GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **250** in total

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Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism
Activation of the AP-1 family of transcription factors	ATF/CREB activator 1 ATF/CREB activator 2 CRE-binding bZIP protein SKO1 General control transcription factor GCN4 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase HOG1 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P03069 P14681 P16892 P32485 P39970 P40535 P41808 Q00772 Q02100	AAS101 AAS3 ACA1 ACA2 ACR1 ARG9 CST6 DAC2 FUS3 GCN4 HOG1 KSS1 MPK1 SKO1 SLT2 SMK1 SSK3	Saccharomyces cerevisiae (brewer's yeast)
Fatty acyl-CoA biosynthesis	3-oxoacyl-[acyl-carrier-protein] reductase Acetyl-CoA carboxylase Acyl-CoA desaturase 1 Very long-chain fatty acid transport protein	P21147 P35731 P38225 Q00955	ABP2 ACC1 FAS3 FAT1 MTR7 OAR1 OLE1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PC	Choline kinase Choline-phosphate cytidylyltransferase Choline/ethanolaminephosphotransferase 1 Cholinephosphotransferase 1 Ethanolamine kinase Medium-chain fatty acid ethyl ester synthase/esterase 1 Medium-chain fatty acid ethyl ester synthase/esterase 2 Monoacylglycerol lipase Phosphatidic acid phosphohydrolase 1 Phosphatidyl-N-methylethanolamine N-methyltransferase	P05375 P13259 P17898 P20485 P22140 P32567 P38295 Q02891 Q03649 Q03764	CCT CCT1 CKI CKI1 CPT1 EEB1 EHT1 EKI1 EPT1 MGL2 OPI3 PAH1 PAP1 PCT1 PEM2 SMP2	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the late endosome membrane	Phosphatidylinositol 3-kinase VPS34 Phosphoinositide 3-phosphatase Serine/threonine-protein kinase VPS15	P22219 P22543 P47147	END12 GRD8 PEP15 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29 YMR1	Saccharomyces cerevisiae (brewer's yeast)
Presynaptic phase of homologous DNA pairing and strand exchange	DNA repair protein RAD51 Serine/threonine-protein kinase KSP1	P25454 P38691	KSP1 RAD51	Saccharomyces cerevisiae (brewer's yeast)
Deadenylation of mRNA	ATP-dependent RNA helicase FAL1 ATP-dependent RNA helicase eIF4A Eukaryotic initiation factor 4F subunit p150 Eukaryotic translation initiation factor 4B Eukaryotic translation initiation factor 4E Nucleolar protein 13 PAN2-PAN3 deadenylation complex catalytic subunit PAN2 PAN2-PAN3 deadenylation complex subunit PAN3 Protein PES4	P07260 P10081 P34167 P36102 P39684 P39935 P53010 P53883 Q12099	CDC33 ECM35 FAL1 NOP13 PAN2 PAN3 PES4 STM1 TIF1 TIF2 TIF3 TIF41A TIF41B TIF42 TIF45 TIF4631	Saccharomyces cerevisiae (brewer's yeast)
RHOC GTPase cycle	Delta(14)-sterol reductase ERG24 GTP-binding protein RHO1 GTP-binding protein RHO2 GTP-binding protein RHO3 GTP-binding protein RHO4 Integral membrane protein SED5 Mitochondrial acidic protein MAM33 Protein ECM25 Protein EMP46 Protein EMP47 Protein UIP5 Protein kinase C-like 1 Putative zinc metalloprotease TRE2 Ras GTPase-activating-like protein IQG1 Rho GDP-dissociation inhibitor Uncharacterized protein TRE1 Vacuolar protein sorting-associated protein 70 Vesicle-associated membrane protein-associated protein SCS22 Vesicle-associated membrane protein-associated protein SCS2	P06780 P06781 P24583 P32462 P32525 P36137 P40075 P40513 P43555 P47161 Q00245 Q00246 Q01590 Q08693 Q08919 Q12280 Q12396 Q12434 Q6Q595	CYK1 ECM25 EMP46 EMP47 ERG24 HPO2 IQG1 MAM33 PKC1 RDI1 RHO1 RHO2 RHO3 RHO4 SCS2 SCS22 SED5 STT1 TRE1 TRE2 UIP5 VPS70	Saccharomyces cerevisiae (brewer's yeast)
