GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **252** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Sema3A PAK dependent Axon repulsion	Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta LIM domain kinase 1 Neuropilin-1a Plexin A3 Plexin-A1 Plexin-A2 Plexin-A4 Ras-related C3 botulinum toxin substrate 1 Semaphorin-3ab Tyrosine-protein kinase fynb non-specific serine/threonine protein kinase	A0A2R8QPJ6 A8IYK2 B0S5N4 F1RDG9 O57521 Q0PWB7 Q5RG12 Q6BEA0 Q6DG42 Q7ZSZ9 Q8QFX6 Q9W686	cb422 cb820 fynb hsp90a.2 hsp90a2 hsp90aa1.2 hsp90ab1 hsp90b hspc3 kinase limk1 limk1a np-1 nrp1 nrp1a pak2 pak2a plxna1 plxna1b plxna2 plxna3 plxna4 rac1 rac1a sema3ab semaz1b si:dz198m22.1 wu:fb71h01 wu:fd16e02 zgc:55823 zgc:55917 zgc:86934 zgc:91798	Danio rerio (zebrafish)
Keratinization	Desmocollin 2-like protein Desmoglein-2.1 Desmoplakin-A Junction plakoglobin a Keratin 18b Keratin 5 Keratin 93 Keratin 95 Keratin 97 Keratin, type II cytoskeletal 8 Plakophilin 3a Plakophilin-2 Uncharacterized protein LOC100009654 Uncharacterized protein LOC768289	A0A8M2BID5 A2RV44 B0BF33 F1Q8J9 F1QSQ0 F1QV31 H2EQR6 Q05AL9 Q1RLR3 Q6DG66 Q6DHU3 Q6NWF6 Q6PHE4 Q9PVF7	cb112 cb80 ckii dsc dsc2 dsc2l dsg2 dsg2.1 dsga dspa jup jupa krt18b krt2-8 krt5 krt8 krt93 krt94 krt95 krt97 krtt1c6 pkp2 pkp3 pkp3a sb:cb112 sb:cb481 wu:fa91c11 wu:fa91g11 wu:fa96h10 wu:fa97f09 wu:fb02h09 wu:fb58f07 wu:fj02d02 wu:fk69a12 wu:fk78b12 zfCKII zgc:136656 zgc:66015	Danio rerio (zebrafish)
Nicotinate metabolism	5'-nucleotidase Glutamine-dependent NAD(+) synthetase Mibp protein NAD(+) kinase Nicotinamide-nucleotide adenylyltransferase Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2	A5PLA8 E9QH56 Q568T8 Q6PC93 Q7SXU4 Q7ZW81	cb1024 id:ibd5068 im:7144541 mibp nadka nadsyn1 nmnat1 nmnat2 nt5e urk zgc:110083 zgc:110243 zgc:63784	Danio rerio (zebrafish)
Nectin/Necl trans heterodimerization	Cell adhesion molecule 1b isoform 1 Nectin 1b Nectin-3-like protein	B0F6R1 B0JYH6 Q58EG3	cadm1b nectin1b nectin3 pvrl1b pvrl3l sc:d0664	Danio rerio (zebrafish)
Crosslinking of collagen fibrils	Dorsal-ventral patterning tolloid-like protein 1 Lysyl oxidase homolog 2B Lysyl oxidase homolog 3B Lysyl oxidase homolog Metalloendopeptidase protein-lysine 6-oxidase	A1L1V4 B8A4W9 O57460 Q2ABP1 Q2PS19 Q6NYT8	bmp1a lox loxa loxl1 loxl2b loxl3b mfn si:ch211-238c15.1 tld tll1 tolloid zgc:77447	Danio rerio (zebrafish)
Apoptotic execution phase	Caspase 10, apoptosis-related cysteine peptidase Dynamin-1-like protein Endoplasmic reticulum transmembrane protein non-specific serine/threonine protein kinase	A3KP89 E7EXV8 Q7SXN5 Q7ZUJ4	bcap31 casp10 casp8l2 dnm1l si:bz30i22.4 si:rp71-30i22.4 stk24a zgc:163071 zgc:56389	Danio rerio (zebrafish)
Effects of PIP2 hydrolysis	Protein kinase C delta type Protein kinase C Protein kinase C Short transient receptor potential channel 3 Short transient receptor potential channel 6 isoform X1	B1H1I7 B8A467 F1RCY2 Q7ZUC5 U3N9R0	bZ1P14.9 fb09d10 fv43b11 prkcd prkcda prkceb prkcha si:rp71-1p14.9 trpc6 trpc6a trpc7b wu:fb09d10 wu:fv43b11 zgc:172124 zgc:56558	Danio rerio (zebrafish)
