GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **499** in total

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Pathway Name	Protein Name	UniProt ID ▼	Gene Symbol	Organism	GlyTouCan ID
DCC mediated attractive signaling	CED-5 CRAL-TRIO domain-containing protein Cell division control protein 42 homolog Homeobox protein ceh-6 Inactive tyrosine-protein kinase kin-32 NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Netrin receptor unc-40 Ras-related protein ced-10 Tyrosine protein-kinase src-1	G5EE56 G5EEN3 G5EF96 O61528 P20268 Q03206 Q05062 Q95PX0 Q95YD4	cdc-42 ced-10 ced-5 ceh-6 kin-32 nck-1 rac-1 src-1 unc-40 unc-73	Caenorhabditis elegans
Ephrin signaling	Arf-GAP domain-containing protein Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin RBD domain-containing protein Ephrin receptor 1 Ephrin-4 Myosin regulatory light chain NCK (Non-Catalytic region of tyrosine Kinase) adaptor protein family Ras-related protein ced-10 SH2 domain-containing protein SH3 domain-containing protein Serine/threonine-protein kinase max-2 Serine/threonine-protein kinase pak-1 Tyrosine protein-kinase src-1	G5EE56 G5EEE7 G5EGQ3 O44516 O61460 Q03206 Q09510 Q17850 Q19467 Q19475 Q21430 Q95PX0 Q95XA9 Q9U3M2	ced-10 efn-2 efn-3 efn-4 gap-3 git-1 mab-26 max-2 mlc-4 nck-1 pak-1 pix-1 rac-1 src-1 vab-1 vab-2	Caenorhabditis elegans
Negative regulation of the PI3K/AKT network	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 Protein nipi-3 Serine/threonine-protein kinase akt-1 Serine/threonine-protein kinase akt-2	G5EE01 G5EED4 Q17941 Q9XTG7	akt-1 akt-2 daf-18 nipi-3	Caenorhabditis elegans
FGFR1c ligand binding and activation	EGL-17 Myoblast growth factor receptor egl-15 Protein let-756 WAP-type 'four-disulfide core	G5EDX1 G5EEF1 Q10656 Q11184	egl-15 egl-17 kal-1 let-756	Caenorhabditis elegans
Negative regulation of FGFR1 signaling	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Mitogen-activated protein kinase mpk-1 Myoblast growth factor receptor egl-15 Protein let-756 WAP-type 'four-disulfide core	G5EDX1 G5EEF1 P39745 Q10656 Q11184 Q18758 Q9TZA0	egl-15 egl-17 kal-1 klo-1 klo-2 let-756 mpk-1 sur-1	Caenorhabditis elegans
U12 Dependent Splicing	CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein CSD domain-containing protein DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit rpb-9 DNA-directed RNA polymerase RpoA/D/Rpb3-type domain-containing protein DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription factor IIF subunit 2 Nuclear cap-binding protein subunit 1 Nuclear cap-binding protein subunit 2 PSP proline-rich domain-containing protein Pre-mRNA-processing factor 6 Pre-mRNA-splicing factor 8 homolog Probable DNA-directed RNA polymerase II subunit RPB11 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC2 Probable DNA-directed RNA polymerases I, II, and III subunit RPABC3 Probable small nuclear ribonucleoprotein E Probable small nuclear ribonucleoprotein F Probable small nuclear ribonucleoprotein G Probable small nuclear ribonucleoprotein Sm D1 Probable small nuclear ribonucleoprotein Sm D2 Probable small nuclear ribonucleoprotein-associated protein B Probable splicing factor, arginine/serine-rich 2 Probable splicing