GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **176 - 200** of **252** in total

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Pathway Name ▼	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
FGFR4 ligand binding and activation	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 4 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q6PBT8 Q6SJP8 Q90413 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf6b fgf8 fgf8a fgfr4 id:ibd5158 wu:fb05c08 wu:fc89b01 zgc:194535	Danio rerio (zebrafish)
FGFR3c ligand binding and activation	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 3 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE2 Q6PBT8 Q6SJP8 Q9DFC9 Q9I8X3	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf5 fgf8 fgf8a fgfr3 id:ibd5158 wu:fb05c08 wu:fc89b01	Danio rerio (zebrafish)
FGFR3b ligand binding and activation	FGF18a Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 3 Fibroblast growth factor Putative fibroblast growth factor 1	O57341 Q38PL0 Q5TKR8 Q6PBT8 Q6SJP8 Q9I8X3	dob fgf-1 fgf-8 fgf1 fgf17 fgf17b fgf18 fgf18a fgf20a fgf8 fgf8a fgfr3 wu:fb05c08	Danio rerio (zebrafish)
FGFR2c ligand binding and activation	FGF18a Fgf23 Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DGE3 O57341 Q2HXK8 Q38PL0 Q5MK87 Q5TKR8 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q8JG38 Q9DFC9	dob fc89b01 fgf-1 fgf-8 fgf1 fgf16 fgf17 fgf17b fgf18 fgf18a fgf2 fgf20a fgf23 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr2 id:ibd5158 wu:fb05c08 wu:fc89b01 zgc:194535	Danio rerio (zebrafish)
FGFR2b ligand binding and activation	Fibroblast growth factor 3 Fibroblast growth factor receptor 2 Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Putative fibroblast growth factor 1	B3DHR9 P48802 Q1XG76 Q6PBT8 Q8AY90 Q8JG38	fgf-1 fgf-10 fgf-3 fgf1 fgf10 fgf10a fgf22 fgf3 fgf7 fgfr2 si:dkey-21e2.2 si:dkeyp-74c5.3 wu:fd11d03 zgc:109774	Danio rerio (zebrafish)
FGFR1c ligand binding and activation	Anosmin 1b Anosmin-1 Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GAIP c-terminus interacting protein 1 Putative fibroblast growth factor 1 Transforming growth factor beta receptor III	A0A0H3UK16 B3DGE3 O57341 Q1MT36 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6B337 Q6PBT8 Q6SJP8 Q90Z00 Q9DFC9 Q9IAR4	GIPC TIP-2 anos1a anos1b anosmin-1a anosmin-1b dob fc89b01 fgf-1 fgf-8 fgf1 fgf17 fgf17b fgf2 fgf20a fgf23 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a gipc1 id:ibd5158 kal1.1 kal1.2 kal1a kal1b rgs19ip1 si:ch73-18k18.1 tgfbr3 wu:fb05c08 wu:fc89b01 wu:fl91z45 zgc:194535	Danio rerio (zebrafish)
FGFR1c and Klotho ligand binding and activation	Fgf23 Fibroblast growth factor receptor 1-A Klotho	F1RC43 Q5MK87 Q90Z00	fgf23 fgfr1 fgfr1a kl	Danio rerio (zebrafish)
