GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **526 - 550** of **1070** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Uptake of dietary cobalamins into enterocytes	Cobalamin binding intrinsic factor Cubilin Protein amnionless	D3ZFK9 O70244 P17267	Amn Cblif Cubn Gif Ifcr	Rattus norvegicus (Norway rat)
Signaling by MST1	Macrophage stimulating 1 Serine peptidase inhibitor, Kunitz type 1 Serine peptidase inhibitor, Kunitz type, 2 Serine protease hepsin receptor protein-tyrosine kinase	A0A8I6A5T6 F7FMS0 G3V8S0 Q05511 Q4V8Q2	Hpn Mst1 Mst1r Spint1 Spint2	Rattus norvegicus (Norway rat)
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase	Anaphase promoting complex subunit 1 Anaphase promoting complex subunit 7 Anaphase-promoting complex subunit 15 Anaphase-promoting complex subunit 16 Anaphase-promoting complex subunit 2 Anaphase-promoting complex subunit 4 Anaphase-promoting complex subunit 5 Anaphase-promoting complex subunit CDC26 Cell division cycle 14A Cell division cycle 16 Cell division cycle 23 Cell division cycle protein 20 homolog Cell division cycle protein 27 homolog E2 ubiquitin-conjugating enzyme Fizzy and cell division cycle 20 related 1 Ubiquitin-conjugating enzyme E2 C Ubiquitin-conjugating enzyme E2 D1 Ubiquitin-conjugating enzyme E2 S	A0A8I6A4J8 A0A8I6AE10 A0A8I6ANL9 A0A8I6B415 A1L1K3 B1WCA1 B5DFI8 D3ZDK2 D3ZDN9 D3ZIT4 D3ZQX4 D3ZUB7 D3ZUW6 F1M3L4 F7EWF8 Q4V8A2 Q62623 Q6YDN7	Anapc1 Anapc15 Anapc16 Anapc2 Anapc4 Anapc5 Anapc7 Cdc14a Cdc16 Cdc20 Cdc23 Cdc26 Cdc27 Fzr1 LOC100366017 Ube2c Ube2d1 Ube2e1 Ube2s	Rattus norvegicus (Norway rat)
ABO blood group biosynthesis	Galactoside alpha-(1,2)-fucosyltransferase 1 Galactoside alpha-(1,2)-fucosyltransferase 2 Histo-blood group ABO system transferase 2 Histo-blood group ABO system transferase 2	D4A7T1 Q10980 Q10984 Q8CFC4	Abo2 Fta Ftb Fut1 Fut2 Sec1	Rattus norvegicus (Norway rat)
RUNX3 regulates NOTCH signaling	Histone acetyltransferase Histone acetyltransferase Histone lysine acetyltransferase CREBBP Mastermind-like transcriptional coactivator 1 Mastermind-like transcriptional coactivator 2 Mastermind-like transcriptional coactivator 3 Recombination signal binding protein for immunoglobulin kappa J region Runt-related transcription factor SNW domain-containing protein 1 histone acetyltransferase	A0A0G2K7T0 A0A8I5Y222 A0A8I5ZP60 A0A8I5ZUF4 A0A8I6ABZ3 A0A8I6G641 D4A930 D4ACX5 F1M3B2 Q6JHU9	Cbp Crebbp Ep300 Kat2a Kat2b Maml1 Maml2 Maml3 Rbpj Runx3 Snw1	Rattus norvegicus (Norway rat)
Translation initiation complex formation	40S ribosomal protein S12 40S ribosomal protein S26 40S ribosomal protein S7 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic translation initiation factor 1A Eukaryotic translation initiation factor 2 subunit 1 Eukaryotic translation initiation factor 2 subunit 2 Eukaryotic translation initiation factor 2 subunit 3, X-linked Eukaryotic translation initiation factor 3 subunit A Eukaryotic translation initiation factor 3 subunit B Eukaryotic translation initiation factor 3 subunit C Eukaryotic translation initiation factor 3 subunit D Eukaryotic translation initiation factor 3 subunit E Eukaryotic translation initiation factor 3 subunit F Eukaryotic translation initiation factor 3 subunit G Eukaryotic translation initiation factor 3 subunit H Eukaryotic translation