GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **76 - 100** of **128** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol ▼	Organism	GlyTouCan ID
Orc1 removal from chromatin	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Cullin-2 Origin recognition complex subunit 1 Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RING-box protein 1 SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P52285 Q1ZXD3 Q27562 Q27563 Q54BC6 Q54BC8 Q54CI0 Q54DB2 Q54DM7 Q54HW1 Q54JM5 Q54K33 Q54NQ0 Q54PJ1 Q54PN7 Q54QR2 Q54RM2 Q54S82 Q54UB5 Q54UJ0 Q54WI8 Q54XM7 Q552Y8 Q553E0 Q556Q0 Q557E4 Q559F4 Q55BV5 Q55C75 Q55D66 Q55DY7 Q55G04 Q55GJ6 Q86IJ1 Q86JA1 Q967U1 Q9XZJ3	DDB_G0272951 M4 cul2 culB dapA dpr1 fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 orc1 orcA prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbx1 skp1A skp1B sks1 tbp2 tbpB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116	Dictyostelium discoideum
ABC-family proteins mediated transport	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 ABC transporter A family member 2 ABC transporter A family member 3 ABC transporter A family member 4 ABC transporter A family member 5 ABC transporter A family member 6 ABC transporter B family member 2 ABC transporter B family member 3 ABC transporter B family member 6 ABC transporter B family member 7 ABC transporter C family member 10 ABC transporter C family member 12 ABC transporter C family member 13 ABC transporter C family member 14 ABC transporter C family member 15 ABC transporter C family member 1 ABC transporter C family member 2 ABC transporter C family member 3 ABC transporter C family member 5 ABC transporter C family member 6 ABC transporter C family member 7 ABC transporter C family member 8 ABC transporter C family member 9 ABC transporter F family member 4 Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3 Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 Serine protease/ABC transporter B family protein tagA Serine protease/ABC transporter B family protein tagB Serine protease/ABC transporter B family protein tagC Serine protease/ABC transporter B family protein tagD Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein	P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P54683 Q1ZXD3 Q23868 Q27562 Q27563 Q54BC6 Q54BC8 Q54BT3 Q54BT5 Q54CI0 Q54DB2 Q54DM7 Q54EK2 Q54HW1 Q54JM5 Q54JR2 Q54K24 Q54LE6 Q54NL1 Q54NQ0 Q54P13 Q54PJ1 Q54PN7 Q54QR2 Q54RU1 Q54S82 Q54T27 Q54U44 Q54UB5 Q54UJ0 Q54V86 Q54VC1 Q54VJ0 Q54WI8 Q54XD8 Q54XM7 Q552Y8 Q553E0 Q555Z5 Q556Q0 Q559F4 Q55BV5 Q55C75 Q55D66 Q55DA7 Q55DY7 Q55G04 Q55GJ6 Q869N9 Q86IJ1 Q86JA1 Q8ST87 Q8T6B4 Q8T6H3 Q8T6H8 Q8T6J1 Q8T6J2 Q8T6J5 Q8T9W1 Q8T9W4 Q967U1 Q9GTN7	DDB_G0272951 M4 abcA2 abcA3 abcA4 abcA5 abcA6 abcB2 abcB3 abcB6 abcB7 abcC1 abcC10 abcC12 abcC13 abcC14 abcC15 abcC2 abcC3 abcC5 abcC6 abcC7 abcC8 abcC9 abcF4 dapA dpr1 eif2G eif2a eif2b eif2s1 eif2s2 eif2s3 prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 sks1 tagA tagB tagC tagD tbp2 tbpB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO veg116	Dictyostelium discoideum
