GlyCosmos Portal

GlyCosmos Pathways

Integrated of pathway data, containing glycoproteins and glycans obtained from Reactome and the Metabolism of carbohydrates in Escherichia coli O-antigens obtained from ECODAB. Search by pathway name, species, and protein name.

Source	Last Updated
Reactome	March 20, 2024
ECODAB	April 1, 2019

Displaying **all 24** entries
Pathway Name	Protein Name	UniProt ID	Gene Symbol	Organism	GlyTouCan ID
Intestinal hexose absorption	Hexose transporter 1 Major facilitator superfamily domain-containing protein, putative	Q7KWJ5 Q8I2V8	HT1 PF3D7_0919500	Plasmodium falciparum (malaria parasite P. falciparum)	G58161NS G93924TT
Neutrophil degranulation	1-cys peroxiredoxin 26S protease regulatory subunit 6A, putative 26S protease regulatory subunit 7, putative 26S proteasome regulatory subunit RPN1, putative 26S proteasome regulatory subunit RPN11, putative 26S proteasome regulatory subunit RPN2, putative 26S proteasome regulatory subunit RPN6 26S proteasome regulatory subunit RPN7, putative 26S proteasome regulatory subunit RPN8, putative 26S proteasome regulatory subunit RPN9, putative 26S proteasome regulatory subunit p55, putative AAA family ATPase, putative AMP deaminase AP-1 complex subunit mu-1 AP-2 complex subunit alpha, putative Actin-like protein, putative Actin-like protein, putative Actin-like protein, putative Actin-like protein, putative Actin-related protein, putative Actin-related protein Arginase Autophagy-related protein 7, putative BEACH domain-containing protein, putative Bax inhibitor 1, putative CCT-beta CCT-theta CSC1-like protein, putative Casein kinase II subunit beta Cdc2-related protein kinase 3 Cell division cycle protein 48 homologue, putative Chitinase Choline transporter-like protein Coatomer subunit beta, putative Cysteine-rich secretory protein, putative Delta-aminolevulinic acid dehydratase Divalent metal transporter, putative Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST3/OST6, putative Dynein heavy chain-like protein 1 Dynein intermediate light chain, putative Dynein light chain, putative Dynein light chain, putative Dynein light chain Dynein light chain Elongation factor 1-alpha Elongation factor 2 Elongation factor Tu, putative Endoplasmin, putative Falcipain-2a Falcipain-2b Falcipain-3 Fructose-bisphosphate aldolase GTPase-activating protein, putative GTPase-activating protein, putative Glucose-6-phosphate isomerase Glutathione S-transferase Guanylate cyclase alpha HECT-type E3 ubiquitin transferase Heat shock 70 kDa protein Heat shock 70 kDa protein Heat shock protein 90, putative Heat shock protein 90 Hexose transporter 1 High mobility group protein B1 Importin subunit beta, putative Inosine-5'-monophosphate dehydrogenase L-dopachrome isomerase LEM3/CDC50 family protein, putative Major facilitator