GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying entries **26 - 50** of **250** in total

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Pathway Name	Protein Name ▼	UniProt ID	Gene Symbol	Organism
Ciprofloxacin ADME	Probable ATP-dependent permease	P25371	ADP1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes	Polyubiquitin Ubiquitin carboxyl-terminal hydrolase 15 Ubiquitin carboxyl-terminal hydrolase YUH1 Ubiquitin-activating enzyme E1 1 Ubiquitin-conjugating enzyme E2 1 Ubiquitin-conjugating enzyme E2 2 Ubiquitin-conjugating enzyme E2 4 Ubiquitin-conjugating enzyme E2 7 Ubiquitin-conjugating enzyme E2-16 kDa Ubiquitin-conjugating enzyme E2-18 kDa Ubiquitin-conjugating enzyme E2-24 kDa Ubiquitin-conjugating enzyme E2-34 kDa	P06104 P0CG63 P14682 P15731 P15732 P21734 P22515 P28263 P35127 P50101 P52492 Q02159	CDC34 DNA6 GID3 QRI8 RAD6 SCD2 UBA1 UBC1 UBC11 UBC2 UBC3 UBC4 UBC5 UBC7 UBC8 UBI4 UBP15 YUH1	Saccharomyces cerevisiae (brewer's yeast)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling	Phosphatidylinositol 4-phosphate 5-kinase MSS4 Protein phosphatase PP2A regulatory subunit A Serine/threonine-protein kinase SCH9 Serine/threonine-protein kinase YPK1 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase PP2A-1 catalytic subunit	P11792 P12688 P23594 P31383 P38903 P38994	KOM1 MSS4 PPH21 RTS1 SCH9 SCS1 SLI2 TPD3 YPK1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the late endosome membrane	Phosphatidylinositol 3-kinase VPS34 Phosphoinositide 3-phosphatase Serine/threonine-protein kinase VPS15	P22219 P22543 P47147	END12 GRD8 PEP15 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29 YMR1	Saccharomyces cerevisiae (brewer's yeast)
Synthesis of PIPs at the early endosome membrane	Phosphatidylinositol 3-kinase VPS34 Phosphatidylinositol 4-kinase LSB6 Phosphoinositide 3-phosphatase Serine/threonine-protein kinase VPS15	P22219 P22543 P42951 P47147	END12 GRD8 LSB6 PEP15 VAC4 VPL19 VPL7 VPS15 VPS34 VPT29 YMR1	Saccharomyces cerevisiae (brewer's yeast)
E3 ubiquitin ligases ubiquitinate target proteins	Peroxisomal membrane protein PEX13 Peroxisomal membrane protein PEX14 Peroxisomal targeting signal receptor Peroxisome assembly protein 12 Peroxisome biogenesis factor 10 Polyubiquitin Postreplication repair E3 ubiquitin-protein ligase RAD18 Proliferating cell nuclear antigen Ubiquitin-conjugating enzyme E2 13 Ubiquitin-conjugating enzyme E2 2 Ubiquitin-conjugating enzyme E2 4 Ubiquitin-conjugating enzyme E2-16 kDa Ubiquitin-conjugating enzyme variant MMS2 Uncharacterized ATP-dependent helicase IRC20	P06104 P0CG63 P10862 P15731 P15732 P15873 P35056 P52490 P53112 P53152 P80667 Q04370 Q05568 Q06554	IRC20 MMS2 PAS10 PAS20 PAS4 PEX10 PEX12 PEX13 PEX14 PEX5 POL30 RAD18 RAD6 SCD2 UBC13 UBC2 UBC4 UBC5 UBI4	Saccharomyces cerevisiae (brewer's yeast)
ABC transporters in lipid homeostasis	Peroxisomal biogenesis factor 3 Peroxisomal long-chain fatty acid import protein 1 Peroxisomal long-chain fatty acid import protein 2 Peroxisomal membrane protein import receptor PEX19 Probable ATP-dependent permease Uncharacterized ABC transporter ATP-binding protein/permease YOL075C	P25371 P28795 P34230 P41909 Q07418 Q08234	ADP1 PAL1 PAS12 PAS3 PAT1 PAT2 PEX19 PEX3 PXA1 PXA2 SSH2 YOL075C	Saccharomyces cerevisiae (brewer's yeast)
Transport of RCbl within the body	Oligomycin resistance ATP-dependent permease YOR1	P53049	YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
Cytoprotection by HMOX1	Oligomycin resistance ATP-dependent permease YOR1	P53049	YOR1 YRS1	Saccharomyces cerevisiae (brewer's yeast)