Glycosphingolipid catabolism	Alpha-galactosidase Beta-galactosidase 1 Beta-hexosaminidase subunit A1 Beta-hexosaminidase subunit A2 Beta-hexosaminidase subunit B1 Beta-hexosaminidase subunit B2 Glucosylceramidase Neutral ceramidase A Probable alpha-galactosidase Saposin A Sphingomyelin phosphodiesterase A Sphingomyelin phosphodiesterase B Sphingomyelinase DDB_G0288017 Type I phosphodiesterase/nucleotide pyrophosphatase family protein Uncharacterized protein DDB_G0272682 beta-N-acetylhexosaminidase	P13723 Q1ZXD9 Q54BK2 Q54C16 Q54D71 Q54EG4 Q54GE1 Q54K55 Q54K56 Q54MJ8 Q54MU9 Q54Q68 Q54SC9 Q55B10 Q55C09 Q86IG2	DDB_G0272682 DDB_G0285897 DDB_G0288017 DDB_G0291524 DDB_G0292446 dcd dcd2A glb1 hexa1 hexa2 hexb1 hexb2 melA nagA nagE rsc25 sapA sgmA sgmB	Dictyostelium discoideum	G09546QO G27025MB G58161NS
Sphingolipid catabolism	Aldehyde dehydrogenase family 3 comG PA-phosphatase related-family protein DDB_G0271516 PA-phosphatase related-family protein DDB_G0275547 PA-phosphatase related-family protein DDB_G0284367 Probable sphingosine-1-phosphate phosphatase Putative alkaline ceramidase dcd3A Sphingosine-1-phosphate lyase	Q54DG1 Q54PR7 Q54RV9 Q55A00 Q6TMJ1 Q86AF0 Q8MXL9	DDB_G0271516 DDB_G0275547 DDB_G0284367 comG dcd3A sglA sppA	Dictyostelium discoideum
Role of phospholipids in phagocytosis	PA-phosphatase related-family protein DDB_G0271516 PA-phosphatase related-family protein DDB_G0275547 PA-phosphatase related-family protein DDB_G0284367 Phospholipase D A Phospholipase D B Phospholipase D C Phospholipase D Y Phospholipase D Z Probable serine/threonine-protein kinase DDB_G0288795 RAC family serine/threonine-protein kinase homolog phospholipase D	P54644 Q54IF2 Q54K50 Q54PR7 Q54Q49 Q54SA1 Q54UK0 Q54WR4 Q54Z25 Q86AF0 Q8MXL9	DDB_G0271516 DDB_G0275547 DDB_G0284155 DDB_G0284367 DDB_G0288795 akt dagA pkbA pld1 pld3 pldA pldB pldC pldY pldZ	Dictyostelium discoideum
Toll Like Receptor 4 (TLR4) Cascade	UPF0522 protein A UPF0522 protein B UPF0522 protein C	Q54JE7 Q54JE8 Q55BA2	DDB_G0271242 DDB_G0288095 DDB_G0288097	Dictyostelium discoideum
Regulation of TLR by endogenous ligand	Non-histone chromosomal protein 6 homolog UPF0522 protein A UPF0522 protein B UPF0522 protein C	Q54JE7 Q54JE8 Q55BA2 Q55C24	DDB_G0271242 DDB_G0288095 DDB_G0288097 nhp6	Dictyostelium discoideum
Antimicrobial peptides	Transglycosylase SLT domain-containing protein UPF0522 protein C	Q54XV8 Q55BA2	DDB_G0271242 DDB_G0278563	Dictyostelium discoideum	G49108TO
G alpha (i) signalling events	Guanine nucleotide-binding protein alpha-9 subunit Guanine nucleotide-binding protein subunit beta Metabotropic glutamate receptor-like protein E Metabotropic glutamate receptor-like protein P Metabotropic glutamate receptor-like protein Q RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein	P36408 Q54ET0 Q54F54 Q54K09 Q54LD1 Q54M81 Q54R41 Q54S99 Q54XJ6 Q556I3 Q55E55	DDB_G0270858 DDB_G0273033 DDB_G0278897 DDB_G0282583 DDB_G0286173 DDB_G0286817 GluPR gpa9 gpaI gpbA grlE grlP grlQ	Dictyostelium discoideum