factor, arginine/serine-rich 3 Probable splicing factor, arginine/serine-rich 4 Probable splicing factor, arginine/serine-rich 6 RNA helicase RNA helicase RNA polymerase Rpb4/RPC9 core domain-containing protein Small nuclear ribonucleoprotein Sm D3 Splicing factor 3B subunit 1 domain-containing protein Splicing factor 3B subunit 3 Splicing factor 3B subunit 4 Thioredoxin-like protein Tr-type G domain-containing protein Transcription initiation factor IIF subunit alpha U5 small nuclear ribonucleoprotein 200 kDa helicase WD_REPEATS_REGION domain-containing protein WD_REPEATS_REGION domain-containing protein	G5EDV3 G5EEQ8 L8E6I4 O01763 O02092 O02097 O16997 O44985 O62213 P16356 P34369 P34659 P91306 P91398 P91918 Q09442 Q09511 Q10013 Q10578 Q17348 Q17558 Q17684 Q18409 Q18786 Q19211 Q19826 Q23120 Q23463 Q8MYM8 Q93338 Q93382 Q93594 Q95QN2 Q965S0 Q9GR61 Q9GRZ2 Q9N3C9 Q9N4G9 Q9N5K2 Q9NEW6 Q9U2G0 Q9U3I0 Q9XTU6 Q9XVH6	C46F11.4 ama-1 cbp-20 cbp-80 cey-1 cey-2 cey-3 cey-4 ddx-23 dib-1 eftu-2 gtf-2F1 gtf-2F2 gtf-2f1 gtf-2f2 ncbp-1 ncbp-2 prp-6 prp-8 rpb-1 rpb-10 rpb-11 rpb-12 rpb-2 rpb-3 rpb-4 rpb-5 rpb-6 rpb-7 rpb-8 rpb-9 rsp-2 rsp-3 rsp-4 rsp-6 sap-49 sftb-1 sftb-2 snr-1 snr-2 snr-3 snr-4 snr-5 snr-6 snr-7 snrp-200 snrp-40.1 snrp-40.2 srp-1 srp-2 srp-4 teg-4	Caenorhabditis elegans
Role of phospholipids in phagocytosis	PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein PLD phosphodiesterase domain-containing protein Phospholipase Probable phospholipase D F09G2.8 Protein kinase C-like 1 Protein kinase C-like 1B phospholipase A2	G5EDU3 H2KZ05 O17405 P34722 P34885 Q19056 Q8I4C7 Q95YD2	C45B2.6 CELE_E04F6.4 CELE_T05C3.6 CELE_Y51A2D.13 F09G2.8 PLD kin-13 pkc-1 pld-1 tpa-1 ttx-4	Caenorhabditis elegans
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Cyclin-C Cyclin-T1.1 Cyclin-T1.2 Cyclin-dependent kinase 8 Cyclin-like domain-containing protein Dwarfin sma-4 E2F/DP family winged-helix DNA-binding domain-containing protein Furin-like protease kpc-1 Mitogen-activated protein kinase mpk-1 Mothers against decapentaplegic homolog Polyubiquitin-A Probable cyclin-dependent kinase 9 Retinoblastoma-like protein homolog lin-35 Smad protein daf-8 Transcription factor dpl-1 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein Yes-associated protein homolog 1	G5EDS9 G5EDT1 G5EF11 O17798 O17869 P0CG71 P34424 P34425 P37165 P39745 P45897 P49632 P90866 Q19404 Q21733 Q22703 Q9TVL3 Q9TYP2	ccnk-1 cdk-8 cdk-9 cem-3 cic-1 cit-1.1 cit-1.2 daf-8 dpl-1 efl-1 kpc-1 lin-35 mpk-1 sma-4 sur-1 tag-68 ubia ubib ubl-1 ubq-1 ubq-2 yap-1	Caenorhabditis elegans
MET activates PI3K/AKT signaling	Kringle domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein kinase domain-containing protein Sex muscle abnormal protein 5 Tyrosine-protein kinase receptor svh-2	G5EDP9 H2KZU7 P29355 P91823 Q94125 Q9XVQ7	CELE_F11E6.8 CELE_T22A3.6 aap-1 age-1 sem-5 svh-2	Caenorhabditis elegans
GAB1 signalosome	EGF-like domain-containing protein EGF-like domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Receptor tyrosine-protein kinase let-23	G5EDP9 G5EFK8 O44191 P24348 Q94125	CELE_F14B4.1 aap-1 age-1 kin-7 let-23 rme-2	Caenorhabditis elegans
