osteoporosis

Summary
Definition
A bone resorption disease characterized by decreased density of normally mineralized bone which results_in the thinning of bone tissue and decreased mechanical strength.
Super Class
bone resorption disease
Disease Ontology
DOID:11476
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 44 in total
Gene ID Gene Symbol Description Source
177 AGER advanced glycosylation end-product specific receptor
367 AR androgen receptor
581 BAX BCL2 associated X, apoptosis regulator
650 BMP2 bone morphogenetic protein 2
796 CALCA calcitonin related polypeptide alpha
799 CALCR calcitonin receptor
1277 COL1A1 collagen type I alpha 1 chain
1278 COL1A2 collagen type I alpha 2 chain
1432 MAPK14 mitogen-activated protein kinase 14
1586 CYP17A1 cytochrome P450 family 17 subfamily A member 1
Displaying entries 11 - 20 of 38 in total
Gene ID Gene Symbol Description Source
13983 Esr2 estrogen receptor 2 (beta)
14600 Ghr growth hormone receptor
14782 Gsr glutathione reductase
15979 Ifngr1 interferon gamma receptor 1
16001 Igf1r insulin-like growth factor I receptor
16002 Igf2 insulin-like growth factor 2
16009 Igfbp3 insulin-like growth factor binding protein 3
16175 Il1a interleukin 1 alpha
16181 Il1rn interleukin 1 receptor antagonist
16367 Irs1 insulin receptor substrate 1
Displaying entries 1 - 10 of 27 in total
Gene ID Gene Symbol Description Source
24241 Calca calcitonin-related polypeptide alpha
24310 Ace angiotensin I converting enzyme
24483 Igf2 insulin-like growth factor 2
24484 Igfbp3 insulin-like growth factor binding protein 3
24493 Il1a interleukin 1 alpha
24536 Lepr leptin receptor
24577 Myc MYC proto-oncogene, bHLH transcription factor
24787 Sod2 superoxide dismutase 2
24890 Esr1 estrogen receptor 1
25149 Esr2 estrogen receptor 2
Displaying all 4 entries
Gene ID Gene Symbol Description Source
33432 dpp decapentaplegic
34189 Acer Angiotensin-converting enzyme-related
34805 Ance Angiotensin converting enzyme
42549 InR Insulin-like receptor
Displaying all 3 entries
Gene ID Gene Symbol Description Source
30686 myca MYC proto-oncogene, bHLH transcription factor a
393141 mycb MYC proto-oncogene, bHLH transcription factor b
565980 ace angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
Displaying all 6 entries
Gene ID Gene Symbol Description Source Organism
380373 cxcr4.S C-X-C motif chemokine receptor 4 S homeolog Xenopus laevis (African clawed frog)
397873 bmp2.L bone morphogenetic protein 2 L homeolog Xenopus laevis (African clawed frog)
398022 igf1r.S insulin like growth factor 1 receptor S homeolog Xenopus laevis (African clawed frog)
100038176 cxcr4 C-X-C motif chemokine receptor 4 Xenopus tropicalis (tropical clawed frog)
100144634 ace angiotensin I converting enzyme Xenopus tropicalis (tropical clawed frog)
100192360 cxcr4.L C-X-C motif chemokine receptor 4 L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
175410 daf-2 Insulin-like receptor subunit beta;Protein kinase domain-containing protein;receptor protein-tyrosine kinase
175942 pdfr-1 Calcitonin receptor-like protein 1
179068 dbl-1 Protein dbl-1
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
180780 acn-1 Inactive angiotensin-converting enzyme-related protein
Displaying 1 entry
Gene ID Gene Symbol Description Source
856014 GLR1 glutathione-disulfide reductase GLR1

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