G alpha (q) signalling events	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase G-protein alpha subunit family protein Guanine nucleotide-binding protein alpha-1 subunit Guanine nucleotide-binding protein alpha-12 subunit Guanine nucleotide-binding protein alpha-2 subunit Guanine nucleotide-binding protein alpha-3 subunit Guanine nucleotide-binding protein alpha-4 subunit Guanine nucleotide-binding protein alpha-5 subunit Guanine nucleotide-binding protein alpha-6 subunit Guanine nucleotide-binding protein alpha-7 subunit Guanine nucleotide-binding protein alpha-8 subunit Guanine nucleotide-binding protein-like alpha-10 subunit Guanine nucleotide-binding protein-like alpha-11 subunit RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein RGS domain-containing protein	P16051 P16894 P34042 P34043 P34044 P34045 P34046 Q02158 Q54KV6 Q54LD1 Q54M81 Q54S99 Q54UG5 Q54VG1 Q54XJ6 Q556I3 Q55E55 Q55EP5 Q8T130	DDB_G0270858 DDB_G0273033 DDB_G0278897 DDB_G0282583 DDB_G0286173 DDB_G0286817 Ga3 gbqA gpa10 gpa11 gpa12 gpaA gpaB gpaC gpaD gpaE gpaF gpaG gpaH gpaJ gpaK gpaL pipA plc	Dictyostelium discoideum
Hyaluronan biosynthesis and export	Protein DDB_G0287365 Transmembrane protein	Q54KF6 Q55D62	DDB_G0270636 DDB_G0287365	Dictyostelium discoideum	G35674CY
LDL clearance	AP-1 complex subunit beta AP-2 complex subunit alpha-2 AP-2 complex subunit mu AP-2 complex subunit sigma Carboxylic ester hydrolase Clathrin heavy chain Clathrin light chain Countin-3 FYVE-type domain-containing protein Kynurenine formamidase MD-2-related lipid-recognition domain-containing protein MD-2-related lipid-recognition domain-containing protein Putative phosphatidylglycerol/phosphatidylinositol transfer protein 1 Putative phosphatidylglycerol/phosphatidylinositol transfer protein 2 Putative phosphatidylglycerol/phosphatidylinositol transfer protein 3 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0278295 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282107 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0282179 Putative phosphatidylglycerol/phosphatidylinositol transfer protein DDB_G0285639 SSD domain-containing protein	P25870 P54672 Q54ET7 Q54H39 Q54KP7 Q54MV4 Q54QI3 Q54R44 Q54SW1 Q54SW2 Q54SZ8 Q54SZ9 Q54TL9 Q54X82 Q54YD2 Q551C5 Q55BL4 Q86HV8 Q86KI1 Q8MN58	DDB_G0270454 DDB_G0276657 DDB_G0278295 DDB_G0281675 DDB_G0282107 DDB_G0282109 DDB_G0282177 DDB_G0282179 DDB_G0283413 DDB_G0283819 DDB_G0285639 DDB_G0287185 DDB_G0291344 ap1b1 ap2a1-1 ap2a1-2 ap2s1 apm1 apm2 apmA chcA clc clcA ctnC	Dictyostelium discoideum
Linoleic acid (LA) metabolism	ABC transporter D family member 3 Carrier domain-containing protein Elongation of fatty acids protein Elongation of fatty acids protein Elongation of fatty acids protein Fatty acid elongase A Fatty acid elongase sre1 Fatty acyl-CoA synthetase A Fatty acyl-CoA synthetase B Putative fatty acid elongase DDB_G0272012 Putative fatty acid elongase DDB_G0274669	C7FZW5 Q1ZXQ4 Q54CJ4 Q54JK0 Q54TC9 Q54W20 Q555E8 Q55BY4 Q55DR6 Q7KWQ5 Q86JM5	DDB_G0270312 DDB_G0271066 DDB_G0272012 DDB_G0274669 DDB_G0277569 DDB_G0288001 abcD3 eloA fcsA fcsB sre1	Dictyostelium discoideum
