GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **51 - 75** of **128** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
HS-GAG degradation	Alpha-N-acetylglucosaminidase Beta-galactosidase 1 Beta-xylosidase-like protein	Q54DW5 Q54GE1 Q54J53	DDB_G0288289 glb1 naglu	Dictyostelium discoideum	G01550VL G09546QO
Regulation of TP53 Activity through Phosphorylation	Casein kinase II subunit alpha Casein kinase II subunit beta FACT complex subunit SPT16 FACT complex subunit SSRP1 Probable serine/threonine-protein kinase DDB_G0286481 Probable serine/threonine-protein kinase atr1 Probable serine/threonine-protein kinase dyrk2	Q02720 Q54BC9 Q54ER4 Q54G78 Q54LR6 Q54PF1 Q54S43	DDB_G0286481 atr1 casK csnk2b dyrk2 spt16 ssrp ssrp1	Dictyostelium discoideum
Metal ion SLC transporters	Copper transport protein Metal transporter nramp1 homolog Probable zinc transporter protein DDB_G0282067	Q54N27 Q54T06 Q869V1	DDB_G0282067 DDB_G0285545 nramp nramp1 slc11a1	Dictyostelium discoideum
Condensation of Prometaphase Chromosomes	Casein kinase II subunit alpha Casein kinase II subunit beta Condensin complex subunit 2 Condensin-2 complex subunit D3 Nuclear condensin complex subunit 3 C-terminal domain-containing protein Probable serine/threonine-protein kinase DDB_G0286481 Structural maintenance of chromosomes protein 2	Q02720 Q54B17 Q54DR4 Q54LR6 Q54PF1 Q54PK4 Q54TZ8	DDB_G0281419 DDB_G0286481 DDB_G0292066 DDB_G0293984 casK csnk2b smc2	Dictyostelium discoideum
Cyclin D associated events in G1	Cullin-2 Cyclin-dependent kinases regulatory subunit EF-hand domain-containing protein Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Protein phosphatase 2A scaffold subunit Retinoblastoma-like protein A SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b Serine/threonine-protein phosphatase 2A catalytic subunit A Serine/threonine-protein phosphatase 2A regulatory subunit phr2AB Transcription factor E2F/dimerisation partner family protein Transcription factor E2F/dimerisation partner family protein Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein	B0G102 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P52285 Q54CI0 Q54FX2 Q54Q23 Q54Q99 Q54QR9 Q54W95 Q557E4 Q7KWP1 Q9XZE5 Q9XZJ3	DDB_G0279813 E2F PP2A PP2Ac Rb cks1 cul2 culB fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 pho2a phr2aB pppA pppD rblA rcdB skp1A skp1B tfdp2 ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116 veg124	Dictyostelium discoideum
Post-translational modification: synthesis of GPI-anchored proteins	CN hydrolase domain-containing protein Peptidase M14 family protein Phosphatidylinositol-glycan-specific phospholipase D Xaa-Pro aminopeptidase 1	Q54G06 Q54I77 Q54WG1 Q86AV9	DDB_G0279675 DDB_G0288963 pldG xpnpep1 xpnpepl xpnpepl1	Dictyostelium discoideum
Acyl chain remodelling of PI	Membrane bound O-acyl transferase family protein Phospholipase B-like protein D	Q54PS7 Q54XX2	DDB_G0278541 plbD	Dictyostelium discoideum