superfamily domain-containing protein, putative Methyltransferase, putative Mitogen-activated protein kinase Nucleoside diphosphate kinase O-acyltransferase P-type ATPase, putative Peptidase, putative Phosphoglucomutase, putative Phosphoglycerate mutase Phospholipid or glycerol acyltransferase, putative Phospholipid-transporting ATPase Phosphotransferase Plasmepsin I Plasmepsin II Plasmepsin III Plasmepsin IV Plasmepsin IX Plasmepsin V Plasmepsin VI Plasmepsin VII Plasmepsin VIII, putative Plasmepsin X Proliferation-associated protein 2g4, putative Proteasome subunit alpha type-2, putative Proteasome subunit alpha type Proteasome subunit beta Protein yippee-like Pyruvate kinase RNA helicase Rab GDP dissociation inhibitor Ras-related protein RAB7 Ras-related protein Rab-18 Ras-related protein Rab-5A Ras-related protein Rab-5C Ras-related protein Rab-6 SNARE protein, putative SSD domain-containing protein Serine repeat antigen 8 Serine/threonine protein phosphatase CPPED1, putative Signal recognition particle 14 kDa protein Sulfhydryl oxidase Trafficking protein particle complex subunit Tubulin beta chain UBX domain-containing protein, putative V-type proton ATPase proteolipid subunit V-type proton ATPase subunit D, putative V-type proton ATPase subunit a, putative Vesicle-associated membrane protein, putative nicotinate phosphoribosyltransferase pyridoxal kinase pyruvate kinase	A0A143ZVI9 A0A143ZVJ8 A0A143ZWJ1 A0A143ZXR3 B9ZSI6 C0H494 C0H4M1 C0H516 C0H568 C0H5C6 C6KST3 C6KT01 C6KT12 C6KT34 C6KT76 C6KTA4 C6KTC6 K7NTP5 O77350 O77368 O96153 O96193 O96220 O97247 O97289 O97295 Q7K6B0 Q7KQK7 Q7KQL5 Q7KQL9 Q7KQM4 Q7KWJ5 Q8I0P6 Q8I0V4 Q8I1T4 Q8I274 Q8I2A2 Q8I2H1 Q8I2K5 Q8I2Q2 Q8I2U5 Q8I2V7 Q8I2V8 Q8I310 Q8I323 Q8I379 Q8I384 Q8I385 Q8I3M7 Q8I3R7 Q8I435 Q8I450 Q8I4R4 Q8I4T2 Q8I4U9 Q8I501 Q8I509 Q8I5C5 Q8I5L4 Q8I5R9 Q8I613 Q8I616 Q8I6T3 Q8I6U4 Q8I6U5 Q8I6V3 Q8I6Z5 Q8IAM2 Q8IAQ8 Q8IAS0 Q8IAU1 Q8IAY9 Q8IB24 Q8IB94 Q8IBG1 Q8IBG2 Q8IBH5 Q8IBI3 Q8IBQ9 Q8IC05 Q8ID28 Q8ID43 Q8IDD2 Q8IDS0 Q8IE53 Q8IEK3 Q8IEK4 Q8IHR8 Q8IHY1 Q8II60 Q8II71 Q8IIA3 Q8IIC2 Q8IIG6 Q8IIL0 Q8IIW5 Q8IIW6 Q8IJ37 Q8IJ71 Q8IJA0 Q8IJM0 Q8IJS0 Q8IKH3 Q8IKI0 Q8IKW5 Q8IL15 Q8IL32 Q8IL68 Q8IL71 Q8ILA4 Q8ILE6 Q8ILG2 Q8ILG6 Q8ILI2 Q8ILQ7 Q8IM15 Q8IM16 Q8IM42 Q8IM55 Q8IM66	ARG CHT1 FBPA FP-2 FP-3 FP2 FP2' FP2A FP2B FP3 GCalpha GST HAP HT1 MAL7P1.162 PF10_0084 PF3D7_0103800 PF3D7_0106800 PF3D7_0107700 PF3D7_0205900 PF3D7_0207300 PF3D7_0211200 PF3D7_0214000 PF3D7_0306800 PF3D7_0311700 PF3D7_0319000 PF3D7_0321500 PF3D7_0322300 PF3D7_0407100 PF3D7_0415300 PF3D7_0505200 PF3D7_0506700 PF3D7_0519200 PF3D7_0523800 PF3D7_0608500 PF3D7_0616000 PF3D7_0617100 PF3D7_0619400 PF3D7_0624000 PF3D7_0626800 PF3D7_0629100 PF3D7_0705800 PF3D7_0707400 PF3D7_0708400 PF3D7_0719300 PF3D7_0719500 PF3D7_0727400 PF3D7_0728200 PF3D7_0729800 PF3D7_0802200 