initiation factor 3 subunit I Eukaryotic translation initiation factor 3 subunit J Eukaryotic translation initiation factor 3 subunit K Eukaryotic translation initiation factor 3 subunit L Eukaryotic translation initiation factor 3 subunit M Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4E Eukaryotic translation initiation factor 4H Polyadenylate-binding protein 1 Small ribosomal subunit protein eS10 Small ribosomal subunit protein eS17 Small ribosomal subunit protein eS19 Small ribosomal subunit protein eS1 Small ribosomal subunit protein eS21 Small ribosomal subunit protein eS24 Small ribosomal subunit protein eS25 Small ribosomal subunit protein eS26 Small ribosomal subunit protein eS27-like Small ribosomal subunit protein eS27 Small ribosomal subunit protein eS28 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS4 Small ribosomal subunit protein eS6 Small ribosomal subunit protein eS7 Small ribosomal subunit protein eS8 Small ribosomal subunit protein uS10 Small ribosomal subunit protein uS11 Small ribosomal subunit protein uS12 Small ribosomal subunit protein uS13 Small ribosomal subunit protein uS14 Small ribosomal subunit protein uS15 Small ribosomal subunit protein uS17 Small ribosomal subunit protein uS19 Small ribosomal subunit protein uS2 Small ribosomal subunit protein uS3 Small ribosomal subunit protein uS4 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS5 Small ribosomal subunit protein uS7 Small ribosomal subunit protein uS8 Small ribosomal subunit protein uS9 Ubiquitin-like protein FUBI Ubiquitin-ribosomal protein eS31 fusion protein	A0A8I5ZLD0 A0A8I5ZX29 A0A8I6AIB7 A0A8I6G5P0 A0A8I6GEL5 A0JPM9 B0BNA7 B5DFC8 D3Z8D7 D3ZAZ0 D3ZT78 D3ZX01 D4AC36 F7F7A6 M0RD03 P04644 P05765 P13471 P17074 P24050 P24051 P27952 P29314 P38983 P49242 P60868 P62083 P62243 P62246 P62250 P62268 P62271 P62275 P62278 P62282 P62703 P62755 P62845 P62850 P62853 P62856 P62859 P62909 P62982 P63074 P63326 P68101 P81795 Q05474 Q1JU68 Q4G061 Q5RK09 Q5RKI1 Q5XI72 Q641X8 Q6AYK8 Q6P9U8 Q6VV72 Q71TY3 Q9EPH8	AABR07029195.1 EIF3EIP EIF3F EIF3K EIF3L EIF3M EIF3S12 EIF3S5 EIF3S6IP Eif1a Eif2a Eif2g Eif2s1 Eif2s2 Eif2s3 Eif2s3x Eif3a Eif3b Eif3c Eif3d Eif3e Eif3f Eif3g Eif3h Eif3i Eif3j Eif3k Eif3l Eif3m Eif3s1 Eif3s10 Eif3s2 Eif3s3 Eif3s4 Eif3s6 Eif3s7 Eif3s8 Eif3s9 Eif4a1 Eif4a2 Eif4e Eif4g1 Eif4h Fau Fte-1 Fte1 Int6 LOC100361854 LOC100361933 Lamr1 Pabp1 Pabpc1 Rig Rps10 Rps11 Rps12l8 Rps13 Rps14 Rps15 Rps15a Rps16 Rps17 Rps18 Rps19 Rps2 Rps20 Rps21 Rps23 Rps24 Rps25 Rps26 Rps26-ps13 Rps26l2 Rps26l4 Rps26l6 Rps27 Rps27a Rps27l Rps28 Rps29 Rps3 Rps3a Rps4 Rps4x Rps4y2 Rps5 Rps6 Rps7 Rps7-ps23 Rps8 Rps9 Rpsa S27-1 Uba80 Ubcep1 Wbscr1	Rattus norvegicus (Norway rat)
Multifunctional anion exchangers	Anion exchange transporter Chloride anion exchanger Pendrin Solute carrier family 26 member 11 Solute carrier family 26 member 6 Solute carrier family 26 member 9 Solute carrier family 5 member 12 Sulfate anion transporter 1 Sulfate transporter	A0A1W2Q610 D3Z9I5 D3ZV32 F1LWL8 F1M067 O70531 P45380 Q924C9 Q9R154	Dra Dtdst Pds Sat1 Slc26a1 Slc26a11 Slc26a2 Slc26a3 Slc26a4 Slc26a6 Slc26a7 Slc26a9 Slc5a12	Rattus norvegicus (Norway rat)