Lactose synthesis	Beta-1,4-galactosyltransferase Facilitated glucose transporter 1 lysozyme	C1KH59 Q285P3 Q90YS5	b4galt1l fc29a02 glut1 glut1a glut1b lys-C lyz slc2a1 slc2a1a wu:fc29a02 zgc:136734 zgc:154116	Danio rerio (zebrafish)	G58161NS G74621DY
Acyl chain remodelling of PG	Acyl-CoA Cytosolic phospholipase A2 Group XIIA secretory phospholipase A2 precursor Lysophosphatidylcholine acyltransferase 1 Phospholipase A2 cardiolipin synthase (CMP-forming) phospholipase A2	A3KNJ5 P50392 Q1LWG4 Q32PR6 Q4KMD5 Q6DHQ7 Q6NW82	aytl2 cpla2 crls1 fc21c12 fj66b10 lpcat1 lpgat1 pla2g10 pla2g12a pla2g3 pla2g4 pla2g4a si:dkey-30h14.2 wu:fc21c12 wu:fj66b10 zgc:112278 zgc:162119 zgc:85909	Danio rerio (zebrafish)
Acyl chain remodelling of PC	Cytosolic phospholipase A2 gamma-like Cytosolic phospholipase A2 Group XIIA secretory phospholipase A2 precursor Lysophosphatidylcholine acyltransferase 1 Lysophosphatidylcholine acyltransferase 2 Phospholipase A2 Phospholipase B-like Retinoic acid receptor responder 3-like lysoplasmalogenase lysoplasmalogenase phospholipase A2	A3KNJ5 B3DJ80 P50392 Q0P4C9 Q1LWG4 Q32PR6 Q502J0 Q5BLD1 Q5U3S0 Q6DHK9 Q6DHQ7	aytl1 aytl2 cpla2 im:7137034 im:7138859 lpcat1 lpcat2 pla2g10 pla2g12a pla2g3 pla2g4 pla2g4a plbd1 plbd1a rarres3l tmem86a tmem86b zgc:101699 zgc:113571 zgc:153124 zgc:162119	Danio rerio (zebrafish)
Asparagine N-linked glycosylation	Asialoglycoprotein receptor 1 Si Si	A4IG84 B3DFJ9 F8W3Q0	asgr1a cldc1 si:ch211-125e6.12 si:ch211-125e6.13 si:ch211-154o6.6 si:ch73-361h17.1 si:ch73-86n18.1	Danio rerio (zebrafish)
Dectin-2 family	Asialoglycoprotein receptor 1 CD247 antigen like precursor Immune-related lectin-like receptor 1 Immune-related lectin-like receptor-like Protein HEG Si Si Tyrosine-protein kinase fynb Uncharacterized protein LOC564690	A4IG84 A6Y958 A8WGQ6 B3DFJ9 F1RDG9 F8W3Q0 Q24K30 Q24K33 Q6R8J2	asgr1a cd247l cldc1 fynb heg illr1 illr4 illrL im:7156386 si:ch211-125e6.12 si:ch211-125e6.13 si:ch211-154o6.6 si:ch73-361h17.1 si:ch73-86n18.1 zgc:152681 zgc:174904	Danio rerio (zebrafish)
ARMS-mediated activation	Adapter molecule crk Kinase D-interacting substrate of 220 kDa B Nerve growth factor small monomeric GTPase	Q6DEM2 Q6IQP4 Q6YBR5 Q7T163	arms crk fb34h10 fc05a01 fi19g05 kidins220 kidins220b ngf ngfb rap1a rap1aa wu:fb34h10 wu:fc05a01 wu:fc54a04 wu:fc66g06 wu:fi19g05 zgc:100936 zgc:86676	Danio rerio (zebrafish)