PF3D7_0806800 PF3D7_0807300 PF3D7_0810600 PF3D7_0815200 PF3D7_0818900 PF3D7_0826100 PF3D7_0831700 PF3D7_0903200 PF3D7_0906400 PF3D7_0907200 PF3D7_0912900 PF3D7_0914200 PF3D7_0919500 PF3D7_0919600 PF3D7_0920800 PF3D7_0925600 PF3D7_0927500 PF3D7_0931000 PF3D7_0934700 PF3D7_1012500 PF3D7_1017900 PF3D7_1030500 PF3D7_1033800 PF3D7_1037100 PF3D7_1103600 PF3D7_1103700 PF3D7_1110700 PF3D7_1113900 PF3D7_1120100 PF3D7_1124100 PF3D7_1126100 PF3D7_1129200 PF3D7_1130400 PF3D7_1144900 PF3D7_1202900 PF3D7_1203200 PF3D7_1213600 PF3D7_1219600 PF3D7_1222300 PF3D7_1229400 PF3D7_1242000 PF3D7_1242800 PF3D7_1248500 PF3D7_1250200 PF3D7_1311400 PF3D7_1311500 PF3D7_1320500 PF3D7_1328100 PF3D7_1329400 PF3D7_1341900 PF3D7_1357000 PF3D7_1357300 PF3D7_1366500 PF3D7_1368100 PF3D7_1402300 PF3D7_1403900 PF3D7_1405200 PF3D7_1428300 PF3D7_1429800 PF3D7_1431900 PF3D7_1436000 PF3D7_1439800 PF3D7_1440300 PF3D7_1443900 PF3D7_1445800 PF3D7_1451100 PF3D7_1465700 PF3D7_1466300 PMI PMII PMIII PMIV PMIX PMV PMX	Plasmodium falciparum (malaria parasite P. falciparum)
GP1b-IX-V activation signalling	14-3-3 protein I Inactive protein tyrosine kinase pTKL Tyrosine kinase-like protein, putative Tyrosine kinase-like protein	C0H4V6 C6KT74 Q8IDK6 Q8IIT5	14-3-3I PF3D7_0623800 PF3D7_1349300 pTKL	Plasmodium falciparum (malaria parasite P. falciparum)
Regulation of insulin secretion	Hexose transporter 1 Major facilitator superfamily domain-containing protein, putative	Q7KWJ5 Q8I2V8	HT1 PF3D7_0919500	Plasmodium falciparum (malaria parasite P. falciparum)	G58161NS
Platelet degranulation	Dipeptidyl aminopeptidase 1 Dipeptidyl peptidase 1 Fructose-bisphosphate aldolase Multidrug resistance-associated protein 1 Multidrug resistance-associated protein 2 Obg-like ATPase 1 Protein disulfide-isomerase, putative SNARE protein, putative Saccharopine dehydrogenase, putative Sulfhydryl oxidase Syntaxin-binding protein, putative Tubulin alpha chain Tubulin alpha chain Vacuolar protein sorting-associated protein 33, putative Vesicle transport v-SNARE protein VTI1, putative Vesicle transport v-SNARE protein, putative	A0A143ZX23 C6KSX9 O96268 Q6ZLZ9 Q7KQL9 Q8I0V1 Q8I2G8 Q8I509 Q8I563 Q8I5C7 Q8IBM9 Q8IFP3 Q8II88 Q8IIJ9 Q8IKY7 Q9U0N4	DPAP1 FBPA PF3D7_0112200 PF3D7_0219100 PF3D7_0314100.1 PF3D7_0422300 PF3D7_0613700 PF3D7_0722400 PF3D7_0903700 PF3D7_0935200 PF3D7_1127500 PF3D7_1229100 PF3D7_1236000 PF3D7_1242000 PF3D7_1247800 PF3D7_1448600	Plasmodium falciparum (malaria parasite P. falciparum)
RAF/MAP kinase cascade	Mitogen-activated protein kinase	Q7KQK7	PF3D7_1113900	Plasmodium falciparum (malaria parasite P. falciparum)