Interleukin-1 processing	Caspase-1 Cathepsin G Gasdermin D Interleukin-1 alpha Interleukin-1 beta Interleukin-18 Nuclear factor kappa B subunit 2 RELA proto-oncogene, NF-kB subunit	A0A096MJ11 A0A8I5ZMV7 A0A8I6G6F3 P16598 P17977 P43527 P97636 Q63264	Casp1 Ctsg Gsdmd Igif Il18 Il1a Il1b Il1bc Il1bce Nfkb2 Rela	Rattus norvegicus (Norway rat)
Metalloprotease DUBs	Abraxas 2, BRISC complex subunit BRCA1-A complex subunit Abraxas 1 BRCA1-A complex subunit RAP80 BRCA1-associated RING domain protein 1 BRISC and BRCA1-A complex member 1 BRISC and BRCA1-A complex member 2 Breast cancer type 1 susceptibility protein homolog Histone H2A type 2-A Histone H2A type 3 Histone H2A.J Histone H2A Histone H2A Histone H2A Histone acetyltransferase Lys-63-specific deubiquitinase BRCC36 Myb-like, SWIRM and MPN domain-containing protein 1 NACHT, LRR and PYD domains-containing protein 3 Polyubiquitin-B Polyubiquitin-C Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 14 STAM binding protein-like 1 STAM-binding protein Signal transducing adaptor molecule Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein histone acetyltransferase	A0A8I5Y222 A0A8I5ZYY0 A0A8I6A5Y3 A0A8I6AWT3 A0A8I6G641 A9UMV8 B2RYM5 B5DF55 D3ZVK7 D4A415 D4A523 D4A7T9 M0RA63 O54952 P0CC09 P0CG51 P62982 Q4FZT6 Q4V8E2 Q5I0F1 Q5PQK4 Q5XIJ6 Q63429 Q6P7Q1 Q8R424 Q9QZH2	ABRAXAS1 Abra1 Abraxas2 Amsh Babam1 Babam2 Bard1 Brca1 Brcc3 Brcc36 Bre Ccdc98 ENSRNOG00000062927 Ep300 Fam175a Fam175b H2ac10 H2ac18 H2ac25 H2ac4 H2aj Hist2h2aa3 Hist3h2a Kat2b LOC100360645 LOC120097726 Merit40 Mysm1 Nba1 Nlrp3 Psmd14 Rap80 Rps27a Stam Stambp Stambpl1 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Uimc1	Rattus norvegicus (Norway rat)
Synthesis of 5-eicosatetraenoic acids	Arachidonate 5-lipoxygenase-activating protein Leukotriene C4 synthase Polyunsaturated fatty acid 5-lipoxygenase Serum paraoxonase/arylesterase 1 Serum paraoxonase/arylesterase 2 Serum paraoxonase/lactonase 3	P12527 P20291 P55159 Q68FP2 Q6AXM8 Q925U2	Alox5 Alox5ap Flap Ltc4s Pon Pon1 Pon2 Pon3	Rattus norvegicus (Norway rat)
ISG15 antiviral mechanism	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 Beclin-1 E2 ubiquitin-conjugating enzyme E3 ubiquitin-protein ligase NEDD4 Eukaryotic initiation factor 4A-I Eukaryotic initiation factor 4A-II Eukaryotic initiation factor 4A-III Eukaryotic translation initiation factor 4 gamma 1 Eukaryotic translation initiation factor 4 gamma 2 Eukaryotic translation initiation factor 4 gamma, 3 Eukaryotic translation initiation factor 4E Filamin B ISG15 ubiquitin-like modifier Interferon regulatory factor 3 Interferon-induced GTP-binding protein Mx2 Interferon-induced protein with tetratricopeptide repeats 1B-like Interferon-induced, double-stranded RNA-activated protein kinase Mitogen-activated protein kinase 3 Protein phosphatase 1B RBR-type E3 ubiquitin transferase RNA helicase Signal transducer and activator of transcription 4 Tripartite motif-containing 25 Tyrosine-protein kinase Ubiquitin-like modifier activating enzyme 7 Ubiquitin/ISG15-conjugating enzyme E2 L6 ubiquitinyl hydrolase 1	A0A0G2JX93 A0A0G2JXT8 A0A0G2K735 A0A8I6A1T4 A0A8I6AM23 A0A8I6AMY8 A0A8I6APR1 D3ZXL1 D4A3X3 D4A9N5 D4ADT5 F1M3L4 F7EXX5 F7F7A6 M0RD03 P10686 P18589 P21708 P35815 P63074 Q3B8Q2 Q4V8J2 Q5RKI1 Q62940 Q63184 Q6AYC7 Q91XJ1	Arih1 Becn1 Ddx48 Eif2ak2 Eif4a1 Eif4a2 Eif4a3 Eif4e Eif4g1 Eif4g2 Eif4g3 Erk1 Flnb Ifit1bl Irf3 Isg15 Jak1 LOC100366017 Mapk3 Mx2 Nedd4 Nedd4a Plcg1 Pp2c2 Ppm1b Pppm1b Prkm3 Prkr Rig1 Rpf1 Stat1 Stat4 Trim25 Uba7 Ube2e1 Ube2l6 Usp18	Rattus norvegicus (Norway rat)