PI3K events in ERBB2 signaling	EGF-like domain-containing protein EGF-like domain-containing protein Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Receptor tyrosine-protein kinase let-23 Sex muscle abnormal protein 5	G5EDP9 G5EFK8 O44191 P24348 P29355 Q94125	CELE_F14B4.1 aap-1 age-1 kin-7 let-23 rme-2 sem-5	Caenorhabditis elegans
PI-3K cascade:FGFR4	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein let-756 Sex muscle abnormal protein 5	G5EDP9 G5EEF1 P29355 Q10656 Q11184 Q18758 Q94125 Q9TZA0	aap-1 age-1 egl-15 egl-17 klo-1 klo-2 let-756 sem-5	Caenorhabditis elegans
PI-3K cascade:FGFR1	EGL-17 Glycoside hydrolase family 1 protein Glycoside hydrolase family 1 protein Myoblast growth factor receptor egl-15 Phosphatidylinositol 3-kinase age-1 Phosphoinositide 3-kinase adapter subunit Protein let-756 Sex muscle abnormal protein 5	G5EDP9 G5EEF1 P29355 Q10656 Q11184 Q18758 Q94125 Q9TZA0	aap-1 age-1 egl-15 egl-17 klo-1 klo-2 let-756 sem-5	Caenorhabditis elegans
Highly calcium permeable nicotinic acetylcholine receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Proton-gated ion channel subunit pbo-6	G5EDF1 P48181 P48182 Q19351 Q23022 Q23355 Q27218 Q93149 Q93329 Q9N4M3 Q9N587	acr-12 acr-2 acr-3 acr-6 acr-8 lev-1 lev-7 lev-8 lgc-3 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors	AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor AcetylCholine Receptor Acetylcholine receptor subunit alpha-type unc-38 Acetylcholine receptor subunit alpha-type unc-63 Acetylcholine receptor subunit beta-type acr-2 Acetylcholine receptor subunit beta-type acr-3 Acetylcholine receptor subunit beta-type lev-1 Acetylcholine receptor subunit beta-type unc-29 Proton-gated ion channel subunit pbo-6	G5EDF1 P48181 P48182 Q19351 Q23022 Q23355 Q27218 Q93149 Q93329 Q9N4M3 Q9N587	acr-12 acr-2 acr-3 acr-6 acr-8 lev-1 lev-7 lev-8 lgc-3 pbo-6 unc-29 unc-38 unc-63	Caenorhabditis elegans
Fatty acyl-CoA biosynthesis	ATPase morc-1 Acetyl-CoA carboxylase Delta(9)-fatty-acid desaturase fat-5 Delta(9)-fatty-acid desaturase fat-6 Delta(9)-fatty-acid desaturase fat-7 Fatty acid synthase Long-chain-fatty-acid--CoA ligase Long-chain-fatty-acid--CoA ligase Palmitoyl-protein thioesterase 1 Probable ATP-citrate synthase	G5ED44 G5EGH6 G5EGN2 H2L0M0 P53585 P91871 Q18916 Q19878 Q20390 Q23243	acly-1 acs-20 acs-22 fasn-1 fat-5 fat-6 fat-7 morc-1 pod-2 ppt-1	Caenorhabditis elegans
Formation of the cornified envelope	Armadillo repeat-containing protein wrm-1 Beta-catenin-like protein hmp-2 Beta-catenin/armadillo-related protein 1 Cadherin-4 Cell junction protein VAB-9 Juxtamembrane domain-associated catenin	G5ED30 O44326 Q10953 Q18825 Q19319 Q9U308	bar-1 cdh-4 hmp-2 jac-1 pvl-1 spy-1 vab-9 wrm-1	Caenorhabditis elegans
Regulation of RUNX1 Expression and Activity	Core-binding factor subunit beta homolog bro-1 G1/S-specific cyclin-D RING-type E3 ubiquitin transferase RING-type domain-containing protein RING-type domain-containing protein Runt-related transcription factor rnt-1	G5ED20 G5EFQ5 H2L0K3 Q19818 Q95ZL9 Q9U2M5	bro-1 cyd-1 mab-2 nhl-2 nhl-3 rnt-1 run-1 tam-1	Caenorhabditis elegans