MHC class II antigen presentation	Dipeptidyl aminopeptidase 1 Dipeptidyl peptidase 1 Falcipain-2a Falcipain-2b Falcipain-3 Plasmepsin I Plasmepsin II Plasmepsin III Plasmepsin IV Plasmepsin IX Plasmepsin V Plasmepsin VI Plasmepsin VII Plasmepsin VIII, putative Plasmepsin X Serine repeat antigen 8	A0A143ZWJ1 O77350 Q7KQM4 Q8I0V1 Q8I6U4 Q8I6U5 Q8I6V3 Q8I6Z5 Q8IAS0 Q8IIJ9 Q8IIL0 Q8IJ71 Q8IKI0 Q8ILG2 Q8IM15 Q8IM16	DPAP1 FP-2 FP-3 FP2 FP2' FP2A FP2B FP3 HAP PF3D7_0207300 PF3D7_0311700 PF3D7_1033800 PF3D7_1247800 PF3D7_1465700 PMI PMII PMIII PMIV PMIX PMV PMX	Plasmodium falciparum (malaria parasite P. falciparum)
Nitric oxide stimulates guanylate cyclase	NADPH--hemoprotein reductase	C0H553	PF3D7_0923200	Plasmodium falciparum (malaria parasite P. falciparum)
Ub-specific processing proteases	26S protease regulatory subunit 10B, putative 26S protease regulatory subunit 4, putative 26S protease regulatory subunit 6A, putative 26S protease regulatory subunit 6B, putative 26S protease regulatory subunit 7, putative 26S protease regulatory subunit 8, putative 26S proteasome non-ATPase regulatory subunit 9, putative 26S proteasome regulatory subunit RPN1, putative 26S proteasome regulatory subunit RPN10, putative 26S proteasome regulatory subunit RPN11, putative 26S proteasome regulatory subunit RPN12, putative 26S proteasome regulatory subunit RPN13, putative 26S proteasome regulatory subunit RPN2, putative 26S proteasome regulatory subunit RPN6 26S proteasome regulatory subunit RPN7, putative 26S proteasome regulatory subunit RPN8, putative 26S proteasome regulatory subunit RPN9, putative 26S proteasome regulatory subunit p55, putative DEAD/DEAH box helicase, putative Inactive protein tyrosine kinase pTKL PI31 domain-containing protein, putative Polyubiquitin Proteasome activator 28 subunit beta, putative Proteasome activator complex subunit 4, putative Proteasome subunit alpha type-1, putative Proteasome subunit alpha type-2, putative Proteasome subunit alpha type-3, putative Proteasome subunit alpha type-6, putative Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit alpha type Proteasome subunit beta type-6, putative Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Proteasome subunit beta Small ribosomal subunit protein eS1 Tyrosine kinase-like protein, putative Tyrosine kinase-like protein Ubiquitin carboxyl-terminal hydrolase Ubiquitin-60S ribosomal protein L40	C6KST3 C6KT74 O77345 O77379 O77396 O96153 O97313 Q7K6A9 Q7KQK2 Q8I0U7 Q8I1V1 Q8I261 Q8I323 Q8I374 Q8I3J3 Q8I4U5 Q8I6T3 Q8IAR3 Q8IAR6 Q8IAV6 Q8IBI3 Q8ID28 Q8ID50 Q8IDG2 Q8IDG3 Q8IDK6 Q8IEK3 Q8IEQ1 Q8II60 Q8II71 Q8IIT5 Q8IJA0 Q8IJM0 Q8IJT1 Q8IJU4 Q8IJW0 Q8IK90 Q8IKC9 Q8IKH3 Q8IL78 Q8ILV5 Q8IM66	PF3D7_0108000 PF3D7_0205900 PF3D7_0312300 PF3D7_0317000 PF3D7_0317800 PF3D7_0413600 PF3D7_0527200 PF3D7_0608500 PF3D7_0623800 PF3D7_0727400 PF3D7_0803800 PF3D7_0807500 PF3D7_0807800 PF3D7_0812100 PF3D7_0907700 PF3D7_0912900 PF3D7_0931800 PF3D7_1008400 PF3D7_1010100 PF3D7_1011400 PF3D7_1017900 PF3D7_1030500 PF3D7_1129200 PF3D7_1130400 PF3D7_1211800 PF3D7_1248900 PF3D7_1306400 PF3D7_1311500 PF3D7_1328100 PF3D7_1349300 PF3D7_1353800 PF3D7_1353900 PF3D7_1365900 PF3D7_1368100 PF3D7_1402300 PF3D7_1414000 PF3D7_1439100 PF3D7_1466300 PF3D7_1470900 PF3D7_1474800 RPS3A eS1 pTKL	Plasmodium falciparum (malaria parasite P. falciparum)