Synthesis of PA	1-acyl-sn-glycerol-3-phosphate acyltransferase delta 1-acyl-sn-glycerol-3-phosphate acyltransferase 1-acyl-sn-glycerol-3-phosphate acyltransferase 1-acylglycerol-3-phosphate O-acyltransferase 3 1-acylglycerol-3-phosphate O-acyltransferase 5 1-acylglycerol-3-phosphate O-acyltransferase 6 (Lysophosphatidic acid acyltransferase, zeta) Cytosolic phospholipase A2 DDHD domain containing 1 DDHD domain containing 2 Dihydroxyacetone phosphate acyltransferase Glycerol-3-phosphate acyltransferase 1, mitochondrial Glycerol-3-phosphate acyltransferase 2, mitochondrial Glycerol-3-phosphate acyltransferase 3 Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic Glycerol-3-phosphate dehydrogenase [NAD(+)] Glycerol-3-phosphate dehydrogenase, mitochondrial Group 10 secretory phospholipase A2 Intestinal-type alkaline phosphatase 1 Lipase I Lipase member H Lysocardiolipin acyltransferase 1 Lysophosphatidylcholine acyltransferase 1 Lysophosphatidylcholine acyltransferase 4 Mitochondrial cardiolipin hydrolase Mitoguardin 1 Mitoguardin 2 Phospholipase A2 group V Phospholipase A2, group XIIA Phospholipase A2, membrane associated Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase A2 Phospholipase D1 Phospholipase D2 Secretory phospholipase A2 receptor acid phosphatase	A0A0G2K2T2 A0A0G2KAE6 A0A8I5ZK24 A0A8I6AFV0 A0A8I6AUM0 B0K018 D3ZAP9 D3ZI76 D3ZLB5 D3ZMG4 D3ZQH6 D3ZR52 D4A1I6 D4AC45 D4ADQ2 F1M495 F7EQT9 F7F420 G3V648 G3V965 O35077 P04055 P14423 P15693 P35571 P50393 P51433 P70496 P70498 P97564 Q0ZFS7 Q1HAQ0 Q32PY2 Q4FZU0 Q4V8J4 Q924S1 Q9ES71 Q9QZT3	Acp6 Agpat1 Agpat2 Agpat3 Agpat4 Agpat5 Agpat6 Agpat9 Alpi Aytl2 Cpla2 Ddhd1 Ddhd2 Gnpat Gpam Gpat1 Gpat2 Gpat3 Gpat4 Gpd1 Gpd1l Gpd1l1 Gpd2 Lclat1 Liph Lipi Lpcat1 Lpcat4 Miga1 Miga2 Pla2g10 Pla2g12a Pla2g1b Pla2g2a Pla2g2d Pla2g2f Pla2g4 Pla2g4a Pla2g4b Pla2g4d Pla2g5 Pla2r1 Pld1 Pld2 Pld6 ddhd2	Rattus norvegicus (Norway rat)
Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)	Potassium channel subfamily K member 1 Potassium channel subfamily K member Potassium channel subfamily K member	D4A806 G3V8R8 Q9Z2T2	Kcnk1 Kcnk6 Kcnk7	Rattus norvegicus (Norway rat)
Regulation of PLK1 Activity at G2/M Transition	14-3-3 protein epsilon 14-3-3 protein gamma A-kinase anchoring protein 9 ALMS1, centrosome and basal body associated protein Alpha-centractin Aurora kinase A Beta-transducin repeat containing E3 ubiquitin protein ligase CDK5 regulatory subunit-associated protein 2 Casein kinase I isoform delta Centrin 2 Centriolar coiled-coil protein 110 Centromere protein J Centrosomal protein 131 Centrosomal protein 135 Centrosomal protein 152 Centrosomal protein 164 Centrosomal protein 192 Centrosomal protein 250 Centrosomal protein 290 Centrosomal protein 43 Centrosomal protein 72 Centrosomal protein 78 Centrosomal protein of 41 kDa Centrosomal protein of 57 kDa Centrosomal protein of 63 kDa Centrosomal protein of 70 kDa Centrosomal protein of 76 kDa Cullin 1 Cyclin-dependent kinase 1 Cytoplasmic dynein 1 heavy chain 1 Cytoplasmic dynein 1 intermediate chain 2 Cytoplasmic linker associated protein 1 Cytoskeleton associated protein 5 Dynactin 3-like 1 Dynactin subunit 1 Dynactin subunit 2 Dynein light chain 1, cytoplasmic F-box and WD repeat