ribosylation factor 1-like 2 E3 ubiquitin-protein ligase arc-1 Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 homolog Putative syntaxin-2 Synaptobrevin-1 Synaptobrevin-like protein 5 Synaptosomal-associated protein Syntaxin-1A homolog V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein V-SNARE coiled-coil homology domain-containing protein t-SNARE protein aex-4	A5PEW5 G5EBK2 G5EEN8 G5EGS5 O02495 O16000 P34351 Q09654 Q10943 Q19767 Q20574 Q94057 Q94231 Q95XH1	aex-4 arc-1 arf-1 arf-1.1 arf-1.2 arl-4 arl-6 gbf-1 phi-34 ric-4 snb-1 snb-2 snb-5 snb-6 snb-7 syn-2 syx-2 tag-81 unc-64 vamp-7	Caenorhabditis elegans
RUNX3 regulates CDKN1A transcription	BMP-like protein unc-129 Dauer larva development regulatory growth factor daf-7 Dwarfin sma-4 Protein dbl-1 Runt-related transcription factor rnt-1 Smad protein daf-8 Zinc Finger and Homeobox	G5EBY8 G5EEL5 G5EFQ5 P45897 P92172 Q21733 V6CLN5	cem-3 cet-1 daf-7 daf-8 dbl-1 mab-2 rnt-1 run-1 sma-4 unc-129 zfh-2	Caenorhabditis elegans
Regulation of IGF Activity by IGFBP	Amyloid-beta-like protein Anoctamin Apolipoprotein L, 1 Apolipoprotein L3-like BMP-like protein unc-129 Calumenin-like protein Cystatin cpi-2 DUF19 domain-containing protein Dauer larva development regulatory growth factor daf-7 Disintegrin and metalloproteinase domain-containing protein 10 homolog EGL-17 Endoplasmin homolog Extracellular serine/threonine protein kinase CeFam20 Fibronectin type-III domain-containing protein Galectin domain-containing protein Glucosidase 2 subunit beta J domain-containing protein Multiple epidermal growth factor-like domains protein 6 NTR domain-containing protein NUCleoBindin homolog Nidogen PNPLA domain-containing protein PNPLA domain-containing protein Patatin-like phospholipase domain-containing protein atgl-1 Probable syndecan Protein dbl-1 Protein disulfide-isomerase 1 Protein disulfide-isomerase 2 Protein disulfide-isomerase A6 homolog Putative alpha-L-fucosidase Putative metalloproteinase inhibitor tag-225 SERPIN domain-containing protein SERPIN domain-containing protein SPARC Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serine or cysteine protease inhibitor Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Serpin domain-containing protein Sulfhydryl oxidase Thioredoxin domain-containing protein Transmembrane protein 132 homolog VWFA domain-containing protein	A9Z1L1 G5EBH7 G5EBY8 G5EC87 G5ECM9 G5ECY2 G5EE40 G5EEF1 G5EEL5 G5EFD9 G5EFH4 G5EFX3 H2FLL2 H2KZY5 H2L2L3 O17365 O45520 P34714 P49713 P50605 P91189 P92172 Q09EE8 Q10651 Q11067 Q11186 Q17770 Q17967 Q18048 Q18096 Q18287 Q18948 Q19651 Q20684 Q21265 Q21267 Q22235 Q8MQ51 Q8WQF7 Q8WQF8 Q93791 Q9BL47 Q9N5Z7 Q9XTW2 Q9XVQ1	B0524.2 C16E9.1 C18E9.7 C28G1.2 CELE_D1054.1 CELE_F07F6.7 CELE_F07F6.8 CELE_F15D3.4 CELE_F44G3.7 CELE_F47B7.2 CELE_M04D5.1 CELE_W01A8.8 CELE_Y64G10A.7 CELE_ZK1307.8 W03G11.3 Y71H2AM.10 anoh-2 apl-1 atgl-1 calu-1 cet-1 cpi-2 daf-7 dbl-1 dnj-7 egl-17 enpl-1 famk-1 lec-2 nid-1 nucb-1 ost-1 pdi-1 pdi-2 pdi-6 sdn-1 sparc srp-1 srp-2 srp-3 srp-6 srp-7 srp-8 sup-17 tag-225 tag-320 timp-1 unc-129	Caenorhabditis elegans
Antimicrobial peptides	BPI1 domain-containing protein C-type lectin domain-containing protein 161 C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein C-type lectin domain-containing protein Phospholipase A2 Phospholipase A2 Phospholipase A2	G4RY15 H9G2Z8 O16654 P34472 P91429 Q17450 Q17452 Q17790 Q22591 Q3V5J7 Q9TZ75 Q9XUL6 Q9XUL7 Q9XVE1	C03H5.4 C07E3.9 CELE_F10D11.6 CELE_Y69A2AL.2 clec-148 clec-161 clec-178 clec-48 clec-49 clec-50 clec-51 clec-52 clec-53 clec-89	Caenorhabditis elegans