PDE3B signalling	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase beta Phosphodiesterase cGMP-specific 3',5'-cyclic phosphodiesterase alpha cGMP-specific 3',5'-cyclic phosphodiesterase delta	B3FEM7 Q8I5V4 Q8I6Z7 Q8IKD3	PDE1 PDE2 PDE4 PDEalpha PDEbeta PDEdelta PDEgamma	Plasmodium falciparum (malaria parasite P. falciparum)
Glycolysis	Fructose-bisphosphate aldolase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoglucomutase, putative Phosphoglycerate kinase Phosphoglycerate mutase Phosphotransferase Pyruvate kinase Triosephosphate isomerase pyruvate kinase	C6KT76 C6KTA4 P27362 Q7KQL9 Q7KQM0 Q8IIG6 Q8IJ37 Q8IJS0 Q8IKK7 Q8ILA4	FBPA PF3D7_0624000 PF3D7_0626800 PF3D7_1012500 PF3D7_1037100 PF3D7_1120100 PF3D7_1436000 PF3D7_1462800 PGK TPI	Plasmodium falciparum (malaria parasite P. falciparum)	G58161NS
cGMP effects	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase beta Phosphodiesterase cGMP-specific 3',5'-cyclic phosphodiesterase alpha cGMP-specific 3',5'-cyclic phosphodiesterase delta	B3FEM7 Q8I5V4 Q8I6Z7 Q8IKD3	PDE1 PDE2 PDE4 PDEalpha PDEbeta PDEdelta PDEgamma	Plasmodium falciparum (malaria parasite P. falciparum)
DARPP-32 events	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase beta Phosphodiesterase cGMP-specific 3',5'-cyclic phosphodiesterase alpha cGMP-specific 3',5'-cyclic phosphodiesterase delta	B3FEM7 Q8I5V4 Q8I6Z7 Q8IKD3	PDE1 PDE2 PDE4 PDEalpha PDEbeta PDEdelta PDEgamma	Plasmodium falciparum (malaria parasite P. falciparum)
Ion transport by P-type ATPases	Aminophospholipid transporter, putative Calcium-transporting ATPase Cation transporting ATPase, putative Cation-transporting ATPase Copper-transporting ATPase Guanylate cyclase alpha P-type ATPase, putative P-type sodium-transporting ATPase4 Phospholipid-transporting ATPase, putative Phospholipid-transporting ATPase non-specific serine/threonine protein kinase	A0A143ZZK9 C0H4K5 O77368 Q76NN8 Q8I3A0 Q8I3U7 Q8I5I3 Q8I5L4 Q8IBH9 Q8IHY1 Q8IKF1	ATP4 GCalpha PF3D7_0106300 PF3D7_0319000 PF3D7_0516100 PF3D7_0704500 PF3D7_0727800 PF3D7_0904900 PF3D7_1219600 PF3D7_1223400 PF3D7_1468600	Plasmodium falciparum (malaria parasite P. falciparum)
Gluconeogenesis	Fructose-bisphosphate aldolase Glucose-6-phosphate isomerase Glyceraldehyde-3-phosphate dehydrogenase Phosphoglycerate kinase Phosphoglycerate mutase Triosephosphate isomerase	P27362 Q7KQL9 Q7KQM0 Q8IIG6 Q8IKK7 Q8ILA4	FBPA PF3D7_1120100 PF3D7_1436000 PF3D7_1462800 PGK TPI	Plasmodium falciparum (malaria parasite P. falciparum)