domain containing 11 Family with sequence similarity 29, member A G2/mitotic-specific cyclin-B1 G2/mitotic-specific cyclin-B2 G2/mitotic-specific cyclin-B2 HAUS augmin-like complex subunit 1 HAUS augmin-like complex subunit 8 HAUS augmin-like complex, subunit 4 HAUS augmin-like complex, subunit 5 HAUS augmin-like complex, subunit 7 Heat shock protein HSP 90-alpha LIM domain-containing protein ajuba Microtubule-associated protein RP/EB family member 1 NEDD1 gamma-tubulin ring complex targeting factor Ninein-like Nuclear distribution protein nudE homolog 1 Ofd1 centriole and centriolar satellite protein Optineurin Outer dense fiber protein 2 Pericentrin Pericentriolar material 1 Platelet-activating factor acetylhydrolase IB subunit alpha Polyubiquitin-B Polyubiquitin-C Protein aurora borealis Protein phosphatase 1 regulatory subunit 12A Protein phosphatase 1 regulatory subunit Protein phosphatase 2 scaffold subunit A alpha Ras-related protein Rab-8A S-phase kinase-associated protein 1 SFI1 centrin binding protein SHH signaling and ciliogenesis regulator SDCCAG8 SS nuclear autoantigen 1 Serine/threonine-protein kinase PLK1 Serine/threonine-protein kinase PLK4 Serine/threonine-protein phosphatase PP1-beta catalytic subunit Tubulin alpha-1A chain Tubulin alpha-4A chain Tubulin beta-4B chain Tubulin beta-5 chain Tubulin gamma-1 chain Ubiquitin B-like Ubiquitin-ribosomal protein eS31 fusion protein cAMP-dependent protein kinase catalytic subunit alpha cAMP-dependent protein kinase type II-beta regulatory subunit non-specific serine/threonine protein kinase non-specific serine/threonine protein kinase	A0A0G2JYQ1 A0A0G2K4Y6 A0A0G2K548 A0A0G2K929 A0A8I5Y0H0 A0A8I5ZRX6 A0A8I5ZSK7 A0A8I5ZUW5 A0A8I6A1X1 A0A8I6A3R0 A0A8I6A567 A0A8I6A5Y3 A0A8I6A773 A0A8I6AA62 A0A8I6ACI2 A0A8I6AEZ5 A0A8I6AHQ6 A0A8I6AIV4 A0A8I6ALB1 A0A8I6G2R1 A0A8I6GIW9 B2GUY1 B4F7A7 D3ZAH3 D3ZI35 D3ZIC4 D3ZMY8 D3ZTG6 D3ZVQ1 D4A194 D4A3J9 D4AB06 D4AEL8 F1LP29 F1M7J7 G3V931 G3V9W0 M0R9A9 P0CG51 P12369 P27791 P28023 P30277 P35280 P38650 P39951 P59241 P61983 P62142 P62260 P62982 P63004 P63170 P68370 P69897 P82995 P83888 P85515 Q06486 Q10728 Q4KLY0 Q4KM37 Q4V7C1 Q5BK57 Q5M857 Q5M864 Q5PQQ9 Q5U2Z2 Q5XI34 Q5XIF6 Q62673 Q62871 Q63429 Q66HR2 Q6AYC0 Q6AYH5 Q6AYX5 Q6P9T8 Q6PEC4 Q8R5M4 Q99PS2 Q9ES39 Q9JLH5 Q9R0A8	AABR07000222.1 Actr1a Aik Airk1 Ajuba Akap9 Alms1 Ark1 Aura Aurka Ayk1 Azi1 Bora Btak Btrc Ccdc5 Ccnb1 Ccnb2 Ccnb2-ps2 Ccp110 Cdc2 Cdc2a Cdk1 Cdk5rap2 Cdkn1 Cenpj Cep131 Cep135 Cep152 Cep164 Cep192 Cep250 Cep290 Cep41 Cep43 Cep57 Cep63 Cep70 Cep72 Cep76 Cep78 Cetn2 Ck1e-2 Ckap5 Clasp1 Csnk1d Csnk1e Ctrn1 Cul1 Dctn1 Dctn2 Dctn3l1 Dhc1 Dnch1 Dnchc1 Dnci2 Dncic2 Dncl1 Dnclc1 Dnec1 Dyhc Dync1h1 Dync1i2 Dynll1 Fbxw11 Fgfr1op Haus1 Haus4 Haus5 Haus6 Haus7 Haus8 Hckid Hice1 Hsp86 Hsp90aa1 Hspca Iak1 Jub LOC100360645 LOC309692 Lis-1 Lis1 Map1c Mapre1 Mbs Mypt1 Nde1 Nedd1 Nek2l1 Ninl Nude Nude1 Ny-sar-48 Odf2 Odf84 Ofd1 Optn Pafah1b1 Pafaha Pcm1 Pcnt Pin Plk Plk1 Plk4 Ppp1cb Ppp1r12a Ppp1r12b Ppp2r1a Prkaca Prkar2b Rab8 Rab8a Rps27a Sak Sdccag8 Sfi1 Skp1 Skp1a Ssna1 Stk15 Stk6 Tsga14 Tuba1 Tuba1a Tuba4 Tuba4a Tubb2c Tubb4b Tubb5 Tubg Tubg1 Uba80 Ubb Ubbl1 Ubc Ubcep1 Ubcl1 Ywhae Ywhag	Rattus norvegicus (Norway rat)