alpha-linolenic acid (ALA) metabolism	ABC transporter D family member 3 Carrier domain-containing protein Elongation of fatty acids protein Elongation of fatty acids protein Elongation of fatty acids protein Fatty acid elongase A Fatty acid elongase sre1 Fatty acyl-CoA synthetase A Fatty acyl-CoA synthetase B Peroxisomal acyl-coenzyme A oxidase 1 Probable enoyl-CoA hydratase 2 Putative fatty acid elongase DDB_G0272012 Putative fatty acid elongase DDB_G0274669 acetyl-CoA C-acyltransferase	C7FZW5 Q1ZXQ4 Q54CJ4 Q54GQ6 Q54JK0 Q54TC9 Q54W20 Q54XZ0 Q555E8 Q55BY4 Q55DR6 Q7KWQ5 Q86IY4 Q86JM5	DDB_G0270312 DDB_G0271066 DDB_G0272012 DDB_G0274339 DDB_G0274669 DDB_G0277569 DDB_G0288001 abcD3 acox1 eloA fcsA fcsB mfe2 mfeB sre1	Dictyostelium discoideum
Lewis blood group biosynthesis	Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase Fucosyltransferase WD40 repeat-containing protein	Q54BB7 Q54L56 Q54P60 Q54PH9 Q54PJ9 Q54PK0 Q54PK3 Q54RA6 Q55C63 Q55FA8 Q86J24	DDB_G0270208 fut1 fut10 fut11 fut2 fut3 fut4 fut5 fut6 fut7 fut9	Dictyostelium discoideum	G81971FM G90387AM G98173LG
Synthesis of very long-chain fatty acyl-CoAs	AMP-dependent synthetase/ligase domain-containing protein Acyl-CoA synthetase family member 3, mitochondrial Carrier domain-containing protein Elongation of fatty acids protein Elongation of fatty acids protein Elongation of fatty acids protein Fatty acid elongase A Fatty acid elongase sre1 Fatty acyl-CoA synthetase A Fatty acyl-CoA synthetase B Putative fatty acid elongase DDB_G0272012 Putative fatty acid elongase DDB_G0274669 Uncharacterized protein Very-long-chain enoyl-CoA reductase very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase	C7FZW5 Q1ZXQ4 Q54CJ4 Q54HD3 Q54JK0 Q54TC9 Q54Y54 Q54YR9 Q555E8 Q55BY4 Q55C17 Q55CD5 Q55DR6 Q7KWQ5 Q869Y3 Q86JM5	DDB_G0270106 DDB_G0270312 DDB_G0271066 DDB_G0272012 DDB_G0274669 DDB_G0275049 DDB_G0277569 DDB_G0278113 DDB_G0278683 DDB_G0288001 DDB_G0289539 eloA fcsA fcsB gpsn2 sre1	Dictyostelium discoideum
KEAP1-NFE2L2 pathway	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Autophagy-related protein 8-like protein DDB_G0290491 Autophagy-related protein 8 Cell division cycle protein 48 Cullin-3 Nuclear protein localization protein 4 homolog Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RING finger domain and kelch repeat-containing protein DDB_G0271372 RING-box protein 1 Sestrin homolog UBX domain-containing protein 7 homolog Ubiquitin fusion degradation protein 1 homolog Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein ZZ-type zinc finger-containing protein	P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P90532 Q1ZXD3 Q27562 Q27563 Q54BC6 Q54BC8 Q54CI0 Q54DB2 Q54DM7 Q54G11 