Vitamin B2 (riboflavin) metabolism	Ectonucleotide pyrophosphatase/phosphodiesterase 1 Ectonucleotide pyrophosphatase/phosphodiesterase 2 Flavin adenine dinucleotide synthase Riboflavin kinase	P25353 P38913 P39997 Q03778	FAD1 FMN1 NPP1 NPP2	Saccharomyces cerevisiae (brewer's yeast)
Oleoyl-phe metabolism	Carboxypeptidase S	P27614	CPS CPS1	Saccharomyces cerevisiae (brewer's yeast)
Acyl chain remodeling of DAG and TAG	Diacylglycerol O-acyltransferase 1 Monoglyceride lipase	P28321 Q08650	DGA1 YJU3	Saccharomyces cerevisiae (brewer's yeast)
CLEC7A (Dectin-1) signaling	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 Protein kinase C-like 1	P24583 P32383	HPO2 PKC1 PLC1 STT1	Saccharomyces cerevisiae (brewer's yeast)
Biotin transport and metabolism	Acetyl-CoA carboxylase, mitochondrial Acetyl-CoA carboxylase Biotin--protein ligase Pyruvate carboxylase 1	P11154 P32874 P48445 Q00955	ABP2 ACC1 ACC2 BPL1 FAS3 HFA1 MTR7 PYC1 PYV	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	Polyubiquitin Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase YUH1 Ubiquitin-activating enzyme E1 1 Ubiquitin-conjugating enzyme E2 1 Ubiquitin-conjugating enzyme E2 2 Ubiquitin-conjugating enzyme E2 4 Ubiquitin-conjugating enzyme E2 7 Ubiquitin-conjugating enzyme E2-16 kDa Ubiquitin-conjugating enzyme E2-18 kDa Ubiquitin-conjugating enzyme E2-24 kDa Ubiquitin-conjugating enzyme E2-34 kDa	P06104 P0CG63 P14682 P15731 P15732 P21734 P22515 P28263 P35127 P50101 P52492 Q02159	CDC34 DNA6 GID3 QRI8 RAD6 SCD2 UBA1 UBC1 UBC11 UBC2 UBC3 UBC4 UBC5 UBC7 UBC8 UBI4 UBP15 YUH1	Saccharomyces cerevisiae (brewer's yeast)
Hydrolysis of LPC	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1 Uncharacterized protein YJR098C	P39105 P47139 P53541 Q03674 Q08108	PLB1 PLB2 PLB3 SPO1 YJR098C	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of IP2, IP, and Ins in the cytosol	Inositol monophosphatase 1 Inositol monophosphatase 2 Inositol-3-phosphate synthase Phosphatidylinositol 4,5-bisphosphate 5-phosphatase INP54 Polyphosphatidylinositol phosphatase INP53	P11986 P38710 Q05533 Q08227 Q12271	IMP1 IMP2 INM1 INM2 INO1 INP53 INP54 SJL3 SOP2	Saccharomyces cerevisiae (brewer's yeast)
Regulation of pyruvate metabolism	E3 ubiquitin-protein ligase RMD5 Glucose-induced degradation protein 7 Glucose-induced degradation protein 8 Polyubiquitin Protein FYV10 Pyruvate kinase 1 Pyruvate kinase 2 Vacuolar import and degradation protein 28 Vacuolar import and degradation protein 30	P00549 P0CG63 P25569 P40208 P40492 P40547 P52489 P53076 Q12508	CDC19 DCR1 FYV10 GID1 GID2 GID5 GID7 GID8 GID9 MOH2 PYK1 PYK2 RMD5 SCD2 UBI4 VID28 VID30	Saccharomyces cerevisiae (brewer's yeast)
Cholesterol biosynthesis	3-hydroxy-3-methylglutaryl-coenzyme A reductase 1 Acetyl-CoA acetyltransferase C-4 methylsterol oxidase ERG25 Delta(14)-sterol reductase ERG24 Diphosphomevalonate decarboxylase Dolichyldiphosphatase Farnesyl pyrophosphate synthase Geranylgeranyl pyrophosphate synthase BTS1 Hydroxymethylglutaryl-CoA synthase Isopentenyl-diphosphate delta-isomerase Lanosterol 14-alpha demethylase CYP51 Lanosterol synthase ERG7 Mevalonate kinase Protein ARV1 Squalene epoxidase ERG1 Squalene synthase ERG9 Sterol-4-alpha-carboxylate 3-dehydrogenase ERG26, decarboxylating	P07277 P08524 P10614 P12683 P15496 P29704 P32377 P32462 P32476 P38604 P41338 P53045 P53199 P53223 P54839 Q06541 Q12051	ARV1 BOT2 BOT3 BTS1 CAX4 CWH8 CYP51 ERG1 ERG10 ERG11 ERG12 ERG13 ERG19 ERG20 ERG24 ERG25 ERG26 ERG7 ERG9 FDS1 FET6 FPP1 HMG1 HMGS IDI1 MPD MVD1 RAR1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the Golgi membrane	ADP-ribosylation factor 1 ADP-ribosylation factor 2 Phosphatidylinositol 3-kinase VPS34 Phosphatidylinositol 4-kinase LSB6 Phosphatidylinositol 4-kinase PIK1 Phosphatidylinositol 4-kinase STT4 Phosphatidylinositol-3-phosphatase SAC1 Probable phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TEP1 Serine/threonine-protein kinase VPS15	P11076 P19146 P22219 P22543 P32368 P37297 P39104 P42951 P53916	ARF1 ARF2 END12 GRD8 LSB6 PEP15 PIK1 RSD1 SAC1 STT4 TEP1 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29	Saccharomyces cerevisiae (brewer's yeast)