Synthesis of PIPs at the plasma membrane	ADP-ribosylation factor 1 Inositol polyphosphate 5-phosphatase OCRL Inositol polyphosphate-4-phosphatase type I A Inositol polyphosphate-5-phosphatase K Myotubularin related protein 14 Myotubularin-related protein 3 Myotubularin-related protein 6 Myotubularin Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma Phosphatidylinositol 3-kinase regulatory subunit alpha Phosphatidylinositol 3-kinase regulatory subunit beta Phosphatidylinositol 3-kinase regulatory subunit gamma Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A Phosphatidylinositol 4-kinase type 2-alpha Phosphatidylinositol 4-kinase type 2-beta Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha Phosphatidylinositol 4-phosphate 5-kinase type-1 beta Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha Phosphatidylinositol 5-phosphate 4-kinase type-2 beta Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma Phosphatidylinositol-3,5-bisphosphate 3-phosphatase Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha Phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta Phosphoinositide 3-kinase regulatory subunit 5 Phosphoinositide-3-kinase, regulatory subunit 6 Pleckstrin homology domain containing A1 Pleckstrin homology domain containing A2 Pleckstrin homology domain containing A5 Pleckstrin homology domain containing A6 Pleckstrin homology domain-containing family A member 4 Pleckstrin homology domain-containing family A member 8 RUN and FYVE domain containing 1 Ras-related protein Rab-14 Ras-related protein Rab-4A Ras-related protein Rab-5A Sesquipedalian Synaptojanin-1 Synaptojanin-2 Type II inositol 3,4-bisphosphate 4-phosphatase Tyrosine-protein kinase Tyrosine-protein phosphatase non-receptor type 13 phosphatidylinositol-4,5-bisphosphate 3-kinase phosphatidylinositol-4,5-bisphosphate 3-kinase	A0A0G2JXT6 A0A0G2K1A8 A0A0G2K1Q0 A0A0G2K2Z2 A0A0G2K344 A0A8I5Y1D5 A0A8I5Y949 A0A8I5ZTX1 A0A8I6AKY1 A0A8I6AU71 A0A8I6G5K9 A0A8I6G942 D3ZFJ0 D3ZGS3 D3ZMA2 D3ZSI8 D3ZTF6 D3ZY60 D4A4I3 E9PTG5 F1LR42 F1LVI0 G3V9S3 M0RC99 O55207 O70173 O88370 O88377 P05714 P60669 P61107 P84079 P97573 Q5CZZ9 Q5I6B8 Q5PQT2 Q5XIL2 Q62784 Q62910 Q63787 Q63788 Q63789 Q6AXQ4 Q99M64 Q9JMC1 Q9QWG5 Q9R0I8 Q9WVR3 Q9Z1L0	Arf1 Bmx Fapp2 Inpp4a Inpp4b Inpp5d Inpp5j Inpp5k Inppl1 Mtm1 Mtmr1 Mtmr14 Mtmr3 Mtmr6 Ocrl Pepp1 Pi4k2a Pi4k2b Pi4kii Pib5pa Pik3c2a Pik3c2b Pik3c2g Pik3ca Pik3cb Pik3cd Pik3cg Pik3r1 Pik3r2 Pik3r3 Pik3r5 Pik3r6 Pip4k2a Pip4k2b Pip4k2c Pip4ka Pip5k1a Pip5k1b Pip5k1c Pip5k2a Pip5k2b Pip5k2c Pipp Plekha1 Plekha2 Plekha3 Plekha4 Plekha5 Plekha6 Plekha8 Pten Ptpn13 Rab14 Rab4 Rab4a Rab5a Rufy1 Ship Ship1 Ship2 Synj1 Synj2	Rattus norvegicus (Norway rat)
DAP12 interactions	Beta-2-microglobulin C-type lectin domain containing 5A CD300 molecule-like family member b Cd300e molecule HLA class I histocompatibility antigen, A-24 alpha chain-like Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Ig-like domain-containing protein Killer cell immunoglobulin-like receptor 3DL1 Killer cell lectin like receptor C1 MHC class Ib antigen Natural killer cells antigen CD94 RT1 class I, M1, 5 RT1 class I, M1, gene 2 RT1 class I, M10, gene 1 RT1 class I, locus CE14 RT1 class I, locus CE16 RT1 class I, locus CE16 RT1 class I, locus CE3 RT1 class I, locus M1, gene 4 RT1 class Ia, locus A1 RT1 class Ia, locus A2 RT1 class Ib, locus M3, gene 1 RT1 class Ib, locus M5 RT1 class Ib, locus N3 RT1 