Q54GD3 Q54HW1 Q54JM5 Q54K33 Q54NQ0 Q54NZ5 Q54PJ1 Q54PN7 Q54QR2 Q54S82 Q54UB5 Q54UJ0 Q54WI8 Q54WU6 Q54XM7 Q552Y8 Q553E0 Q556Q0 Q559F4 Q55BF8 Q55BK0 Q55BU7 Q55BV5 Q55C75 Q55CE3 Q55D66 Q55DY7 Q55G04 Q55GJ6 Q86CR8 Q86IJ1 Q86JA1 Q967U1	DDB_G0270098 DDB_G0271372 DDB_G0272951 DDB_G0279427 DDB_G0290491 M4 apg8 atg8 cdcD cul3 culC dapA dpr1 npl4 nploc4 prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbx1 sks1 tbp2 tbpB ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO ubxd7 ufd1 veg116	Dictyostelium discoideum
Interleukin-4 and Interleukin-13 signaling	C2H2-type domain-containing protein Endoplasmin homolog Signal transducer and activator of transcription A Signal transducer and activator of transcription B Signal transducer and activator of transcription C Signal transducer and activator of transcription Uncharacterized protein Uncharacterized protein	O00910 Q54BD4 Q54GL9 Q54WB7 Q55CI5 Q70GP4 Q86I20 Q9NKX1	DDB_G0270046 DDB_G0279767 DDB_G0290073 dstA dstB dstC dstD grp94 stat5 statA statB statC	Dictyostelium discoideum
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 3beta-hydroxysteroid dehydrogenase Cycloartenol synthase Delta(14)-sterol reductase Diphosphomevalonate decarboxylase Farnesyl diphosphate synthase Geranylgeranyl pyrophosphate synthase Hydroxymethylglutaryl-CoA synthase B Isopentenyl-diphosphate Delta-isomerase Mevalonate kinase Phosphatidic acid phosphatase type 2/haloperoxidase domain-containing protein Probable acetyl-CoA acetyltransferase Probable lanosterol 14-alpha demethylase Protein arv1 homolog Putative methylsterol monooxygenase DDB_G0269788 Squalene monooxygenase Squalene synthase	P34135 Q1ZXH9 Q54BK1 Q54BK7 Q54DR1 Q54GD9 Q54PP1 Q54TU9 Q54UH9 Q54YQ9 Q55D54 Q55D85 Q86AD9 Q86AG7 Q86HL5 Q9NH02 Q9NH03	DDB_G0269788 DDB_G0271544 DDB_G0281069 DDB_G0281487 Dipi arv1 cas1 cyp51 erg24 fdfT fps ggps1 hgsB hmgA idi ipi mvd mvk sqle	Dictyostelium discoideum
Synthesis of bile acids and bile salts	Oxysterol-binding protein 11 Oxysterol-binding protein 4 Oxysterol-binding protein 6 Oxysterol-binding protein 8 Putative methylsterol monooxygenase DDB_G0269788 Putative methylsterol monooxygenase DDB_G0270946 Sterol desaturase family protein	Q54ID7 Q54QP6 Q54WK0 Q55D52 Q55D54 Q86HV4 Q86KG4	DDB_G0269788 DDB_G0270946 DDB_G0279611 osbD osbF osbH osbK	Dictyostelium discoideum
Neddylation	26S proteasome non-ATPase regulatory subunit 10 26S proteasome non-ATPase regulatory subunit 11 26S proteasome non-ATPase regulatory subunit 12 26S proteasome non-ATPase regulatory subunit 13 26S proteasome non-ATPase regulatory subunit 14 26S proteasome non-ATPase regulatory subunit 1 26S proteasome non-ATPase regulatory subunit 2 26S proteasome non-ATPase regulatory subunit 3 26S proteasome non-ATPase regulatory subunit 4 26S proteasome non-ATPase regulatory subunit 6 26S proteasome non-ATPase regulatory subunit 7 26S proteasome regulatory subunit 10B 26S proteasome regulatory subunit 4 homolog 26S proteasome regulatory subunit 