Wax biosynthesis	Diacylglycerol O-acyltransferase 1	Q08650	DGA1	Saccharomyces cerevisiae (brewer's yeast)
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion	Bud site selection protein 5 Cell division control protein 25 Guanine nucleotide exchange factor LTE1 Ras-related protein RSR1	P04821 P07866 P13856 P25300	BUD1 BUD5 CDC25 CTN1 EIS4 LTE1 MSI2 RSR1	Saccharomyces cerevisiae (brewer's yeast)
Class I peroxisomal membrane protein import	Fatty aldehyde dehydrogenase HFD1 Mitochondrial fission 1 protein Outer mitochondrial transmembrane helix translocase Peroxisomal biogenesis factor 3 Peroxisomal long-chain fatty acid import protein 1 Peroxisomal long-chain fatty acid import protein 2 Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal membrane protein PMP27 Peroxisomal membrane protein import receptor PEX19 Peroxisome assembly protein 12	P28737 P28795 P34230 P40515 P41909 P53112 P80667 Q04370 Q04458 Q07418 Q12462	FIS1 HFD1 MDV2 MSP1 PAL1 PAS12 PAS20 PAS3 PAT1 PAT2 PEX11 PEX12 PEX13 PEX14 PEX19 PEX3 PMP24 PMP27 PXA1 PXA2 SSH2 YTA4	Saccharomyces cerevisiae (brewer's yeast)
ERKs are inactivated	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Protein phosphatase PP2A regulatory subunit A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase PP2A-1 catalytic subunit Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P23594 P31383 P38903 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 PPH21 RTS1 SCS1 SLT2 SMK1 TPD3	Saccharomyces cerevisiae (brewer's yeast)
Mitochondrial protein degradation	2-oxoglutarate dehydrogenase, mitochondrial 3-oxoacyl-[acyl-carrier-protein] synthase homolog ADP,ATP carrier protein 1 ADP,ATP carrier protein 2 ADP,ATP carrier protein 3 ARS-binding factor 2, mitochondrial ATP synthase subunit 5, mitochondrial ATP synthase subunit a ATP synthase subunit alpha, mitochondrial ATP synthase subunit beta, mitochondrial ATP synthase subunit d, mitochondrial ATP synthase subunit g, mitochondrial ATP synthase subunit gamma, mitochondrial Aconitate hydratase, mitochondrial Aldehyde dehydrogenase 5, mitochondrial Arginase Citrate synthase, mitochondrial Cytochrome b-c1 complex subunit 8, mitochondrial Cytochrome c oxidase subunit 1 Cytochrome c oxidase subunit 4, mitochondrial Cytochrome c oxidase subunit 6, mitochondrial D-lactate dehydrogenase [cytochrome] 1, mitochondrial Ferrochelatase, mitochondrial Fumarate hydratase, mitochondrial Gamma-glutamyl phosphate reductase Heat shock protein 60, mitochondrial High mobility group protein 1 Hydroxymethylglutaryl-CoA synthase Import motor subunit, mitochondrial Intrastrand cross-link recognition protein Isoleucine--tRNA ligase, mitochondrial Large ribosomal subunit protein bL12m Large ribosomal subunit protein bL32m Lon protease homolog, mitochondrial Magnesium-activated aldehyde dehydrogenase, cytosolic Malate dehydrogenase, cytoplasmic Mitochondrial inner membrane m-AAA protease component YTA10 Mitochondrial inner membrane m-AAA protease component YTA12 Mitochondrial-processing peptidase subunit alpha Non-histone chromosomal protein 6A Non-histone protein 10 