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celiac disease
Summary
- Synonym
-
- celiac sprue
- coeliac disease
- idiopathic steatorrhea
- Definition
- An autoimmune disease of gastrointestinal tract that is caused by a reaction located_in small intestine to gliadin, a prolamin (gluten protein) found in wheat, and similar proteins found in the crops of the tribe Triticeae. The disease is associated with HLA-DQ gene. It has_symptom abdominal pain, has_symptom constipation, has_symptom diarrhea, has_symptom nausea and vomiting, and has_symptom loss of appetite.
- Super Class
- autoimmune disease of gastrointestinal tract
External Links
- Disease Ontology
- DOID:10608
- Mondo Disease Ontology
- MeSH
- UMLS
- NCI Thesaurus
- ORDO
- OMIM
- GARD
Related Genes
| Gene ID | Gene Symbol | Description | Source |
|---|---|---|---|
| 1605 | DAG1 | dystroglycan 1 | |
| 1636 | ACE | angiotensin I converting enzyme | |
| 2524 | FUT2 | fucosyltransferase 2 (H blood group) | |
| 2526 | FUT4 | fucosyltransferase 4 | |
| 2571 | GAD1 | glutamate decarboxylase 1 | |
| 2572 | GAD2 | glutamate decarboxylase 2 | |
| 2720 | GLB1 | galactosidase beta 1 | |
| 3383 | ICAM1 | intercellular adhesion molecule 1 | |
| 3897 | L1CAM | L1 cell adhesion molecule | |
| 3938 | LCT | lactase |
Related Glycoprotein
| UniProt ID | Protein Name | Source |
|---|---|---|
| P09874 | Poly [ADP-ribose] polymerase 1 | |
| P11226 | Mannose-binding protein C | |
| P12821 | Angiotensin-converting enzyme | |
| P13591 | Neural cell adhesion molecule 1 | |
| P14151 | L-selectin | |
| P15813 | Antigen-presenting glycoprotein CD1d | |
| P16070 | CD44 antigen | |
| P16278 | Beta-galactosidase | |
| P16581 | E-selectin | |
| P18827 | Syndecan-1 |