6A homolog 26S proteasome regulatory subunit 6B homolog 26S proteasome regulatory subunit 7 Ankyrin repeat-containing protein Ankyrin repeat-containing protein B30.2/SPRY domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB domain-containing protein BTB/POZ domain-containing protein COMM domain-containing protein 10 COMM domain-containing protein 1 COMM domain-containing protein 2 COMM domain-containing protein 3 COMM domain-containing protein 4 COMM domain-containing protein 5 COMM domain-containing protein 6 COMM domain-containing protein 7 COMM domain-containing protein 8 COP9 signalosome complex subunit 1 COP9 signalosome complex subunit 2 COP9 signalosome complex subunit 3 COP9 signalosome complex subunit 4 COP9 signalosome complex subunit 5 COP9 signalosome complex subunit 6 COP9 signalosome complex subunit 7 COP9 signalosome complex subunit 8 Calponin-homology (CH) domain-containing protein Cell division cycle protein 48 Coiled-coil domain-containing protein 22 homolog Cullin-1 Cullin-2 Cullin-3 Cullin-4 Cullin-5 Cullin-associated NEDD8-dissociated protein 1 Cyclin-like F-box containing protein Cyclin-like F-box containing protein DCN1-like protein 1 DCN1-like protein 2 DDB1- and CUL4-associated factor 13 DDB1- and CUL4-associated factor 7 homolog DET1- and DDB1-associated protein 1 domain-containing protein DNA damage-binding protein 1 Defective in cullin neddylation protein Elongin-C F-box domain-containing protein Homeobox protein Wariai Kelch repeat-containing protein Myotrophin homolog NEDD8-activating enzyme E1 catalytic subunit NEDD8-activating enzyme E1 regulatory subunit NEDD8-conjugating enzyme Ubc12 NEDD8 Nuclear protein localization protein 4 homolog Polyubiquitin-F Polyubiquitin-G Polyubiquitin-H Polyubiquitin-I Polyubiquitin-J Probable 26S proteasome non-ATPase regulatory subunit 8 Probable 26S proteasome non-ATPase regulatory subunit 9 Probable histone-binding protein rbbD Probable ubiquitin carboxyl-terminal hydrolase Proteasome activator 28 Proteasome activator complex subunit 4 Proteasome inhibitor PI31 subunit Proteasome subunit alpha type-1 Proteasome subunit alpha type-2 Proteasome subunit alpha type-3 Proteasome subunit alpha type-4 Proteasome subunit alpha type-5 Proteasome subunit alpha type-6 Proteasome subunit alpha type-7 Proteasome subunit beta type-2 Proteasome subunit beta type-3 Proteasome subunit beta type-4 Proteasome subunit beta type-5 Proteasome subunit beta type-6 Proteasome subunit beta type-7 RING finger domain and kelch repeat-containing protein DDB_G0271372 RING-box protein 1 RING-type domain-containing protein Retinoblastoma-binding-like protein E SCF ubiquitin ligase complex protein SKP1a SCF ubiquitin ligase complex protein SKP1b Trishanku UBR-type domain-containing protein UBX domain-containing protein 7 homolog Ubiquitin fusion degradation protein 1 homolog Ubiquitin-like domain-containing protein Ubiquitin-ribosomal protein eL40 fusion protein Ubiquitin-ribosomal