Acyl chain remodelling of PE	Membrane bound O-acyl transferase family protein Patatin family protein Phospholipase B-like protein D	Q54PS7 Q54QX6 Q54XX2	DDB_G0278541 DDB_G0283551 plbD	Dictyostelium discoideum
Acyl chain remodelling of PC	Lysoplasmalogenase homolog Membrane bound O-acyl transferase family protein Patatin family protein Phospholipase B-like protein D	Q54PS7 Q54QX6 Q54XX2 Q86H31	DDB_G0278541 DDB_G0283551 plbD tmem86	Dictyostelium discoideum
Regulation of HSF1-mediated heat shock response	14-3-3-like protein Extracellular signal-regulated kinase 1 Glycogen synthase kinase-3 Heat shock 70 kDa protein, mitochondrial Heat shock 70-related protein 5 Heat shock cognate 70 kDa protein 1 Heat shock cognate 70 kDa protein 2 Heat shock cognate 70 kDa protein 3 Heat shock cognate 70 kDa protein 4 Heat shock factor-type DNA-binding domain-containing protein Heat shock protein 88 Luminal-binding protein 2 Myb domain-containing protein Protein OPI10 homolog	P36415 P42525 P51136 P54632 Q54BD8 Q54BE0 Q54MR6 Q54TH5 Q54UC1 Q54YL9 Q557E0 Q6TMK3 Q8I0H7 Q8T869	DDB_G0278179 DDB_G0281165 DDB_G0281747 DDB_G0285709 DDB_G0293674 DDB_G0293678 bip2 erk1 erkA fttB gsk3 gskA hsc70 hsp70 hspB hspE-1 hspE-2 hspH mhsp70	Dictyostelium discoideum
Lactose synthesis	Calmodulin-binding protein Sugar transporter family protein	Q54CM5 Q54Z55	DDB_G0277773 symA	Dictyostelium discoideum	G58161NS
Regulation of insulin secretion	Calmodulin-binding protein Sugar transporter family protein	Q54CM5 Q54Z55	DDB_G0277773 symA	Dictyostelium discoideum	G58161NS
Intestinal hexose absorption	Calmodulin-binding protein Sugar transporter family protein	Q54CM5 Q54Z55	DDB_G0277773 symA	Dictyostelium discoideum	G58161NS G93924TT
Receptor Mediated Mitophagy	Autophagy protein 5 Autophagy-related protein 8-like protein DDB_G0290491 Autophagy-related protein 8 Casein kinase II subunit alpha Casein kinase II subunit beta Probable serine/threonine-protein kinase DDB_G0286481 Serine/threonine-protein kinase atg1 Transmembrane protein Ubiquitin-like protein atg12	Q02720 Q54G11 Q54GT9 Q54LR6 Q54PF1 Q75K07 Q86CR6 Q86CR8 Q86CS2	DDB_G0277699 DDB_G0286481 DDB_G0290491 apg1 apg12 apg5 apg8 atg1 atg12 atg5 atg8 casK csnk2b	Dictyostelium discoideum
Transport of bile salts and organic acids, metal ions and amine compounds	CTL-like protein DDB_G0288717 Choline transporter-like protein 2 Multi antimicrobial extrusion family protein Multi antimicrobial extrusion family protein Urea transporter	Q54DM2 Q54I48 Q54IJ2 Q54YM8 Q86AP4	DDB_G0277263 DDB_G0278161 DDB_G0288717 DDB_G0292132 ctl2 slc44a2	Dictyostelium discoideum
Choline catabolism	CTL-like protein DDB_G0288717 Choline dehydrogenase Choline transporter-like protein 2 Putative aldehyde dehydrogenase family 7 member A1 homolog	B0G160 P83401 Q54I48 Q54IJ2	DDB_G0276821 DDB_G0288717 chdh ctl2 slc44a2	Dictyostelium discoideum
Cellular hexose transport	Calmodulin-binding protein Major facilitator superfamily (MFS) profile domain-containing protein Sugar transporter SWEET1 Sugar transporter family protein Sugar transporter family protein Uncharacterized protein	Q54CM5 Q54JW5 Q54M69 Q54UC8 Q54Z55 Q7KWK4	DDB_G0276801 DDB_G0277773 DDB_G0281155 DDB_G0286151 slc50a1 symA	Dictyostelium discoideum	G58161NS