FGFR1b ligand binding and activation	Fibroblast growth factor 3 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor GAIP c-terminus interacting protein 1 Putative fibroblast growth factor 1 Transforming growth factor beta receptor III	A0A0H3UK16 B3DGE3 P48802 Q1XG76 Q6B337 Q6PBT8 Q8AY90 Q90Z00	GIPC TIP-2 fgf-1 fgf-10 fgf-3 fgf1 fgf10 fgf10a fgf2 fgf22 fgf3 fgfr1 fgfr1a gipc1 rgs19ip1 si:ch73-18k18.1 si:dkey-21e2.2 si:dkeyp-74c5.3 tgfbr3 wu:fd11d03 zgc:109774	Danio rerio (zebrafish)
Estrogen-dependent gene expression	Cbp/p300-interacting transactivator 1 Estrogen receptor Forkhead box A1 General transcription factor IIA, 1 Histone H2A.V Histone H2A Histone H2A Histone H2A Histone H2B 1/2 Histone H2B 3 Histone H2B Histone H2B Histone H2B Histone H3.2 Histone H3.3 Histone H4 Histone acetyltransferase KAT2B Histone acetyltransferase Histone-arginine methyltransferase CARM1 Nuclear receptor-interacting protein 1 Progesterone receptor Receptor protein-tyrosine kinase TATA-box-binding protein Transcription factor GATA-3 Transcription initiation factor IIA subunit 2 Transducin-like enhancer protein 3-B Uncharacterized protein LOC100126107 [histone H3]-trimethyl-L-lysine(9) demethylase	A3KPR4 A7E2M8 A7MCA8 B1AAP0 B3DJF8 B8LFF6 C9V3N7 F1QMY9 O13168 P57717 Q0Z946 Q1LUC3 Q1LUQ0 Q4QRF4 Q503H9 Q5BJA5 Q5XJK2 Q6DC04 Q6DHD0 Q6P0C9 Q6PC60 Q6PI20 Q71PD7 Q7SXL3 Q7ZTT0 Q7ZUK2 Q91428 R4GE15	LOC100150038 LOC100329358 LOC100331412 LOC100332229 LOC103908680 LOC108181627 LOC562770 LOC570661 LOC794549 carm1 cited1 erbb4 erbb4a esr esr1 fc15h02 fi05d05 fj36b10 fkd7 forkhead-7 foxa1 gata3 gb:dq017620 gro1 groucho1 gta3 gtf2a1 gtf2a2 h2af1al h2afvb h2afvl h2afx1 h2afza h2av h2ax1 h2az2a h2az2b h3-5 h3f3a h3f3b.1 h3f3c h3f3d hist2h2l im:6896397 jmjd2b kat2b kat5a kdm4b nr3a1 nrip1a pg pgr pr si:ch211-113a14.17 si:ch211-113a14.29 si:ch211-113a14.6 si:ch211-124a3.4 si:ch211-227n20.1 si:ch73-36p18.4 si:dkey-108k21.12 si:dkey-108k21.18 si:dkey-108k21.28 si:dkey-23a13.7 tbp tf2a tle3b wu:fc15h02 wu:fi05d05 wu:fj36b10 zgc:112234 zgc:113984 zgc:173585 zgc:173587 zgc:194998 zgc:55847 zgc:56685	Danio rerio (zebrafish)
Enzymatic degradation of dopamine by COMT	Catechol O-methyltransferase A Transmembrane O-methyltransferase homolog	A0A193KX02 F4ZGF2	comta mrc tomt	Danio rerio (zebrafish)
Enzymatic degradation of Dopamine by monoamine oxidase	Catechol O-methyltransferase A	F4ZGF2	comta	Danio rerio (zebrafish)
