low tension glaucoma

Summary
Synonym
  • Normal tension glaucoma
Definition
An open-angle glaucoma characterized by increased intrinsic resistance to aqueous outflow without known secondary causes, an anatomically narrow anterior chamber angle, or elevated intraocular pressure compared to the average population. Normal tension glaucoma has_symptom progressive decreased vision and progressive loss of peripheral vision.
Super Class
open-angle glaucoma
Disease Ontology
DOID:13544
Mondo Disease Ontology
MeSH
UMLS
MGI genotype (from TogoID)
Related Genes
Displaying entries 1 - 10 of 13 in total
Gene ID Gene Symbol Description Source
153 ADRB1 adrenoceptor beta 1
348 APOE apolipoprotein E
627 BDNF brain derived neurotrophic factor
1906 EDN1 endothelin 1
3329 HSPD1 heat shock protein family D (Hsp60) member 1
4653 MYOC myocilin
6505 SLC1A1 solute carrier family 1 member 1
6507 SLC1A3 solute carrier family 1 member 3
6647 SOD1 superoxide dismutase 1
7099 TLR4 toll like receptor 4
Displaying all 10 entries
Gene ID Gene Symbol Description Source
11554 Adrb1 adrenergic receptor, beta 1
12064 Bdnf brain derived neurotrophic factor
15510 Hspd1 heat shock protein 1 (chaperonin)
17926 Myoc myocilin
20510 Slc1a1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
20512 Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
20655 Sod1 superoxide dismutase 1, soluble
21898 Tlr4 toll-like receptor 4
21926 Tnf tumor necrosis factor
22059 Trp53 transformation related protein 53
Displaying all 10 entries
Gene ID Gene Symbol Description Source
24225 Bdnf brain-derived neurotrophic factor
24835 Tnf tumor necrosis factor
24842 Tp53 tumor protein p53
24925 Adrb1 adrenoceptor beta 1
25419 Crp C-reactive protein
25550 Slc1a1 solute carrier family 1 member 1
29260 Tlr4 toll-like receptor 4
29483 Slc1a3 solute carrier family 1 member 3
63868 Hspd1 heat shock protein family D (Hsp60) member 1
81523 Myoc myocilin
Displaying all 3 entries
Gene ID Gene Symbol Description Source
36232 Sod3 Superoxide dismutase 3
41549 Octbeta2R Octopamine beta2 receptor
43222 Tl Toll
Displaying 1 entry
Gene ID Gene Symbol Description Source Organism
108697308 adrb1.L adrenoceptor beta 1 L homeolog Xenopus laevis (African clawed frog)
Displaying 1 entry
Gene ID Gene Symbol Description Source
188744 glt-4 Amino acid transporter;Putative sodium-dependent excitatory amino acid transporter glt-4

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Last updated: December 9, 2024