Reactions specific to the complex N-glycan synthesis pathway	Alpha-L-fucosidase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase alpha-L-fucosidase	P10901 Q54BB7 Q54L56 Q54P60 Q54PH9 Q54PJ9 Q54PK0 Q54PK3 Q54RA6 Q551C1 Q55FA8 Q86J24	DDB_G0276661 alfA fut1 fut10 fut11 fut2 fut3 fut4 fut5 fut6 fut7 fut9	Dictyostelium discoideum	G82576YO
Synthesis of glycosylphosphatidylinositol (GPI)	GPI ethanolamine phosphate transferase 1 GPI mannosyltransferase 1 GPI mannosyltransferase 2 Mannosyltransferase Mannosyltransferase Phosphatidylinositol glycan, class F Phosphatidylinositol glycan, class X Phosphatidylinositol-glycan biosynthesis class W protein Probable N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase Transmembrane protein	Q1ZXB4 Q54C64 Q54IA4 Q54MC0 Q54PB0 Q54PM5 Q54QP2 Q54UQ5 Q54WY9 Q551Y7	DDB_G0276251 DDB_G0280891 pigB pigF pigN pigX pigl pigm pigw smp3	Dictyostelium discoideum
Lysosomal oligosaccharide catabolism	Alpha-mannosidase B Alpha-mannosidase C Alpha-mannosidase D Alpha-mannosidase E Alpha-mannosidase F Alpha-mannosidase G Lysosomal alpha-mannosidase beta-mannosidase	P34098 Q1ZXI8 Q54K67 Q54KN4 Q54YC4 Q54YF7 Q552S3 Q55ER0	DDB_G0275917 manA manB manC manD manE manF manG	Dictyostelium discoideum	G00027MO G25577BM G28233ME G70323CJ G90333CG
Synthesis of IP3 and IP4 in the cytosol	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase Calmodulin-like protein Calmodulin Inositol 5-phosphatase 4 Inositol 5-phosphatase Inositol-tetrakisphosphate 1-kinase Kinase LIM-domain containing phosphatase Myosin-ID light chain Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase cnrN Phospholipase D Y Phospholipase D Z Uncharacterized protein phosphoinositide 5-phosphatase	O00897 P02599 Q02158 Q54CH3 Q54D97 Q54JL7 Q54K50 Q54MG8 Q54SA1 Q54TI0 Q54W40 Q553B4 Q55D87 Q7Z2B8 Q8I7P3 Q8T9S7	DDB_G0275865 DDB_G0281737 DDB_G0285967 DDB_G0292920 Dd5P1 Dd5P3 Dd5P4 ITPK1 calA calB camA cnrN mlcD pipA plc pld3 pldY pldZ pteN ptenA	Dictyostelium discoideum
TP53 Regulates Metabolic Genes	14-3-3-like protein 5'-AMP-activated protein kinase subunit gamma 5'-AMP-activated serine/threonine-protein kinase catalytic subunit alpha Association with the SNF1 complex (ASC) domain-containing protein GTP-binding protein Rheb homolog Glucose-6-phosphate 1-dehydrogenase Glucose-6-phosphate isomerase Glutathione reductase Peroxiredoxin-4 Probable serine/threonine-protein kinase DDB_G0288795 Probable serine/threonine-protein kinase MARK-B Protein LST8 homolog Protein raptor homolog Putative thioredoxin-4 RAC family serine/threonine-protein kinase homolog Ragulator complex protein LAMTOR3 homolog Ragulator complex protein LAMTOR4 homolog Ragulator complex protein LAMTOR5 homolog RapGAP/RanGAP domain-containing protein Ras-related GTP-binding protein A Ras-related GTP-binding protein Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase tor Sestrin homolog Thioredoxin domain-containing protein Thioredoxin-3 Uncharacterized protein DDB_G0292160	P29447 P54632 P54644 Q1ZXA8 Q1ZXE0 Q54D08 Q54DY3 Q54F59 Q54IF2 Q54IK1 Q54MV2 Q54N76 Q54PK6 Q54QW5 Q54UG7 Q54VB2 Q54WU6 Q54YF2 Q550Q4 Q555L5 Q557D2 Q55BR7 Q5V9E9 Q86C65 Q86J23 Q8T137 Q8T277	DDB_G0274833 DDB_G0279427 DDB_G0280527 DDB_G0283567 DDB_G0288795 DDB_G0291948 DDB_G0292160 akt ampka dagA fttB g6pd-1 g6pd-2 g6pi gpi gsr lst8 mapbpip mrkB pgi pkbA prdx4 prdx5 prkaa prkab prkag ragA ragC raptor rheb snfA tor trx3 trx4 trxC trxD zwf	Dictyostelium discoideum
ROS and RNS production in phagocytes	Metal transporter nramp1 homolog NADPH--cytochrome P450 reductase V-ATPase proteolipid subunit C-like domain-containing protein V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit d Vacuolar proton translocating ATPase 100 kDa subunit	O00780 P54641 P54642 P54647 P54648 Q54E04 Q54Z13 Q55AH5 Q55CT1 Q76NU1 Q869V1 Q86A77 Q86AS7 Q8MML6	DDB_G0274141 atp6v1d atp6v1g dvacB nramp nramp1 redB slc11a1 vatA vatB vatC vatD-1 vatD-2 vatE vatF vatH vatM vatP vatg	Dictyostelium discoideum
PI3K/AKT Signaling	Probable serine/threonine-protein kinase DDB_G0288795 Probable serine/threonine-protein kinase pdkA Protein LST8 homolog Protein pianissimo A RAC family serine/threonine-protein kinase homolog Ras-interacting protein RIP3 Serine/threonine-protein kinase tor Thioesterase domain-containing protein	O77203 P54644 Q54D08 Q54IF2 Q54TW2 Q556W3 Q86C65 Q9Y0C9	DDB_G0273293 DDB_G0288795 DG1117 akt amiA dagA lst8 pdkA pia piaA pkbA rip3 ripA tor	Dictyostelium discoideum
Detoxification of Reactive Oxygen Species	1-Cys peroxiredoxin Catalase-A Cytochrome c Extracellular superoxide dismutase [Cu-Zn] 2 Extracellular superoxide dismutase [Cu-Zn] 3 Glutathione S-transferase domain-containing protein DDB_G0273153/DDB_G0273923 Glutathione reductase Peroxiredoxin-4 Probable copper chaperone for superoxide dismutase Probable superoxide dismutase [Cu-Zn] 6 Putative glutathione S-transferase alpha-1 Putative glutathione S-transferase alpha-2 Putative glutathione S-transferase alpha-3 Putative glutathione S-transferase alpha-4 Putative glutathione S-transferase alpha-5 Putative thioredoxin-4 Superoxide dismutase [Cu-Zn] 4 Superoxide dismutase [Cu-Zn] 5 Superoxide dismutase [Mn], mitochondrial Superoxide-generating NADPH oxidase heavy chain subunit A Superoxide-generating NADPH oxidase heavy chain subunit B Superoxide-generating NADPH oxidase heavy chain subunit C Thioredoxin domain-containing protein Thioredoxin domain-containing protein Thioredoxin-3	O77229 P29447 Q1ZXE0 Q54F44 Q54F73 Q54G70 Q54N76 Q54NX3 Q54QV7 Q54RN1 Q54RQ1 Q54SE2 Q54TU5 Q54TW8 Q54VI4 Q555L5 Q556G3 Q556P3 Q55BJ9 Q55FF3 Q869N1 Q86AU1 Q86GL4 Q8T137 Q9XYS3	DDB_G0273153 DDB_G0282517 DDB_G0284939 cat catA ccs ccsA cytC gsr gsta1 gsta2-1 gsta2-2 gsta3 gsta4 gsta5 noxA noxB noxC prdx4 prdx5 sod2 sodB sodC sodD sodE sodF trx3 trx4 trxC trxD	Dictyostelium discoideum

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