Energy dependent regulation of mTOR by LKB1-AMPK	5'-AMP-activated protein kinase subunit beta-1 5'-AMP-activated protein kinase subunit gamma-1 Acetyl-CoA carboxylase kinase GTP-binding protein Rheb Neutral amino acid transporter 9 Ragulator complex protein LAMTOR2 Ragulator complex protein LAMTOR3 Ragulator complex protein LAMTOR4 Ragulator complex protein LAMTOR5 Ras-related GTP-binding protein Ras-related GTP-binding protein Regulatory-associated protein of MTOR, complex 1 Serine/threonine-protein kinase TOR Target of rapamycin complex subunit lst8	A0A0R4IFI0 A5WUM0 E7FA90 Q06RG6 Q08BA4 Q0P3X8 Q502N9 Q503S6 Q6DEG4 Q6DHM2 Q6PC18 Q6PCS7 Q7ZUI2 Q803V5	RRAGB cb116 frap1 gbl im:7154392 lamtor2 lamtor3 lamtor4 lamtor5 lst8 mapksp1 mlst8 mtor prkaa1 prkab1a prkag1 rheb rptor rraga rragc rragca sb:cb130 si:dkey-176g4.2 slc38a9 tor wu:fa94c10 wu:fa94d09 wu:fc22h08 wu:fc68h09 wu:fd12h04 zgc:111971 zgc:56499 zgc:63896 zgc:73144 zgc:92228	Danio rerio (zebrafish)
Elevation of cytosolic Ca2+ levels	P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor P2X purinoceptor Short transient receptor potential channel 3 Short transient receptor potential channel 6 isoform X1	B0R182 F1RCY2 Q7SZL9 Q7SZM0 Q7SZM1 Q7SZM2 Q9I8N8 U3N9R0	P2X.514 P2X3 bZ1P14.9 fb99b08 p2rx1 p2rx2 p2rx3 p2rx3a p2rx5 p2rx7 p2rx8 p2x3 p2x5 p2xr1 p2xr2 p2xr514 p2xr7 si:rp71-1p14.9 trpc6 trpc6a trpc7b wu:fb99b08 zP2X3 zfP2X3	Danio rerio (zebrafish)
Electric Transmission Across Gap Junctions	Gap junction protein Gap junction protein Pannexin-1 Pannexin	B0FL75 B1P2E8 Q7ZUN0 Q8JFD6	PANX connexin35 cx35 cx35b cx52.7 gja10a gja9 gjd2b panx1 panx1a panx2 si:ch211-192n14.2 zgc:194445 zgc:194451 zgc:55631	Danio rerio (zebrafish)
Effects of PIP2 hydrolysis	Protein kinase C delta type Protein kinase C Protein kinase C Short transient receptor potential channel 3 Short transient receptor potential channel 6 isoform X1	B1H1I7 B8A467 F1RCY2 Q7ZUC5 U3N9R0	bZ1P14.9 fb09d10 fv43b11 prkcd prkcda prkceb prkcha si:rp71-1p14.9 trpc6 trpc6a trpc7b wu:fb09d10 wu:fv43b11 zgc:172124 zgc:56558	Danio rerio (zebrafish)
ESR-mediated signaling	Esr2a protein Estrogen receptor Heat shock protein HSP 90-alpha Heat shock protein HSP 90-beta Prostaglandin E synthase 3	O57521 P57717 Q5RG12 Q7SZQ8 Q7ZU32	ER[b]2 ER[b]a Tebp cPGES-1 cb820 erbeta2 esr esr1 esr2a hsp90a.2 hsp90a2 hsp90aa1.2 hsp90ab1 hsp90b hspc3 nr3a1 ptges3 ptges3a wu:fb98d06 zfER-beta2 zfER[b]2 zgc:65804 zgc:77131	Danio rerio (zebrafish)
EPHB-mediated forward signaling	Actin, cytoplasmic 1 Actin, cytoplasmic 2 Actin-related protein 2-A Actin-related protein 2-B Actin-related protein 2/3 complex subunit 3 Actin-related protein 2/3 complex subunit 4 Actin-related protein 2/3 complex subunit 5 Actin-related protein 2/3 complex subunit Actin-related protein 2/3 complex subunit Actin-related protein 3 Arp2/3 complex 34 kDa subunit Cell division control protein 42 homolog GTPase HRas Neural Wiskott-Aldrich syndrome protein RAS p21 protein activator (GTPase-activating