Lactose synthesis	Hexose transporter 1 Major facilitator superfamily domain-containing protein, putative	Q7KWJ5 Q8I2V8	HT1 PF3D7_0919500	Plasmodium falciparum (malaria parasite P. falciparum)	G58161NS
RAF activation	14-3-3 protein I Inactive protein tyrosine kinase pTKL Protein kinase, putative SNF1-related serine/threonine protein kinase KIN Tyrosine kinase-like protein, putative Tyrosine kinase-like protein	C0H4V6 C0H563 C6KT74 Q8IDK6 Q8IIT5 Q8IKT6	14-3-3I PF3D7_0623800 PF3D7_0926300 PF3D7_1349300 PF3D7_1454300 pTKL	Plasmodium falciparum (malaria parasite P. falciparum)
Cam-PDE 1 activation	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase beta Phosphodiesterase cGMP-specific 3',5'-cyclic phosphodiesterase alpha cGMP-specific 3',5'-cyclic phosphodiesterase delta	B3FEM7 Q8I5V4 Q8I6Z7 Q8IKD3	PDE1 PDE2 PDE4 PDEalpha PDEbeta PDEdelta PDEgamma	Plasmodium falciparum (malaria parasite P. falciparum)
G alpha (s) signalling events	Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase beta Phosphodiesterase cGMP-specific 3',5'-cyclic phosphodiesterase alpha cGMP-specific 3',5'-cyclic phosphodiesterase delta	B3FEM7 Q8I5V4 Q8I6Z7 Q8IKD3	PDE1 PDE2 PDE4 PDEalpha PDEbeta PDEdelta PDEgamma	Plasmodium falciparum (malaria parasite P. falciparum)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription	Subtilisin-like protease 1 Subtilisin-like protease 2	Q8I0V0 Q8IHZ5	SUB1 SUB2	Plasmodium falciparum (malaria parasite P. falciparum)
Negative regulation of MAPK pathway	14-3-3 protein I Inactive protein tyrosine kinase pTKL Mitogen-activated protein kinase Protein kinase, putative Protein tyrosine phosphatase, putative Raf kinase inhibitor SNF1-related serine/threonine protein kinase KIN Tyrosine kinase-like protein, putative Tyrosine kinase-like protein Zinc finger protein, putative protein-serine/threonine phosphatase	C0H4V6 C0H563 C6KT74 Q7KQK1 Q7KQK7 Q8I3P9 Q8IDE7 Q8IDK6 Q8IIT5 Q8IKS8 Q8IKT6	14-3-3I PF3D7_0521300 PF3D7_0623800 PF3D7_0926300 PF3D7_1113900 PF3D7_1219700 PF3D7_1349300 PF3D7_1355500 PF3D7_1454300 PF3D7_1455100 pTKL	Plasmodium falciparum (malaria parasite P. falciparum)
Negative feedback regulation of MAPK pathway	Inactive protein tyrosine kinase pTKL Mitogen-activated protein kinase Tyrosine kinase-like protein, putative Tyrosine kinase-like protein	C6KT74 Q7KQK7 Q8IDK6 Q8IIT5	PF3D7_0623800 PF3D7_1113900 PF3D7_1349300 pTKL	Plasmodium falciparum (malaria parasite P. falciparum)
Digestion of dietary carbohydrate	Chitinase	Q8I4R4	CHT1	Plasmodium falciparum (malaria parasite P. falciparum)	G80384UV
Cellular hexose transport	Hexose transporter 1 Major facilitator superfamily domain-containing protein, putative MtN3-like protein	O96245 Q7KWJ5 Q8I2V8	HT1 PF3D7_0216600 PF3D7_0919500	Plasmodium falciparum (malaria parasite P. falciparum)	G58161NS

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