class Ib, locus S3 Sialic acid binding Ig-like lectin 10 Sialic acid binding Ig-like lectin 15 Signal-regulatory protein alpha like 1 TYRO protein tyrosine kinase-binding protein Triggering receptor expressed on myeloid cells 1 Triggering receptor expressed on myeloid cells 2	A0A0G2JUX8 A0A0G2JVW0 A0A0G2K1E1 A0A0G2K4S5 A0A0G2K881 A0A8I5YC56 A0A8I5ZTS2 A0A8I5ZYQ2 A0A8I6ADU9 A0A8I6AK64 A0A8I6AL36 A0A8I6ASE5 A0A8I6GE62 A0A8I6GIX4 A0A8I6GMF6 A0A8J8XB15 A0A8J8Y6P7 A0A8J8YPS9 D3ZL05 D3ZPN6 D3ZZ89 D4ABU7 E9PTZ7 E9PTZ9 F1LQF2 F1MAR7 O35778 P07151 P83556 Q6MFZ3 Q6MFZ4 Q6W9J5 Q6X9T7	1700031A10Rik 2781a1 2788a1a2 2795a1 2800a1a2 2812a1a2 2824a1 2829a1a2 2846a1a2 2860a1 2865a2 2869a1a2 2879a1 2886a1-a1a2 2901a1a2 2906a1 2920a1a2 2927a1 2941a1a2 2945a1a2 2950a1 2953a1a2 2959a1 2976a1 2981a1a2 2984a1a2 2994a1 3082ex4-5 3252a3 3258a2 3281a3 3298a3 AABR07044308.2 AABR07044362.1 AABR07072807.1 AC120486.1 B2m Cd300e Cd300lb Cd94 Clec5a Dap12 ENSRNOG00000064836 ENSRNOG00000069480 H2-M10.6 H2-M10.6l Kir3dl1 Klrc1 Klrd1 LOC102546590 LOC120093125 Nerg-ps11 Nerg-ps12 Nerg-ps13 Nerg-ps14 Nerg-ps15 Pbp-ps Ppid-ps Ppp1cb-ps RT1-A1 RT1-A2 RT1-CE1 RT1-CE11 RT1-CE14 RT1-CE16 RT1-CE2 RT1-M1-1 RT1-M1-2 RT1-M1-3 RT1-M1-4 RT1-M1-5 RT1-M10-1 RT1-M10-2 RT1-M10-3 RT1-M10-4 RT1-M2 RT1-M3-1 RT1-M5 RT1-M7 RT1-M8 RT1-N3 RT1-O1l1 RT1-P2 RT1-S3 Rcrg1-ps25 Rcrg1-ps26 Rcrg1-ps27 Rcrg1-ps28 Rcrg1-ps29 Rcrg1-ps30 Rcrg1-ps31 Rcrg1-ps32 Rcrg1-ps33 Rcrg1-ps34 Rcrg1-ps35 Rcrg1-ps36 Rcrg1-ps37 Rcrg1-ps38 Rcrg1-ps39 Rcrg1-ps40 Rpl39-ps Siglec10 Siglec15 Sirpal1 Sirpd Trem1 Trem2 Trim15 Trim31 Trim39-ps Tyrobp	Rattus norvegicus (Norway rat)
ERKs are inactivated	Dual specificity protein phosphatase 4 Dual specificity protein phosphatase 6 Dual specificity protein phosphatase 7 Dual specificity protein phosphatase Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 Mitogen-activated protein kinase 7 Protein phosphatase 2 scaffold subunit A alpha Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform VRK serine/threonine kinase 3	A0A8I6A6K6 A0A8I6AF61 F7F2H0 P0C865 P21708 P62716 P63086 P63331 Q4QQT4 Q5XI34 Q62767 Q63340 Q64346	Bmk1 Dusp3 Dusp4 Dusp6 Dusp7 Erk1 Erk2 Erk5 Mapk Mapk1 Mapk3 Mapk7 Mkp2 Mkp3 Mkpx Ppp2ca Ppp2cb Ppp2r1a Ppp2r1b Ppp2r5d Prkm1 Prkm3 Vrk3	Rattus norvegicus (Norway rat)
Signal attenuation	Growth factor receptor-bound protein 10 Growth factor receptor-bound protein 2 Insulin receptor substrate 1 Insulin receptor substrate 2 Insulin receptor Insulin-1 Mitogen-activated protein kinase 1 Mitogen-activated protein kinase 3 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	D4A3T0 F1MAL5 P01322 P0CE43 P15127 P21708 P35570 P62994 P63086 Q5M824	Ash Erk1 Erk2 Grb10 Grb2 Ins-1 Ins1 Insr Irs-1 Irs1 Irs2 Mapk Mapk1 Mapk3 Prkm1 Prkm3 Shc1 Sos1	Rattus norvegicus (Norway rat)
cGMP effects	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A Inositol 1,4,5-triphosphate receptor associated 1 Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1 Phosphodiesterase cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A cGMP-dependent 3',5'-cyclic phosphodiesterase cGMP-dependent protein kinase 2 cGMP-dependent protein kinase cGMP-specific 3',5'-cyclic phosphodiesterase	A0A8I6A416 A0A8I6A9E8 D3ZDF3 O54735 P29994 Q01062 Q01066 Q64595 Q8QZV1 Q8VID6 Q9QYJ6	AABR07006724.1 Insp3r Irag1 Itpr1 Mrvi1 Pde10a Pde11a Pde1a Pde1b Pde1b1 Pde2a Pde5 Pde5a Pde9a Prkg1 Prkg2	Rattus norvegicus (Norway rat)
