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Standards Ontologies Notations
graft-versus-host disease

Summary
Synonym
  • GvHD
  • graft versus host disease
Definition
An immune system disease that is characterized by recognition by mature donor T cells, that contaminate the allogeneic bone marrow, of the recipient's tissue as foreign, causing a severe inflammatory disease characterized by rashes, diarrhea, and liver disease, and that has_material_basis_in an associated with variation in the interleukin-10 gene (IL10) on chromosome 1q32.
Super Class
immune system disease
Disease Ontology
DOID:0081267
Mondo Disease Ontology
MeSH
ORDO
OMIM
Related Genes
Displaying entries 11 - 20 of 33 in total
Gene ID Gene Symbol Description Source
3107 HLA-C major histocompatibility complex, class I, C
3115 HLA-DPB1 major histocompatibility complex, class II, DP beta 1
3133 HLA-E major histocompatibility complex, class I, E
3134 HLA-F major histocompatibility complex, class I, F
3135 HLA-G major histocompatibility complex, class I, G
3303 HSPA1A heat shock protein family A (Hsp70) member 1A
3304 HSPA1B heat shock protein family A (Hsp70) member 1B
3312 HSPA8 heat shock protein family A (Hsp70) member 8
3458 IFNG interferon gamma
3552 IL1A interleukin 1 alpha
Displaying entries 21 - 30 of 30 in total
Gene ID Gene Symbol Description Source
20343 Sell selectin, lymphocyte
20371 Foxp3 forkhead box P3
21788 Tfpi tissue factor pathway inhibitor
22059 Trp53 transformation related protein 53
22339 Vegfa vascular endothelial growth factor A
68395 H2-Q8 histocompatibility 2, Q region locus 8
80908 Abo ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase
110557 H2-Q6 histocompatibility 2, Q region locus 6
193740 Hspa1a heat shock protein 1A
246256 Fcgr4 Fc receptor, IgG, low affinity IV
Displaying entries 1 - 10 of 18 in total
Gene ID Gene Symbol Description Source
24446 Hgf hepatocyte growth factor
24472 Hspa1a heat shock protein family A (Hsp70) member 1A
24493 Il1a interleukin 1 alpha
24628 Pdgfb platelet derived growth factor subunit B
24842 Tp53 tumor protein p53
25325 Il10 interleukin 10
25385 Faslg Fas ligand
25712 Ifng interferon gamma
29259 Sell selectin L
29436 Tfpi tissue factor pathway inhibitor
Displaying 1 entry
Gene ID Gene Symbol Description Source
41840 Hsc70-4 Heat shock protein 70 cognate 4
Displaying all 7 entries
Gene ID Gene Symbol Description Source
30682 vegfaa vascular endothelial growth factor Aa
387303 gbgt1l4 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 4
447881 gbgt1l3 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 3
563897 gbgt1l5 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 5
566487 gbgt1l2 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2
100005565 gbgt1l8 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 8
100005704 gbgt1l9 globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 9
Displaying all 7 entries
Gene ID Gene Symbol Description Source Organism
495825 abo.3.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) L homeolog Xenopus laevis (African clawed frog)
549437 abo.3 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 3 Xenopus tropicalis (tropical clawed frog)
549858 abo.2 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 Xenopus tropicalis (tropical clawed frog)
550054 abo ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 1 Xenopus tropicalis (tropical clawed frog)
100497509 abo.4 ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 Xenopus tropicalis (tropical clawed frog)
108698211 abo.2.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 2 L homeolog Xenopus laevis (African clawed frog)
108698863 abo.4.L ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) gene 4 L homeolog Xenopus laevis (African clawed frog)
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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024