SUMOylation of RNA binding proteins	Nuclear polyadenylated RNA-binding protein 3 Nucleolar protein 58 Nucleoporin ASM4 Nucleoporin NDC1 Nucleoporin NIC96 Nucleoporin NSP1 Nucleoporin NUP116/NSP116 Nucleoporin NUP120 Nucleoporin NUP133 Nucleoporin NUP170 Nucleoporin NUP188 Nucleoporin NUP192 Nucleoporin NUP1 Nucleoporin NUP2 Nucleoporin NUP42 Nucleoporin NUP57 Nucleoporin NUP82 Nucleoporin NUP84 Nucleoporin NUP85 Nucleoporin SEH1 Protein MLP1 Protein transport protein SEC13 Ran-specific GTPase-activating protein 1 Ran-specific GTPase-activating protein 2 SUMO-conjugating enzyme UBC9 Ubiquitin-like protein SMT3 mRNA export factor GLE2	P14907 P20676 P32499 P32500 P34077 P35729 P36161 P38181 P38996 P40066 P40368 P40517 P41920 P46673 P47054 P48837 P49686 P50623 P52593 P52891 P53011 Q02455 Q02630 Q04491 Q05166 Q12306 Q12499	ANU3 ASM4 CST20 GLE2 HMD1 HTN1 MLP1 NAB3 NDC1 NIC96 NLE3 NOP5 NOP58 NSP1 NSP116 NUP1 NUP116 NUP120 NUP133 NUP170 NUP188 NUP192 NUP2 NUP42 NUP57 NUP59 NUP82 NUP84 NUP85 RAE1 RAT2 RAT3 RAT9 RIP1 SEC13 SEH1 SFO1 SMT3 UBC9 UIP1 YRB1 YRB2	Saccharomyces cerevisiae (brewer's yeast)
Intestinal lipid absorption	NPC intracellular sterol transporter 1-related protein 1	Q12200	NCR1	Saccharomyces cerevisiae (brewer's yeast)
Inositol transporters	Myo-inositol transporter 1	P30605	ITR1	Saccharomyces cerevisiae (brewer's yeast)
RAF/MAP kinase cascade	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 SLT2 SMK1	Saccharomyces cerevisiae (brewer's yeast)
RAF-independent MAPK1/3 activation	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 SLT2 SMK1	Saccharomyces cerevisiae (brewer's yeast)
Negative regulation of MAPK pathway	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Sporulation-specific mitogen-activated protein kinase SMK1 Tyrosine-protein phosphatase 1 Tyrosine-protein phosphatase 2 Tyrosine-protein phosphatase 3	P14681 P16892 P25044 P29461 P40048 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 PTP1 PTP2 PTP3 SLT2 SMK1	Saccharomyces cerevisiae (brewer's yeast)
ERKs are inactivated	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Protein phosphatase PP2A regulatory subunit A Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase PP2A-1 catalytic subunit Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P23594 P31383 P38903 P41808 Q00772	DAC2 FUS3 KSS1 MPK1 PPH21 RTS1 SCS1 SLT2 SMK1 TPD3	Saccharomyces cerevisiae (brewer's yeast)
ERK/MAPK targets	Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase HOG1 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Protein phosphatase PP2A regulatory subunit A Serine/threonine-protein kinase YPK3 Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform Serine/threonine-protein phosphatase PP2A-1 catalytic subunit Sporulation-specific mitogen-activated protein kinase SMK1	P14681 P16892 P23594 P31383 P32485 P38070 P38903 P41808 Q00772	DAC2 FUS3 HOG1 KSS1 MPK1 PPH21 RTS1 SCS1 SLT2 SMK1 SSK3 TPD3 YPK3	Saccharomyces cerevisiae (brewer's yeast)
Glycerophospholipid biosynthesis	Mitochondrial import inner membrane translocase subunit TIM54 Sphingoid long chain base kinase 4 Sphingoid long chain base kinase 5	P47045 Q06147 Q12246	LCB4 LCB5 TIM54	Saccharomyces cerevisiae (brewer's yeast)
Zinc influx into cells by the SLC39 gene family	Metal homeostasis factor ATX2 Zinc transporter YKE4	P40544 Q12067	ATX2 YKE4	Saccharomyces cerevisiae (brewer's yeast)
Signal transduction by L1	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
MAPK1 (ERK2) activation	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
Negative feedback regulation of MAPK pathway	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
MAP2K and MAPK activation	MAP kinase kinase MKK1/SSP32 MAP kinase kinase MKK2/SSP33 MAP kinase kinase PBS2 Mitogen-activated protein kinase FUS3 Mitogen-activated protein kinase KSS1 Mitogen-activated protein kinase SLT2/MPK1 Serine/threonine-protein kinase STE7 Sporulation-specific mitogen-activated protein kinase SMK1	P06784 P08018 P14681 P16892 P32490 P32491 P41808 Q00772	DAC2 FUS3 HOG4 KSS1 MKK1 MKK2 MPK1 PBS2 SFS4 SLT2 SMK1 SSK4 SSP32 SSP33 STE7	Saccharomyces cerevisiae (brewer's yeast)
Hydrolysis of LPE	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1	P39105 P53541 Q03674 Q08108	PLB1 PLB2 PLB3 SPO1	Saccharomyces cerevisiae (brewer's yeast)
Hydrolysis of LPC	Lysophospholipase 1 Lysophospholipase 2 Lysophospholipase 3 Putative meiotic phospholipase SPO1 Uncharacterized protein YJR098C	P39105 P47139 P53541 Q03674 Q08108	PLB1 PLB2 PLB3 SPO1 YJR098C	Saccharomyces cerevisiae (brewer's yeast)

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