Potassium-activated aldehyde dehydrogenase, mitochondrial Pyruvate dehydrogenase E1 component subunit beta, mitochondrial Single-stranded DNA-binding protein RIM1, mitochondrial Small ribosomal subunit protein uS2m cAMP-dependent protein kinase type 2	P00401 P00427 P00812 P00830 P00854 P00890 P04037 P04710 P06245 P07251 P08417 P08525 P09457 P0CS90 P11632 P11914 P16622 P18238 P18239 P19414 P19882 P20967 P22133 P25348 P30902 P32445 P32473 P32891 P32902 P33417 P36775 P38077 P39525 P39925 P40047 P40341 P46367 P48526 P53163 P54115 P54839 P54885 Q02486 Q03435 Q03973 Q12233	AAC1 AAC2 AAC3 ABF2 ACO1 AFG3 ALD3 ALD4 ALD5 ALD6 ALD7 ALDH1 ALDH2 ALDH5 ATP1 ATP2 ATP20 ATP3 ATP3a ATP3b ATP5 ATP6 ATP7 CAR1 CEM1 CIT1 COX1 COX4 COX6 DLD DLD1 ENS1 ERG13 FUM1 GLU1 GLU3 HEM15 HIM1 HMGS HMO1 HMO2 HSM2 HSP60 ISM1 IXR1 KGD1 LON LYS6 MAS2 MDH2 MIF2 MIF4 MNP1 MRP4 MRP4A MRPL12 MRPL32 NHP10 NHP6A NHPA OGD1 OLI2 OLI4 ORD1 OSCP OXI3 PDB1 PET9 PHO1 PIM1 PKA2 PRO2 QCR8 RCA1 RIM1 SSC1 TPK2 YKR1 YTA10 YTA12	Saccharomyces cerevisiae (brewer's yeast)
Formation of the Early Elongation Complex	Cyclin CCL1 DNA-directed RNA polymerase II subunit RPB11 DNA-directed RNA polymerase II subunit RPB1 DNA-directed RNA polymerase II subunit RPB2 DNA-directed RNA polymerase II subunit RPB3 DNA-directed RNA polymerase II subunit RPB4 DNA-directed RNA polymerase II subunit RPB7 DNA-directed RNA polymerase II subunit RPB9 DNA-directed RNA polymerases I, II, and III subunit RPABC1 DNA-directed RNA polymerases I, II, and III subunit RPABC2 DNA-directed RNA polymerases I, II, and III subunit RPABC3 DNA-directed RNA polymerases I, II, and III subunit RPABC4 DNA-directed RNA polymerases I, II, and III subunit RPABC5 General transcription and DNA repair factor IIH helicase subunit XPD General transcription and DNA repair factor IIH helicase/translocase subunit XPB/SSL2 General transcription and DNA repair factor IIH subunit SSL1 General transcription and DNA repair factor IIH subunit TFB1 General transcription and DNA repair factor IIH subunit TFB2 General transcription and DNA repair factor IIH subunit TFB4 General transcription and DNA repair factor IIH subunit TFB5 Nuclear cap-binding protein complex subunit 1 Nuclear cap-binding protein subunit 2 RNA polymerase II subunit A C-terminal domain phosphatase RNA polymerase II transcription factor B subunit 3 Serine/threonine-protein kinase KIN28 Transcription elongation factor SPT4 Transcription elongation factor SPT5 Transcription initiation factor IIF subunit alpha Transcription initiation factor IIF subunit beta	P04050 P06242 P06839 P08518 P16370 P20433 P20434 P20435 P20436 P22139 P27692 P27999 P32776 P32914 P34087 P34160 P37366 P38902 P40422 P41895 P41896 Q00578 Q02939 Q03254 Q03290 Q04673 Q08920 Q12004 Q3E7C1	CBC1 CBC2 CBP20 CBP80 CCL1 FCP1 GCR3 KIN28 LOM3 MUD13 RAD25 RAD3 REM1 RIG2 RPA7 RPB1 RPB10 RPB11 RPB12 RPB150 RPB2 RPB220 RPB3 RPB4 RPB5 RPB6 RPB7 RPB8 RPB9 RPC10 RPC9 RPO21 RPO22 RPO26 SAE1 SPT4 SPT5 SSL1 SSL2 SSU71 STO1 SUA8 SUT1 TFB1 TFB2 TFB3 TFB4 TFB5 TFG1 TFG2 UVS112	Saccharomyces cerevisiae (brewer's yeast)
alpha-linolenic acid (ALA) metabolism	3-ketoacyl-CoA thiolase, peroxisomal Fatty acid elongase 1 Fatty acid elongase 2 Fatty acid elongase 3 Peroxisomal acyl-coenzyme A thioester hydrolase 1 Peroxisomal long-chain fatty acid import protein 2	P25358 P27796 P39540 P40319 P41903 P41909	APA1 ELO1 ELO2 ELO3 FEN1 FOX3 GNS1 PAL1 PAT2 POT1 POX3 PTE1 PXA1 SRE1 SSH2 SUR4 TES1 VBM1 VBM2	Saccharomyces cerevisiae (brewer's yeast)

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