Glycosaminoglycan metabolism	UDP-glucuronate decarboxylase	G5EF65	sqv-1	Caenorhabditis elegans
Carnitine shuttle	5'-AMP-activated protein kinase catalytic subunit alpha-2 Association with the SNF1 complex (ASC) domain-containing protein Association with the SNF1 complex (ASC) domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein CBS domain-containing protein Calponin-homology (CH) domain-containing protein Carnitine O-palmitoyltransferase Choline/carnitine acyltransferase domain-containing protein Choline/carnitine acyltransferase domain-containing protein Choline/carnitine acyltransferase domain-containing protein Choline/carnitine acyltransferase domain-containing protein Choline/carnitine acyltransferase domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Major facilitator superfamily (MFS) profile domain-containing protein Nuclear hormone receptor family member nhr-2 Nuclear hormone receptor family member nhr-7 Nuclear hormone receptor family member nhr-85 Nuclear hormone receptor family member nhr-91 Nuclear hormone receptor unc-55 Organic cation transporter 1 Protein dif-1 Putative transporter B0252.3 Putative transporter B0361.11 Steroid hormone receptor family member cnr14 Uncharacterized protein F23F12.3	A0A0K3AVV4 A0A0K3AWD3 A0A1T5HUK9 A0A238UKL7 G5ECR9 G5ECS9 G5EDA7 G5EEI9 G5EG54 G5EGL6 H2L0K0 O02168 O16992 O18247 O44619 P41830 P46499 Q09617 Q10902 Q10917 Q18613 Q18655 Q18795 Q19442 Q20765 Q22686 Q23066 Q23501 Q27257 Q4PIX1 Q7Z118 Q8I112 Q95ZQ4 Q9BKR9 Q9N3N3 Q9N501 Q9NAH7 Q9U2F2 Q9U2R6 Q9U539 Q9UAW9 Q9XUK7 Q9XUY2	B0252.3 B0361.11 C06H5.6 C44C10.3 C46C2.2 CELE_F23F12.13 CELE_F45E10.2 CELE_K05F1.6 CELE_K09E9.1 CELE_K11D9.3 CELE_T08B1.1 CELE_T12B3.2 CELE_T22F7.1 CELE_W03F9.4 CELE_Y57G11C.23 CELE_Y82E9BR.16 CELE_ZK892.3 F23F12.3/F23F12.1 aak-2 aakb-1 aakb-2 aakg-1 aakg-2 aakg-3 aakg-4 aakg-5 cnr-14 cpt-1 cpt-2 cpt-3 cpt-4 cpt-5 cpt-6 dif-1 nhr-2 nhr-24 nhr-7 nhr-85 nhr-91 nr1g1 oct-1 oct-2 pes-23 sex-1 suex-2 unc-55	Caenorhabditis elegans
Transferrin endocytosis and recycling	CUP-5L Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit S1 V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q22494 Q23680 Q8T666 Q95X44 Q95YD5 Q9N5A0 Q9TYW1 Q9XW92 Q9XXU9	cup-5 fus-1 rdy-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-19 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
MET Receptor Activation	Kringle domain-containing protein Protein kinase domain-containing protein Tyrosine-protein kinase receptor svh-2	H2KZU7 P91823 Q9XVQ7	CELE_F11E6.8 CELE_T22A3.6 svh-2	Caenorhabditis elegans
Phase 4 - resting membrane potential	IRK_C domain-containing protein Inward rectifier potassium channel irk-1 Inward rectifier potassium channel irk-1 Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein Potassium channel domain-containing protein TWiK family of potassium channels protein 18 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9 Uncharacterized protein B0310.1	A0A1C3NSK2 A0A1C3NSN6 A1EHR5 F5GUD1 G5EBQ2 G5ECW6 G5EG92 G5EGD4 H2KZ66 O17185 O45422 O45891 O45894 P52192 Q10937 Q18120 Q21467 Q22042 Q22043 Q23297 Q65XY3 Q6BES3 Q6EUT8 Q9BL31 Q9NEV3 Q9XTV6 U4PFA8	B0310.1 irk-1 irk-2 irk-3 irk-4 sup-9 twk-1 twk-11 twk-14 twk-18 twk-20 twk-21 twk-22 twk-24 twk-25 twk-26 twk-31 twk-33 twk-34 twk-35 twk-36 twk-39 twk-42 twk-44 twk-45 twk-46 twk-49 twk-8	Caenorhabditis elegans
Localization of the PINCH-ILK-PARVIN complex to focal adhesions	Integrin-linked protein kinase homolog pat-4 Uncharacterized integrin beta-like protein C05D9.3	Q9GYK2 Q9TZC4	C05D9.3 pat-4	Caenorhabditis elegans