protein) 1b Rho-associated protein kinase Rho-related GTP-binding protein RhoA-C Syndecan	A2RUY4 E7F372 Q503B6 Q52WY2 Q56A35 Q66I66 Q6NZZ2 Q6P2T5 Q6PUQ3 Q6ZM62 Q7SXW6 Q7T2E8 Q7T372 Q7ZUQ0 Q7ZVF9 Q7ZVI7 Q7ZWH4 Q90Y37	ARPC1A actba actbb actr2 actr2a actr2b actr3 arp2a arp2b arpc1a arpc1b arpc2 arpc3 arpc4 arpc4l arpc5b bact bactin1 bactin2 bactzf cb440 cb871 cdc42 cdc42a fa07b12 fj15h02 fj62g06 fk84a07 hrasb hrasl rasa1b rhoac rock2 rock2a rok2 sdc2 wasla wu:fa07b12 wu:fa22f07 wu:fb07d08 wu:fb63b05 wu:fj08e12 wu:fj15h02 wu:fj62g06 wu:fk84a07 wu:fk93e03 zgc:101093 zgc:103676 zgc:110734 zgc:158395 zgc:63918 zgc:64056 zgc:77769 zgc:77932 zgc:86828	Danio rerio (zebrafish)
EPHA-mediated growth cone collapse	Proto-oncogene tyrosine-protein kinase Src Rho-related GTP-binding protein RhoA-C Tyrosine-protein kinase fynb Tyrosine-protein kinase yes	A1A5H8 F1RDG9 Q1JPZ3 Q7T2E8	fynb rhoac src yes yes1	Danio rerio (zebrafish)
EPH-Ephrin signaling	Ephrin B3 Ephrin type-A receptor 3 Ephrin type-A receptor 4a (Fragment) Ephrin type-B receptor 4a Ephrin-A1 Ephrin-A2 Ephrin-A3 Ephrin-A5b Ephrin-B1 Ephrin-B2b receptor protein-tyrosine kinase receptor protein-tyrosine kinase receptor protein-tyrosine kinase	O13146 O13148 O73875 O93431 P79727 P79728 Q5VSJ4 Q6NZS1 Q90YC5 Q90Z31 Q90Z32 Q90Z33 Q90ZN9	D160 EphA3 RTK2 al1 efna1 efna1b efna2 efna3 efna3b efna5 efna5b efnb1 efnb2b efnb3 efnb3b ek1 ek2 epha2 epha2a epha3 epha4 epha4a epha4b epha7 ephb4a ephrin-A3 eplg6 eplg7 fc10d03 fc51g03 hm:zeh0344 id:ibd2782 id:ibd5049 id:ibd5152 lerk6 lerk7 rtk2 rtk5 rtk6 si:dkey-23k6.1 wu:fc10d03 wu:fc51g03 zeh0344 zek1 zek2 zgc:100772 zgc:111938	Danio rerio (zebrafish)
EGR2 and SOX10-mediated initiation of Schwann cell myelination	Adhesion G-protein coupled receptor G6	C6KFA3	adgrg6 gpr126	Danio rerio (zebrafish)
Downstream signaling of activated FGFR1	Fgf23 Fibroblast growth factor 17 Fibroblast growth factor 3 Fibroblast growth factor 8 Fibroblast growth factor receptor 1-A Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibroblast growth factor Fibronectin leucine-rich transmembrane protein 1b Fibronectin leucine-rich transmembrane protein 2 Klotho Putative fibroblast growth factor 1	B3DGE3 F1QF54 F1RC43 O57341 P48802 Q1XG76 Q38PL0 Q5MK87 Q5TLE1 Q5TLE2 Q6PBT8 Q6SJP8 Q8AY90 Q90Z00 Q9DFC9 X1WEV4	dob fc89b01 fgf-1 fgf-10 fgf-3 fgf-8 fgf1 fgf10 fgf10a fgf17 fgf17b fgf2 fgf20a fgf22 fgf23 fgf3 fgf4 fgf5 fgf6b fgf8 fgf8a fgfr1 fgfr1a flrt1b flrt2 id:ibd5158 kl si:dkey-21e2.2 si:dkey-87k14.1 si:dkeyp-74c5.3 wu:fb05c08 wu:fc89b01 wu:fd11d03 zgc:109774 zgc:194535	Danio rerio (zebrafish)
