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immunoglobulin light chain amyloidosis

Summary
Synonym
  • AL amyloidosis
  • Amyloidosis primary systemic
  • Light chain amyloidosis
  • Primary AL amyloidosis
  • Primary systemic AL amyloidosis
  • Primary systemic amyloidosis
  • Systemic AL amyloidsis
Definition
An amyloidosis that is characterized by misfolded and aggregated amyloidogenic immunoglobulin light chains produced by marrow clonal plasma cells.
Super Class
amyloidosis heart disease inherited metabolic disorder kidney disease liver disease
External Links
Disease Ontology
DOID:0080933
MeSH
Related Genes
Displaying all 3 entries
Gene ID Gene Symbol Description Source
4312 MMP1 matrix metallopeptidase 1
4313 MMP2 matrix metallopeptidase 2
4314 MMP3 matrix metallopeptidase 3
Displaying all 2 entries
Gene ID Gene Symbol Description Source
17390 Mmp2 matrix metallopeptidase 2
83995 Mmp1a matrix metallopeptidase 1a (interstitial collagenase)
Displaying 1 entry
Gene ID Gene Symbol Description Source
81686 Mmp2 matrix metallopeptidase 2
Displaying all 3 entries
Gene ID Gene Symbol Description Source
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024