Depolymerization of the Nuclear Lamina	CTD nuclear envelope phosphatase 1 homolog Cyclin N-terminal domain-containing protein Cyclin-dependent kinase 1 G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B Intermediate filament protein ifa-1 Intermediate filament protein ifa-2 Intermediate filament protein ifa-3 Intermediate filament protein ifa-4 Intermediate filament protein ifb-1 Intermediate filament protein ifb-2 Intermediate filament protein ifc-1 Intermediate filament protein ifc-2 Intermediate filament protein ifd-1 Intermediate filament protein ifd-2 Intermediate filament protein ifp-1 LNS2/PITP domain-containing protein Lamin-1 Nuclear envelope phosphatase-regulatory subunit 1 homolog Protein kinase C-like 2	O02365 O45168 O45926 P34556 P90900 P90901 P90980 Q09501 Q10653 Q19286 Q19289 Q19782 Q20432 Q21065 Q21067 Q21443 Q86DC6 Q9BLB5 Q9XXN3 Q9XXT5	cdk-1 cnep-1 cyb-1 cyb-2.1 cyb-2.2 ifa-1 ifa-2 ifa-3 ifa-4 ifb-1 ifb-2 ifc-1 ifc-2 ifd-1 ifd-2 ifp-1 kin-11 lam-1 lmn-1 lpin-1 mua-6 ncc-1 nepr-1 pkc-2 scpl-2	Caenorhabditis elegans
Ion channel transport	Probable V-type proton ATPase subunit F Probable V-type proton ATPase subunit G Probable V-type proton ATPase subunit H 2 V-type proton ATPase 116 kDa subunit a 1 V-type proton ATPase 116 kDa subunit a 2 V-type proton ATPase 116 kDa subunit a 3 V-type proton ATPase 116 kDa subunit a 4 V-type proton ATPase 16 kDa proteolipid subunit c 2 V-type proton ATPase 16 kDa proteolipid subunit c 3 V-type proton ATPase 21 kDa proteolipid subunit c'' V-type proton ATPase catalytic subunit A V-type proton ATPase subunit B 1 V-type proton ATPase subunit B 2 V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit S1 V-type proton ATPase subunit e V-type proton ATPase subunit	B2MZD0 C0HLB3 C0HLB4 G5EDB8 G5EEK9 G5EGP4 P30628 P34462 P91303 Q19626 Q20591 Q22494 Q23680 Q95X44 Q95YD5 Q9N5A0 Q9TYW1 Q9XW92 Q9XXU9	fus-1 rdy-1 spe-5 unc-32 vha-10 vha-11 vha-12 vha-13 vha-14 vha-15 vha-16 vha-17 vha-19 vha-2 vha-3 vha-4 vha-5 vha-6 vha-7 vha-8 vha-9	Caenorhabditis elegans
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)	BMP-like protein unc-129 Cell surface receptor daf-1 Cell surface receptor daf-4 DH domain-containing protein Dauer larva development regulatory growth factor daf-7 Partitioning defective protein 3 Partitioning defective protein 6 Polyubiquitin-A Protein dbl-1 Protein kinase C-like 3 Ras-like GTP-binding protein rhoA Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	A0A0K3AQN0 G5EBY8 G5EEL5 P0CG71 P20792 P37165 P49632 P50488 P92172 Q17353 Q19266 Q22038 Q9NAN2	aPKC cet-1 daf-1 daf-4 daf-7 dbl-1 par-3 par-6 pkc-3 rhgf-3 rho-1 rhoa ubia ubib ubl-1 ubq-1 ubq-2 unc-129	Caenorhabditis elegans
TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain	Geranylgeranyl transferase type-2 subunit alpha Probable geranylgeranyl transferase type-2 subunit beta Rab proteins geranylgeranyltransferase component A 1	P41992 Q9BKQ5 Q9TYY0	CELE_M57.2 ggtb-1 rep-1	Caenorhabditis elegans
Pre-NOTCH Processing in Golgi	CUB domain-containing protein EGF-like domain-containing protein Protein lin-12 Suppressor/enhancer of lin-12 protein 9	O17528 P14585 P90891 Q21850	CELE_F55H12.3 CELE_R08E3.1 lin-12 sel-9	Caenorhabditis elegans
Adrenaline signalling through Alpha-2 adrenergic receptor	Tyramine receptor Ser-2 Tyramine receptor tyra-2	O02213 Q19084	ser-2 tyra-2	Caenorhabditis elegans
TGFBR3 regulates TGF-beta signaling	BMP-like protein unc-129 Beta-arrestin arr-1 Cell surface receptor daf-4 Dauer larva development regulatory growth factor daf-7 Protein dbl-1	G5EBY8 G5EEL5 P50488 P51485 P92172	arr-1 cet-1 daf-4 daf-7 dbl-1 unc-129	Caenorhabditis elegans

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