protein eS31 fusion protein Uncharacterized protein Uncharacterized protein Uncharacterized protein Uncharacterized protein WD repeat-containing protein 5 homolog WD40 repeat-containing protein WD40 repeat-containing protein WD40 repeat-containing protein WD40 repeat-containing protein	B0G147 B0M0P5 O60999 P02889 P0CG78 P0CG79 P0CG80 P0CG81 P0CG88 P14794 P14797 P34119 P34120 P34123 P52285 P90532 Q1ZXD3 Q27562 Q27563 Q54B82 Q54BC6 Q54BC8 Q54C92 Q54CI0 Q54CS2 Q54CU8 Q54D84 Q54DB2 Q54DF3 Q54DL2 Q54DM7 Q54DR0 Q54DZ4 Q54E28 Q54E53 Q54F46 Q54GD3 Q54GP1 Q54HL6 Q54HW1 Q54I00 Q54IQ0 Q54IY4 Q54J43 Q54JM3 Q54JM5 Q54K33 Q54KL5 Q54LM6 Q54LV9 Q54MA5 Q54MH6 Q54MP2 Q54NQ0 Q54NZ5 Q54P14 Q54PF3 Q54PJ1 Q54PN7 Q54Q05 Q54Q43 Q54QG9 Q54QK4 Q54QR2 Q54QX3 Q54S82 Q54SD4 Q54T48 Q54TI6 Q54UB5 Q54UJ0 Q54UQ3 Q54V70 Q54WI8 Q54XA6 Q54XF7 Q54XM7 Q54XV3 Q54Y77 Q550I8 Q550W4 Q551N8 Q552R1 Q552Y8 Q553E0 Q554G3 Q556Q0 Q557E4 Q559F4 Q55BD5 Q55BF8 Q55BK0 Q55BU7 Q55BV5 Q55C56 Q55C75 Q55D66 Q55DE3 Q55DY7 Q55FM5 Q55G04 Q55GJ6 Q75JX5 Q75K24 Q7KWL3 Q86I14 Q86IJ1 Q86IW8 Q86JA1 Q86JC1 Q86JM4 Q86K42 Q86KD1 Q967U1 Q9XZJ3	DDB_G0269686 DDB_G0270220 DDB_G0271372 DDB_G0272016 DDB_G0272218 DDB_G0272666 DDB_G0272951 DDB_G0277011 DDB_G0277249 DDB_G0278671 DDB_G0279093 DDB_G0280581 DDB_G0280895 DDB_G0284157 DDB_G0284369 DDB_G0285813 DDB_G0286387 DDB_G0286565 DDB_G0288453 DDB_G0288597 DDB_G0289099 DDB_G0290025 DDB_G0291902 DDB_G0292144 DDB_G0292302 M4 appbp1 cand1 cdcD cnrM commd1 commd10 commd2 commd3 commd4 commd5 commd6 commd7 commd8 csn1 csn2 csn3 csn4 csn5 csn6 csn7 csn8 cul1 cul2 cul3 cul4 cul5 culA culB culC culD culE dapA ddb1 dpr1 ercc8 fp21A fp21B fpa1 fpa1A fpa1B fpa2 fpaA fpaB-1 fpaB-2 hbx1 mtpn nae1 nedd8 npl4 nploc4 prdD prdE prtC prtD psmA1 psmA2 psmA3 psmA4 psmA5 psmA6 psmA7 psmB2 psmB3 psmB4-1 psmB4-2 psmB5 psmB6 psmB7 psmC1 psmC2 psmC3 psmC4 psmC6 psmD1 psmD10 psmD11 psmD12 psmD13 psmD14 psmD2 psmD3 psmD4 psmD6 psmD7 psmD8-1 psmD8-2 psmD9 psmE3 psmE4 psmF1 rbbD rbbE rbx1 repE skp1A skp1B sks1 tbp2 tbpB tceb1 triA uba3 ube1c ube2m ubqB ubqC ubqF ubqG ubqH ubqI ubqJ ubqO ubxd7 uch1 uchl ufd1 veg116 warA wdr23 wdr5 wdr68 wdsof1 wri	Dictyostelium discoideum
Amino acids regulate mTORC1	DEP domain-containing protein DDB_G0279099 Folliculin GATOR2 complex protein MIOS GATOR2 complex protein WDR24 GTP-binding protein Rheb homolog Kaptin NPR2 family protein Protein LST8 homolog Protein SEC13 homolog Protein raptor homolog Ragulator complex protein LAMTOR3 homolog Ragulator complex protein LAMTOR4 homolog Ragulator complex protein LAMTOR5 homolog Ras-related GTP-binding protein A Ras-related GTP-binding protein Roadblock/LAMTOR2 domain-containing protein Serine/threonine-protein kinase tor Sestrin homolog UDENN FNIP1/2-type domain-containing protein UPF0171 family protein Uncharacterized protein DDB_G0292160 Uncharacterized protein Uncharacterized protein Uncharacterized protein V-ATPase proteolipid subunit C-like domain-containing protein V-type proton ATPase