Sjogren's syndrome

Summary
Synonym
  • Sicca syndrome
  • Sjogren syndrome
  • xerodermosteosis
Definition
An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva.
Super Class
autoimmune disease of exocrine system
Disease Ontology
DOID:12894
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
OMIM
GARD
Related Genes
Displaying entries 11 - 20 of 46 in total
Gene ID Gene Symbol Description Source
1588 CYP19A1 cytochrome P450 family 19 subfamily A member 1
1869 E2F1 E2F transcription factor 1
2668 GDNF glial cell derived neurotrophic factor
3117 HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
3119 HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
3123 HLA-DRB1 major histocompatibility complex, class II, DR beta 1
3187 HNRNPH1 heterogeneous nuclear ribonucleoprotein H1
3383 ICAM1 intercellular adhesion molecule 1
3458 IFNG interferon gamma
3557 IL1RN interleukin 1 receptor antagonist
Displaying entries 11 - 20 of 37 in total
Gene ID Gene Symbol Description Source
14969 H2-Eb1 histocompatibility 2, class II antigen E beta
15894 Icam1 intercellular adhesion molecule 1
15978 Ifng interferon gamma
16153 Il10 interleukin 10
16163 Il13 interleukin 13
16181 Il1rn interleukin 1 receptor antagonist
16183 Il2 interleukin 2
16184 Il2ra interleukin 2 receptor, alpha chain
16189 Il4 interleukin 4
16992 Lta lymphotoxin A
Displaying entries 21 - 25 of 25 in total
Gene ID Gene Symbol Description Source
116562 Il2 interleukin 2
117029 Ccr5 C-C motif chemokine receptor 5
246097 Fas Fas cell surface death receptor
287287 Il4 interleukin 4
378947 Bst2 bone marrow stromal cell antigen 2
Displaying 1 entry
Gene ID Gene Symbol Description Source
447803 pon1 paraoxonase 1
Displaying all 2 entries
Gene ID Gene Symbol Description Source Organism
448598 pon2 paraoxonase 2 Xenopus tropicalis (tropical clawed frog)
779087 gdnf.L glial cell derived neurotrophic factor L homeolog Xenopus laevis (African clawed frog)
Displaying all 6 entries
Gene ID Gene Symbol Description Source
171999 poml-2 Arylesterase
178748 zmp-3 Matrix metalloproteinase-C
179991 zmp-4 Hemopexin;Peptidase metallopeptidase domain-containing protein
180351 W01F3.2 Uncharacterized protein
187297 poml-1 PON (paraoxonase) and MEC-6 Like
188252 lev-9 Protein lev-9

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Last updated: December 9, 2024