Regulation of PTEN localization	Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase daf-18 Polyubiquitin-A RING-type E3 ubiquitin transferase RING-type domain-containing protein RING-type domain-containing protein Ubiquitin carboxyl-terminal hydrolase 7 Ubiquitin-like protein 1-ribosomal protein eS31 fusion protein Ubiquitin-ribosomal protein eL40 fusion protein	G5ED20 G5EE01 H2L0K3 P0CG71 P37165 P49632 Q19818 Q7JKC3	daf-18 math-33 nhl-2 nhl-3 tam-1 ubia ubib ubl-1 ubq-1 ubq-2 usp-7	Caenorhabditis elegans
Calnexin/calreticulin cycle	Calnexin Calreticulin Protein disulfide-isomerase	G5ED07 P27798 P34652	cnx-1 crt-1 pdi-3	Caenorhabditis elegans
Glycogen synthesis	1,4-alpha-glucan branching enzyme Glycogen [starch] synthase Glycogenin-1 Nucleotide-diphospho-sugar transferase Protein phosphatase 1 regulatory subunit UTP--glucose-1-phosphate uridylyltransferase glycogenin glucosyltransferase phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)	G5ECZ5 H2KYQ5 O45819 Q21742 Q22137 Q966L7 Q9U2D9 Q9XUS5	CC8.2 CELE_R05F9.6 CELE_T04A8.7 CELE_T10B10.8 gsy-1 gyg-1 gyg-2 rml-1	Caenorhabditis elegans
Glycogen breakdown (glycogenolysis)	Alpha-1,4 glucan phosphorylase EF-hand domain-containing protein Glycogen debranching enzyme Glycogenin-1 Nucleotide-diphospho-sugar transferase Phosphorylase b kinase regulatory subunit Probable phosphorylase b kinase regulatory subunit alpha glycogenin glucosyltransferase phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) phosphorylase kinase	G5ECZ5 H2KYQ5 H2L0I6 O45819 O62334 P34335 Q18136 Q21742 Q9N3L4 Q9N5U1	C14B9.8 CELE_R05F9.6 CELE_T10B10.8 CELE_Y50D7A.3 CELE_Y67D8A.2 agl-1 cal-5 gyg-1 gyg-2 pygl-1	Caenorhabditis elegans	G58161NS
Sealing of the nuclear envelope (NE) by ESCRT-III	Charged multivesicular body protein 2a Charged multivesicular body protein 2b Charged multivesicular body protein 3 Charged multivesicular body protein 4b Charged multivesicular body protein 4b Charged multivesicular body protein 6 Charged multivesicular body protein 7 Coiled-coil and C2 domain-containing protein 1-like IST1 homolog Spastin homolog Vesicle-fusing ATPase	G5ECX8 O02208 Q18886 Q21959 Q22718 Q8MNV0 Q9BL60 Q9BL83 Q9GYK4 Q9U2F6 Q9U2M8	C01A2.4 CELE_R12C12.5 Y37H9A.3 chmp-7 istr-1 spas-1 vps-2 vps-20 vps-24 vps-32.1 vps-4	Caenorhabditis elegans
TWIK-releated acid-sensitive K+ channel (TASK)	Two pore potassium channel protein sup-9 Two pore potassium channel protein sup-9	G5ECW6 O17185	sup-9 twk-20	Caenorhabditis elegans
Metabolism of folate and pterines	10-formyltetrahydrofolate dehydrogenase Folate transporter 1 Folate-like transporter 2 Folate-like transporter 3 Methenyltetrahydrofolate cyclohydrolase Mitochondrial folate transporter/carrier Probable 5-formyltetrahydrofolate cyclo-ligase Probable methylenetetrahydrofolate reductase (NADPH) Proton-coupled folate transporter Putative dihydrofolate reductase Putative folylpolyglutamate synthase Serine hydroxymethyltransferase SoLute Carrier family Related SoLute Carrier family Related Solute carrier family 46 member 3	G5ECV9 H2KZC0 O45166 P50432 Q09509 Q17693 Q17766 Q20236 Q21084 Q21285 Q22931 Q93341 Q9UAZ6 Q9XWE6 Q9XWL3	F25B5.6 Y106G6E.4 alh-3 dao-3 dhfr-1 folt-1 folt-2 folt-3 gly-1 mel-32 mthf-1 slc-25A32 slc-25a32 slc-46A slc-46a slcr-46.1 slcr-46.2 slcr-46.3 tag-330	Caenorhabditis elegans

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