adult respiratory distress syndrome

Summary
Synonym
  • ARDS
  • Non-cardiogenic pulmonary edema
  • Shock lung
  • acute respiratory distress syndrome
  • adult RDS
Definition
A respiratory failure that results from diffuse injury to the endothelium of the lung (as in sepsis, chest trauma, massive blood transfusion, aspiration of the gastric contents, or pneumonia) and is characterized by pulmonary edema with an abnormally high amount of protein in the edematous fluid and by difficult rapid breathing and hypoxemia.
Super Class
respiratory failure
Disease Ontology
DOID:11394
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
GARD
Related Genes
Displaying entries 1 - 10 of 38 in total
Gene ID Gene Symbol Description Source
12 SERPINA3 serpin family A member 3
177 AGER advanced glycosylation end-product specific receptor
259 AMBP alpha-1-microglobulin/bikunin precursor
718 C3 complement C3
719 C3AR1 complement C3a receptor 1
727 C5 complement C5
728 C5AR1 complement C5a receptor 1
1906 EDN1 endothelin 1
2152 F3 coagulation factor III, tissue factor
3308 HSPA4 heat shock protein family A (Hsp70) member 4
Displaying entries 1 - 10 of 36 in total
Gene ID Gene Symbol Description Source
11596 Ager advanced glycosylation end product-specific receptor
11699 Ambp alpha 1 microglobulin/bikunin precursor
12266 C3 complement component 3
12267 C3ar1 complement component 3a receptor 1
12273 C5ar1 complement component 5a receptor 1
14066 F3 coagulation factor III
14726 Pdpn podoplanin
15139 Hc hemolytic complement
15894 Icam1 intercellular adhesion molecule 1
16153 Il10 interleukin 10
Displaying entries 21 - 24 of 24 in total
Gene ID Gene Symbol Description Source
84007 C3ar1 complement C3a receptor 1
113959 C5ar1 complement C5a receptor 1
156767 Tnfrsf1b TNF receptor superfamily member 1B
192155 Sftpb surfactant protein B
Displaying all 2 entries
Gene ID Gene Symbol Description Source
34091 Spn28Dc Serpin 28Dc
39557 Hsp110 Heat shock protein 110
Displaying all 6 entries
Gene ID Gene Symbol Description Source
178672 srp-3 Serpin domain-containing protein
179125 srp-6 Serpin domain-containing protein
179195 srp-7 Serpin domain-containing protein
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180836 W01C8.5 DM13 domain-containing protein

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Acknowledgements

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Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024