Aggrephagy	ADP-ribosylation factor-like protein 13B Cystic fibrosis transmembrane conductance regulator Dynein light chain Dynein light intermediate chain Dynein, cytoplasmic 1, intermediate chain 2a E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase parkin Histone deacetylase 6 Parkinson disease protein 7 homolog Ubiquitin-conjugating enzyme E2 variant 1 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	E7F6H7 F8W4B7 Q1LUM9 Q1LX78 Q3B7F0 Q3B7P7 Q561U2 Q5BL99 Q5XJ36 Q7SXA3 Q803J2 Q8JHI3	arl13b arl2l1 cb741 cftr dj1 dlc-1 dncli2 dnl2 dnl2l dync1i2a dync1li1 dynll2a dynll2b fc73a07 hdac6 hm:zeh0386 ik:tdsubc_1f2 im:7136154 park2 park7 prkn rps27a si:ch211-123f21.1 si:dkey-63j1.8 tdsubc_1f2 uba52 ube2n ube2na ube2v1 wu:fa91f08 wu:fb11b03 wu:fc08b06 wu:fc73a07 xx:tdsubc_1f2 zgc:110812 zgc:112390 zgc:123326 zgc:123344 zgc:55726 zgc:66081 zgc:66168	Danio rerio (zebrafish)
Sema4D induced cell migration and growth-cone collapse	PDZ-RhoGEF Plexin b1b Ras-like protein Rnd1a Receptor protein-tyrosine kinase Rho-associated protein kinase Rho-related GTP-binding protein RhoA-C	F1Q7U0 Q49U75 Q52WX7 Q5EBY4 Q7T2E8 Q90Y37	arhgef11 erbb2 plxnb1b rhoac rnd1a rnd1b rnd1l rock2 rock2a rok2 wu:fk50c04 wu:fv70f10 zgc:153089 zgc:63601	Danio rerio (zebrafish)
Axonal growth stimulation	Nerve growth factor receptor b Nerve growth factor Rho GDP-dissociation inhibitor 1 Rho-related GTP-binding protein RhoA-C	E2DGP8 Q6YBR5 Q7T2E8 Q802W6	arhgdia ngf ngfb ngfrb ngfrl rhoac wu:fa96g11 zgc:55554 zgc:77681	Danio rerio (zebrafish)
Axonal growth inhibition (RHOA activation)	Leucine rich repeat and Ig domain containing 4b isoform X1 Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1-B Myelin-associated glycoprotein Nerve growth factor receptor b Reticulon Reticulon Rho GDP-dissociation inhibitor 1 Rho-related GTP-binding protein RhoA-C	A3KH16 E2DGP8 F1QSA4 Q4G5V0 Q4G5V7 Q66HV9 Q7T2E8 Q802W6	arhgdia fb64c01 im:7136397 lingo1 lingo1b lingo4b mag ngfrb ngfrl rhoac rtn1 rtn1a rtn4b rtn5 rtn6 siglec-4 wu:fa96g11 wu:fb64c01 wu:fc07e07 wu:fq24d12 zgc:113566 zgc:198379 zgc:55554 zgc:73298 zgc:77681 zgc:86778	Danio rerio (zebrafish)
VxPx cargo-targeting to cilium	ADP-ribosylation factor Polycystin-2 Rab-3A-interacting protein Rab11 family-interacting protein 3 Ras-related protein Rab-11A Ras-related protein Rab-8A Rhodopsin	A4FVK4 P35359 Q503R3 Q5U3E1 Q6DC20 Q6IVV8 Q7T005	arf4a pkd2 rab11a rab11fip3 rab3ip rab8 rab8a rho wu:fi15h09 zfo2 zgc:101030 zgc:103679 zgc:110270 zgc:162699 zgc:174360	Danio rerio (zebrafish)
Miscellaneous transport and binding events	Cystinosin precursor Leucine rich repeat containing 8 family, member A Leucine rich repeat containing 8 family, member D Leucine-rich repeat-containing 8 VRAC subunit Ab Magnesium transporter NIPA1 Magnesium transporter protein 1 NIPA-like domain containing 3 Progressive ankylosis protein homolog B Si	A2BF98 E7FB32 P58368 Q08BM6 Q4V8W3 Q503T0 Q5XJN7 Q6DHM4 Q7ZV50	ankh ankhb ctns lrrc8a lrrc8aa lrrc8ab lrrc8d lrrc8db magt1 nipa1 nipal3 npal3 si:zfos-323e3.4 wu:fb18g12 wu:fc12a05 wu:fi21b10 zgc:101743 zgc:110194 zgc:153223 zgc:92224	Danio rerio (zebrafish)