catalytic subunit A V-type proton ATPase proteolipid subunit V-type proton ATPase subunit B V-type proton ATPase subunit C V-type proton ATPase subunit D V-type proton ATPase subunit E V-type proton ATPase subunit F V-type proton ATPase subunit G V-type proton ATPase subunit H V-type proton ATPase subunit d VWFA domain-containing protein Vacuolar proton translocating ATPase 100 kDa subunit WD repeat-containing protein DDB_G0292056	O00780 P54641 P54642 P54647 P54648 Q1ZXA8 Q54D08 Q54DS4 Q54DS8 Q54DY3 Q54E04 Q54F59 Q54HT9 Q54IK1 Q54JS5 Q54NW3 Q54PK6 Q54QW5 Q54UF2 Q54UN5 Q54WU6 Q54XA2 Q54Y15 Q54Z13 Q550Q4 Q551B5 Q55AH5 Q55BD9 Q55BR7 Q55DE8 Q76NU1 Q86A77 Q86AS7 Q86C65 Q86IH5 Q86J23 Q86K39 Q8MML6	DDB_G0269680 DDB_G0271288 DDB_G0272696 DDB_G0274141 DDB_G0274833 DDB_G0277257 DDB_G0278475 DDB_G0279099 DDB_G0279427 DDB_G0280947 DDB_G0281111 DDB_G0283567 DDB_G0284957 DDB_G0289243 DDB_G0291948 DDB_G0292056 DDB_G0292160 atp6v1d atp6v1g dvacB lst8 mapbpip mios ragA ragC raptor rheb sec13 tor vatA vatB vatC vatD-1 vatD-2 vatE vatF vatH vatM vatP vatg wdr24	Dictyostelium discoideum
GDP-fucose biosynthesis	Fucokinase Fucose-1-phosphate guanylyltransferase GDP-L-fucose synthase GDP-fucose transporter 1 GDP-mannose 4,6 dehydratase	Q1ZXF7 Q54NH4 Q550W6 Q55C77 Q55DE9	DDB_G0269678 fpgt fuct1 ger gmd slc35c1	Dictyostelium discoideum	G85196CF
Synthesis of PA	Counting factor 60 DDHD domain-containing protein DDHD domain-containing protein DDHD domain-containing protein DDHD domain-containing protein Mitochondrial cardiolipin hydrolase Phospholipase D A Phospholipase D B Phospholipase D C Phospholipid/glycerol acyltransferase domain-containing protein Phospholipid/glycerol acyltransferase domain-containing protein Phospholipid/glycerol acyltransferase domain-containing protein Phospholipid/glycerol acyltransferase domain-containing protein Probable acid phosphatase DDB_G0284753 Probable acid phosphatase DDB_G0284755 Probable glycerol-3-phosphate dehydrogenase, mitochondrial phospholipase D	Q54EA5 Q54EU4 Q54IT8 Q54P71 Q54P72 Q54PR9 Q54Q49 Q54QC1 Q54TK6 Q54UK0 Q54WR4 Q54Z25 Q554U0 Q55CZ2 Q55DN9 Q55DP0 Q86KP6	DDB_G0269584 DDB_G0269848 DDB_G0270566 DDB_G0274969 DDB_G0276935 DDB_G0281695 DDB_G0283951 DDB_G0284155 DDB_G0284753 DDB_G0284755 DDB_G0288523 DDB_G0291332 DDB_G0291694 cf60 pld1 pldA pldB pldC	Dictyostelium discoideum
Fatty acyl-CoA biosynthesis	3-oxoacyl-[acyl-carrier-protein] reductase Acetyl-CoA carboxylase Delta 9 fatty acid desaturase Delta 9 fatty acid desaturase MaoC-like domain-containing protein Palmitoyl-protein thioesterase 1 Palmitoyl-protein thioesterase 2 Probable ATP-citrate synthase Probable polyketide synthase 16 Probable polyketide synthase 17 Probable polyketide synthase 1	Q54IE5 Q54IE9 Q54J08 Q54N35 Q54T75 Q54YA0 Q556T4 Q55E72 Q55E82 Q869W9 Q869X2	DDB_G0269356 DDB_G0273105 DDB_G0281965 DDB_G0288801 accA acly pks1 pks16 pks17 ppt1 ppt2 stlA	Dictyostelium discoideum

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