Downstream signal transduction	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma Adapter molecule crk Crk-like protein Cytoplasmic protein Cytoplasmic protein GTPase HRas GTPase NRas Growth factor receptor-bound protein 2 Growth factor receptor-bound protein 2a Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Platelet-derived growth factor receptor alpha Platelet-derived growth factor subunit A Platelet-derived growth factor subunit B Proto-oncogene tyrosine-protein kinase Src Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Signal transducer and activator of transcription Son of sevenless homolog phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A2R8Q0D8 A2RRV5 B0S6V7 B3DGV1 B3DHG9 E7F251 E7F6M0 F1QAD7 O93598 P79737 Q08CD2 Q1JPZ3 Q4V9A1 Q503B6 Q5RKN6 Q68SP2 Q68SP3 Q6DEM2 Q6PC73 Q6PH06 Q804J6 Q9DE49	Stat5 crk crkl fb18e12 fb34h10 fc05a01 fd20h08 fi19g05 fj46f04 fj59e07 grb2 grb2a grb2b hrasb hrasl im:7147817 nck1b nck2b nras pdgfab pdgfbb pdgfra pik3ca pik3cb pik3r1 pik3r2 plcg1 sb:eu508 sb:eu615 si:ch211-147g19.3 sos1 src stat1 stat1a stat5 stat5.1 stat5.2 stat5a stat5b stat6 stat7 wu:fa55g05 wu:fb18e12 wu:fb34e06 wu:fb34h10 wu:fb65b05 wu:fc05a01 wu:fc32c12 wu:fc54a04 wu:fd20h08 wu:fi19g05 wu:fj46f04 wu:fj57a05 wu:fj59e07 wu:fj60e01 wu:fj66g07 zgc:100936 zgc:103549 zgc:110734 zgc:153249 zgc:158274 zgc:63469 zgc:73077 zgc:92024	Danio rerio (zebrafish)
Disassembly of the destruction complex and recruitment of AXIN to the membrane	Axin-1 Caveolin Dishevelled, dsh homolog 2 (Drosophila) Frizzled 8a protein Frizzled 8b protein Frizzled class receptor 5 Frizzled homolog 2 Frizzled-1 Low density lipoprotein receptor-related protein 5 Low-density lipoprotein receptor-related protein Protein Wnt-1 Protein Wnt-8a Protein Wnt-8b Protein Wnt	B3DIG4 B3DJ49 B5L5I6 F1QTJ4 P24257 P51028 P51029 P57094 Q6IYD9 Q6YLH9 Q803Q5 Q90YL7 Q9PWK6 Q9YI00	CAV1 LRP6 ZG06 Zfz8b Zwnt[a] axin axin1 cav1 cb383 dvl2 fz10 fz2 fz3 fz5 fz6 fz8 fz8a fz8b fz8c fzA fzc fzd1 fzd2 fzd5 fzd8a fzd8b fzd8c ik:tdsubc_1e1 int-1 lrp5 lrp6 sb:eu471 wnt-1 wnt-8 wnt-8b wnt1 wnt3 wnt3 l wnt3a wnt3l wnt8 wnt8a wnt8b wnt[a] wu:fb70g09 wu:fc05d12 wu:fc07c04 wu:fd02c05 wu:fo71e09 wu:fp54a02 xx:tdsubc_1e1 zfz2 zfzA zg02 zg03 zg05 zg08 zg10 zgc:194774 zgc:55372	Danio rerio (zebrafish)
Digestion of dietary carbohydrate	Alpha-amylase chitinase chitinase	Q6NZZ8 Q6P006 Q6P5J0	amy2a amy3 chia.2 chia.3 chioIa chioIb wu:fb61c11 wu:fb64c06 wu:fd61a02 wu:fi13f01 zgc:55406 zgc:55941 zgc:66270 zgc:77877 zgc:77889 zgc:77912	Danio rerio (zebrafish)	G80384UV G96370VA
Digestion	Alkaline phosphatase Alkaline phosphatase alkaline phosphatase	H9GX67 Q4QRJ9 Q58EF1	alp3 alpi alpi.1 alpi.2 fb68b10 im:7149588 si:ch211-262h13.1 si:ch211-262h13.2 wu:fa95f04 wu:fb68b10 zgc:110409 zgc:110794	Danio rerio (zebrafish)

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