Tie2 Signaling	Angiopoietin-1 receptor Angiopoietin-1 Angiopoietin-2 GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Son of sevenless homolog phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A2RRV5 B0S6V7 B3DHG9 E7F251 F1QAD7 I6Z0F9 O73791 P79737 Q503B6 Q5RKN6 Q6PC73 Q90Z19	ang1 ang2-1 angpt1 angpt2a fb18e12 fj59e07 grb2 grb2a grb2b hrasb hrasl nras pik3ca pik3cb pik3r1 pik3r2 sos1 tek tie-2 tie2 wu:fb18e12 wu:fb34e06 wu:fb65b05 wu:fc76g06 wu:fj59e07 zgc:103549 zgc:110734 zgc:158274 zgc:73077	Danio rerio (zebrafish)
Digestion of dietary carbohydrate	Alpha-amylase chitinase chitinase	Q6NZZ8 Q6P006 Q6P5J0	amy2a amy3 chia.2 chia.3 chioIa chioIb wu:fb61c11 wu:fb64c06 wu:fd61a02 wu:fi13f01 zgc:55406 zgc:55941 zgc:66270 zgc:77877 zgc:77889 zgc:77912	Danio rerio (zebrafish)	G80384UV G96370VA
N-glycan trimming in the ER and Calnexin/Calreticulin cycle	Cytosolic endo-beta-N-acetylglucosaminidase E3 ubiquitin-protein ligase AMFR Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase Proteasome (Prosome, macropain) 26S subunit, ATPase, 1a Proteasome (Prosome, macropain) 26S subunit, ATPase, 1b Transitional endoplasmic reticulum ATPase UBX domain-containing protein 1 UV excision repair protein RAD23 Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	A1L251 F1QB30 Q32PS7 Q3B7P7 Q503I8 Q6IQ72 Q6NXA9 Q7SXA3 Q7ZU99 Q7ZWD1	amfra cdc48 engase hm:zeh0386 ik:tdsubc_1f2 ngly1 psmc1 psmc1a psmc1b rad23ab rps27a saks1 tdsubc_1f2 uba52 ubxn1 vcp wu:fa91f08 wu:fb05d04 wu:fj14c10 xx:tdsubc_1f2 zgc:123344 zgc:56516 zgc:66168 zgc:86923	Danio rerio (zebrafish)	G03934XO G25577BM G28233ME G51034LA G86419OL
Collagen chain trimerization	Collagen alpha-1(II) chain precursor Collagen alpha-1(XXVII) chain B Collagen alpha-1(XXVIII) chain isoform X1 (Fragment) Collagen alpha-2(I) chain precursor Collagen type XXVIII alpha 1 b Collagen, type I, alpha 1b precursor Solute carrier family 35 member C2	A0A060Q6E4 A0MSJ1 C0H5W1 F1R7R7 Q2LDA1 Q6IQX2 Q6PEI9	alpha2(I) alpha3(I) col1a1b col1a2 col1a3 col27a1 col27a1b col28a1 col28a1a col28a1b col28a1c col28a1d col2a1 col2a1a coll2a1 fb38c06 fc10c01 fj59a10 hm:zeh0348 hm:zehn2357 si:ch211-174d12.1 si:ch211-174d12.4 slc35c2 wu:fa95h05 wu:fa98d05 wu:fa99g10 wu:fb04c08 wu:fb11d06 wu:fb38c06 wu:fb99e07 wu:fc10c01 wu:fc49g11 wu:fd02a10 wu:fi09e02 wu:fj59a10 zehn2357 zgc:55285 zgc:77328	Danio rerio (zebrafish)
Digestion	Alkaline phosphatase Alkaline phosphatase alkaline phosphatase	H9GX67 Q4QRJ9 Q58EF1	alp3 alpi alpi.1 alpi.2 fb68b10 im:7149588 si:ch211-262h13.1 si:ch211-262h13.2 wu:fa95f04 wu:fb68b10 zgc:110409 zgc:110794	Danio rerio (zebrafish)
Signaling by LTK	ALK and LTK ligand 1 ALK and LTK ligand 2b Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Tyrosine-protein kinase receptor phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	B0S6V7 B3DHG9 E7F251 E7FAP8 F1QAD7 F1QVU0 F8W2C9	alkal1 alkal2b ltk pik3ca pik3cb pik3r1 pik3r2 wu:fb65b05	Danio rerio (zebrafish)

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