Tight junction interactions	Junctional adhesion molecule A Par-6 family cell polarity regulator beta Par-6 family cell polarity regulator gamma Partitioning defective 3 homolog Partitioning defective 6 homolog alpha Protein kinase C iota type	D4A2F2 E9PT71 F1M7Y5 Q6B4M5 Q9JHY1 Q9Z340	F11r Jam1 Par-6a Par3 Par6a Pard3 Pard6a Pard6b Pard6g Pkcl Prkci	Rattus norvegicus (Norway rat)
CS/DS degradation	Alpha-L-iduronidase Arylsulfatase B Beta-hexosaminidase subunit alpha Beta-hexosaminidase subunit beta Biglycan Brevican core protein Chondroitin sulfate proteoglycan 4 Chondroitin sulfate proteoglycan 5 Decorin Hyaluronidase-1 Hyaluronidase-3 Iduronate 2-sulfatase Neurocan core protein Versican core protein (Fragments)	D3ZE16 F1LLW8 P47853 P50430 P55067 P55068 Q00657 Q01129 Q641X3 Q6AXR4 Q76HM9 Q76HN1 Q9ERB4 Q9ERQ6	Arsb Bcan Behab Bgn Caleb Cspg2 Cspg3 Cspg4 Cspg5 Dcn Hexa Hexb Hyal1 Hyal3 Ids Idua LOC100363795 Ncan Ng2 Ngc Vcan	Rattus norvegicus (Norway rat)	G27025MB
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)	Cartilage intermediate layer protein Insulin-like growth factor 1 receptor Insulin-like growth factor I Insulin-like growth factor II	D3ZGB8 P01346 P08025 P24062	Cilp Igf-1 Igf-2 Igf1 Igf1r Igf2	Rattus norvegicus (Norway rat)
SHC-mediated cascade:FGFR3	Fibroblast growth factor 16 Fibroblast growth factor 17 Fibroblast growth factor 18 Fibroblast growth factor 1 Fibroblast growth factor 20 Fibroblast growth factor 23 Fibroblast growth factor 2 Fibroblast growth factor 5 Fibroblast growth factor 9 Fibroblast growth factor receptor Fibroblast growth factor Fibroblast growth factor GTPase HRas GTPase KRas GTPase NRas Growth factor receptor-bound protein 2 SHC-transforming protein 1 SOS Ras/Rac guanine nucleotide exchange factor 1	A0A0G2K210 A0A8I6B5D5 D4A3T0 F1LSQ8 O54769 O88182 P08644 P13109 P20171 P36364 P48807 P61149 P62994 P63076 Q04970 Q5M824 Q8VI82 Q9EST9	Ash Fgf-1 Fgf-2 Fgf-5 Fgf-9 Fgf1 Fgf16 Fgf17 Fgf18 Fgf2 Fgf20 Fgf23 Fgf4 Fgf5 Fgf7a Fgf8 Fgf9 Fgfa Fgfr3 Grb2 Hras Hras1 Kras Kras2 Nras Shc1 Sos1	Rattus norvegicus (Norway rat)
Tandem pore domain halothane-inhibited K+ channel (THIK)	Potassium channel subfamily K member 13	Q9ERS0	Kcnk13	Rattus norvegicus (Norway rat)
Glucuronidation	Palmitoyl-protein thioesterase ABHD10, mitochondrial UDP-glucuronosyltransferase 1-2 UDP-glucuronosyltransferase 1-6 UDP-glucuronosyltransferase 1A1 UDP-glucuronosyltransferase 1A3 UDP-glucuronosyltransferase 1A5 UDP-glucuronosyltransferase 1A7 UDP-glucuronosyltransferase 1A8 UDP-glucuronosyltransferase 2A1 UDP-glucuronosyltransferase 2B15 UDP-glucuronosyltransferase 2B17 UDP-glucuronosyltransferase 2B1 UDP-glucuronosyltransferase 2B2 UDP-glucuronosyltransferase 2B37 UDP-glucuronosyltransferase 2B7 UDP-glucuronosyltransferase glucuronosyltransferase	A0A0G2K4R2 F1LTB8 P08430 P08541 P08542 P09875 P19488 P20720 P36510 P36511 Q5I0K5 Q62789 Q64550 Q64633 Q64634 Q64637 Q64638	Abhd10 RGD1559459 Udpgtr2 Ugt1 Ugt1a1 Ugt1a2 Ugt1a3 Ugt1a5 Ugt1a6 Ugt1a7 Ugt1a7c Ugt1a8 Ugt2a-1 Ugt2a1 Ugt2b Ugt2b1 Ugt2b12 Ugt2b15 Ugt2b17 Ugt2b2 Ugt2b3 Ugt2b34l1 Ugt2b36 Ugt2b37 Ugt2b4 Ugt2b5 Ugt2b6 Ugt2b7 Ugt2b8 Ugt3a1 Ugt3a2	Rattus norvegicus (Norway rat)

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